Elimination Rxns Flashcards
Which rxn occurs in a single, concerted step: E1 or E2?
E2
what happens in an elimination rxn?
a H gets attacked by a base, and a pi bond is created, resulting in the elimination/kicking off of a leaving group
Does E2 rxn favor strong base or weak base?
strong
Does the SMALL base in E2 rxn favor primary electrophiles or tertiary?
tertiary
Does the LARGE base in E2 rxn favor primary electrophiles or tertiary?
tertiary > secondary > primary
Which elimination rxn makes carbocation intermediates?
E1
Which rxn occurs in a two steps E1 or E2?
E1
Does E1 rxn favor strong base or weak base?
weak
How substituted does E1 like its electrophiles to be?
most substituted
Tertiary > secondary»_space; primary
Which E1 product is favored: cis or trans?
trans
Which elimination rxn requires you to draw/rotate the Newman projection to show that the substrate’s H is 180 degrees from its leaving group?
E2
what kinds of molecules play the role of nucleophiles in elimination rxns? Starts with letter b…
bases
what are 4 of the small, strong bases that can facilitate E2 elimination rxns?
- OH
- OCH3 (aka -OMe)
- OCH2CH3
what are 5 of the LARGE, strong bases that can facilitate elimination rxns?
t-butOK
DMN
DBU
do small, strong bases favor the least substituted opportunity for pi bond, or the most substituted one?
most;
favors the option that creates the most substituted pi bond
