Electrocardiographic Waveform Acute Ischemia and Infarction Flashcards
What is Acute myocardial ischemia and infarction?
Series of metabolic, ionic, and pathological changes in the region supplied by the occluded coronary artery that cause characteristic changes in the ST segment QRS complex and T wave
What is the sequence of ECG changes associated with acute ischemia and infarction?
1: Peaking of T wave
2: ST segment elevation or depression
3: development of abnormal Q waves
4: T wave inversion
What is the earliest ECG manifestation of acute transmural ischemia?
Peaking of the T wave
What is the most frequently observed early ECG in the hospital
ST elevation and depression
What causes the ST changes?
Voltage gradients across the border between the ischemic and non ischemic regions that result in a electrical current flowing across the ischemic border.
What are the factors that cause ST Elevation or Depression
Extent
Location of the Ischemic Zone
Relationship of the ECG electrodes to the ischemic zone
Electrodes that directly overlie the region of ischemia will record what and the other electrodes will record what?
-ST elevation
ST depression or no change
What is Subendocardial Ischemia?
Damage to the subendocardial layer of the left ventricle
What causes subendocardial ischemia?
Often brought on by exercise in patients with flow limiting coronary artery obstruction.
What will show in all leads during a sub endocardial ischemia?
ST depression
What does development of Q waves indicate?
Absent conduction through the infarcted region and may last indefinently
What mimic abnormal Q waves that is associated with infarction?
Hypertrophy of the interventricular septum and interventricular conduction disturbances. Such as ventricular preexcitation.
Various ECG changes in an acute transmural ischemic event help with what?
Localization
Estimation of the extent of the ischemic or infarcted region
Identification of the occluded vessel
What does the ECG waveform consist of?
P wave
PR interval
QRS complex
ST segment
T wave
U wave
What does the P wave reflect?
Depolarization of the Atria
QRS reflects?
Depolarization of the Ventricles
What does the ST segment and T wave reflect?
Repolarization of the ventricles
What does the U wave reflect?
After the T wave and is believed to be a electromechanical event coupled to ventricular relaxation
When does the depolarization of the sinus node occur?
Before the P wave, but it is too small to be recorded on the ECG machine
When does the electrical activity of the AV node and His-Purkinje system occur?
During PR interval, electrically silent