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2.a. Biochemistry > Electron Transport > Flashcards

Electron Transport Flashcards

0
Q

Piericidin A

A

NADH dehydrogenase inhibitor in complex 1

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1
Q

Rotenone

A

Inhibits NADH dehydrogenase in complex 1

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2
Q

Amytal

A

Barbiturate

Inhibits NADH dehydrogenase in complex 1

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3
Q

Oligomycin

A

ATP synthase inhibitor, complex 5

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4
Q

Atractyloside

A

Blocks outward facing portion of the adenine nucleotide transporter

Inhibits ATP/ADP transport

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5
Q

Thermogenin

A

Dissipates H+ gradient in ETC. Generates heat.

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6
Q

Bongkrekic acid

A

Binds inward facing portion of adenine nucleotide transporter.

Inhibits ATP/ADP transport

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7
Q

Ionophores

A

Makes inner membrane permeable to compounds that usually cannot cross.

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8
Q

Gramicidin

A

Channel forming ionophore

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9
Q

Valinomycin

A

Mobile carrier ionophore typically carries K+

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10
Q

NADH dehydrogenase

A

Complex 1

NADH + FMN to NAD+ and FMNH2

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11
Q

Succinate dehydrogenase

A

Complex 2

Succinate and FAD to Fumarate and FADH2

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12
Q

Cytochrome reductase

A

e- passed between Fe molecules in complex III

Delivered to complex III by CoQ and removed (reduced) by Cytochrome C

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14
Q

Cytochrome Oxidase

A

Oxidation of cytochrome C and reduction of O2 in complex IV

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15
Q

Glycerol phosphate shuttle

A

NADH into mitochondria

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16
Q

Malate-aspartate shuttle

A

NADH into mitochondria

2.a. Biochemistry (14 decks)

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