Elements of Pharmacology Flashcards
0
Q
What is Cmax?
A
The peak CONCENTRATION of a drug
1
Q
What is Tmax?
A
The TIME at which a drug’s concentration peaks.
2
Q
What are the qualities of generic drugs?
A
- contain identical active ingredient in identical dose amount.
- demonstrated comparable kinetics in healthy volunteers. (F, AUC, Cmax, Tmax)
- pharmacokinetic equivalence has been demonstrated, not clinical efficacy!
3
Q
what are excipients?
A
glues, dyes, preservatives. these are allowed to vary from the brand-name to the generic form of drug. may cause allergy to one or the other.
4
Q
what is impt about a drug that is adminstered sublingually?
A
will bypass the liver, gets into circulation via the inferior vena cava.
5
Q
what is the definition of pharmacokinetics?
A
what the patient does to the drug. adsorption, distribution, metabolism, excretion.
6
Q
what is the definition of pharmacodynamics?
A
what the drug does to the patient, both intended and unintended.
7
Q
what does F refer to?
A
oral bioavailability. IV = 100%
