electron transport Flashcards
The electron transport/oxidative phosphorylation pathway consists of a chain of enzymes and other molecules that results in a high yield
of _______ molecules (metabolic energy)
ATP
In eukaryotic cells, these processes take place in ___________,
as does the TCA cycle
mitochondria
The electron transport/oxidative phosphorylation proteins are
integral membrane proteins of the inner mitochondrial
______________.
membrane
During electron transport, a ________ gradient is established across the
inner mitochondrial membrane.
proton
During ___________, the movement of protons through
the ATP synthase enzyme in the inner mitochondrial membrane
leads to the synthesis of ATP molecules.
oxidative phosphorylation
T or F: The TCA cycle (citric acid cycle) and electron transport/oxidative phosphorylation
pathway are linked by the protons and electrons bound to ATP
FALSE
________is a carrier for protons and electrons in
electron transport:
NADH → NAD+ + H+ + 2e -
NADH
Protons and electrons are both required in the
reaction involving _________:
½ O2 + 2H+ + 2e - → H2 O
oxygen
NAD+ and NADH have central roles in energy generation in the ____________.
mitochondria
T or F: The mitochondria is the size of an E. Coli bacteria
True
the inner membrane of the mitochondria is home to the 4 _____________ __________.
Protein complexes
Human mitochondrial DNA encode 13 proteins, 22 tRNAs and _ rRNAs.
2
In the electron transport chain, electrons and protons are transferred between the protein complexes by
coenzyme Q (UQ) and cytochrome c (cytc). This leads to the transport of protons across the ______
mitochondrial membrane by Complexes I, III, and IV to generate a proton ________ across the membrane.
Inner and gradient
Protons are transported from the mitochondrial
matrix to the intermembrane space by
Complexes ________, _______and ________.
I, III, and IV
The transport of electrons and protons between
the protein complexes is brought about by:
a) Coenzyme Q (CoQ or UQ [ubiquinone])
(b) Cytochrome c (Cytc)
The ETC chain happens between the _________space and the ________ of the mitochondria.
intermembrane and matrix
For example, Complex I has the enzyme name NADH coenzyme Q
reductase, and is also known as _____________ because it contains
the coenzyme flavin mononucleotide (FMN).
flavoprotein 1
As another example, ________ is also known as succinate-
coenzyme Q reductase and as flavoprotein 2, because it binds the
coenzyme flavin adenine dinucleotide (FAD).
Complex II
FMN and FAD are derivatives of _________ (vitamin B2 )
riboflavin
what is the most important protein in the three pathways to making atp?
ATP Synthase
The __ unit catalyzes ATP synthesis.
F1
The F0 unit forms a ____________ pore or channel through which protons move to drive ATP synthesis.
transmembrane
complexes a, b and c are part of which integral membrane protein complex?
F0
The electron transport/oxidative phosphorylation enzymes produce a proton gradient that
results in ____________ _________ in ATP synthase and leads to ATP synthesis.
conformational changes
