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MCM Block 2 > Elongation Inhibitors > Flashcards

Elongation Inhibitors Flashcards

1
Q

Puromycin

A

Prokaryotes and Eukaryotes

Causes premature chain termination

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2
Q

Cycloheximide

A

Inhibits eukaryotic peptidyl transferase

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3
Q

Diphtheria Toxin

A

Inactivates eukaryotic eEF2/GTP elongation factor complex

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4
Q

Shiga Toxin and Ricin

A

Blocks eukaryotic 60s large ribosomal subunit tRNA entry

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5
Q

Streptomycin

A

Blocks prokaryotic 30s-50s ribosomal association

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6
Q

Chloramphenicol

A

Inhibits prokaryotic peptidyl transferase

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7
Q

Clindomycin and Erythromycin

A

Binds prokaryotic 50s large subunit and stops translocation

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8
Q

Tetracycline

A

Binds prokaryotic 30s small subunit blocking tRNA

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MCM Block 2 (6 decks)

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