Elongation components Flashcards
1
Q
Helicase
A
Unwinds DNA template at replication fork
2
Q
Primse
A
Synthesizes RNA primer
3
Q
Replication Protein C (RPC)
A
Clamp loader
4
Q
Proliferating cell nuclear antigen (PCNA)
A
Sliding clamp, processivity factor (allows us to keep going especially when making Okazaki fragments
5
Q
Replication protein A (RPA)
A
ssDNA binding protein, holds open replication fork
6
Q
DNA polymerase alpha
A
Adds initial dNTPs onto RNA primer (prepares good “landing space” for pol delta and Epsilon to take over)
7
Q
DNA polymerase delta
A
lagging strand synthesis
8
Q
DNA polymerase Epsilon
A
leading strand synthesis
