Electron Transport Chain Flashcards
Where are the electron transport chains located?
they are embedded in the inner membrane of the mitochondria
Which is more acidic? The cytosol or the mitochondrial matrix?
the cytosol is more acidic. Mitochondrial matrix is more alkaline.
Where does oxidation of NADH take place?
Aerobic oxidation of NADH takes place in the mitochondria
Transportation of NADH and ATP
1) need to get much of the cytosolic NADH into the mitochondria and NAD+ back out
2) Need to get much of the cytosolic ADP and Pi into the mitochondria and the ATP out
How can I make oxa cross the membrane?
Make asp
glu a-KG l\_\_\_\_l oxa -------------> asp
In what organs is the malate-aspartate shuttle dominant?
in the liver, kidney, and heart
Where is the glycerol-3-phosphate shuttle dominant?
in skeletal muscle and brain
Which shuttle allows for cells to get more ATP? glycerol-3-P, or mal-asp shuttle?
mal-asp shuttle = more ATP for cells to use
How are ATP, ADP, and Pi transported across membrane?
mitochondrial electrical gradient used to transport ATP, ADP, and Pi as seem in diagram (draw diagram, ya goof)
Which large complexes are used in e- transport chain?
I, III, and IV (and 2 small electron carriers)
In the mitochondrial electron transport chain electrons are transferred through a series of redox reaction from _________ to _______-
NADH to O2
What is cytochrome C?
- small protein
- diffuses rapidly
- located in the intermembrane space
- carries electrons from Complex III to Complex IV
What is Q in electron transport chain?
- ubiquinone
- small lipid redox partner that moves inside the inner mitochondrial membrane
- small. diffuses rapidly
- between complexes I and III
How many electrons are removed in the conversion of mitochondrial NADH to NAD+? Where do they go?
2 electrons removed.
they are given to Q and then to Complex III
Where do the electrons go from complex III?
to cytochrome C, to complex IV, and then used to reduce O2 to H2O