Aortic Valve Disease Flashcards

1
Q

What does aortic stenosis impair?

A

Left ventricular outflow

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2
Q

Aortic stenosis symptoms include? (3)

A

Angina
Syncope
Dyspnea

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3
Q

When does systolic murmur peak for aortic stenosis?

A

Mid to late systole

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4
Q

What diagnostic testing is the most useful that confirms and quantifies the severity of stenosis?

A

Echocardiography

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5
Q

Aortic regurgitation may present acutely in the setting of?

A

Endocarditis

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6
Q

How many pocket like cusps are on the aortic valve?

A

Semilunar valve that includes 3 pocket like cusps of normal equal size

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7
Q

When does the normal aortic valve open?

A

Completely during systole.

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8
Q

What is the most common cause of LV outflow obstruction?

A

Valvular aortic stenosis (AS)

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9
Q

What accounts for two thirds of aortic valve replacements for AS in patients younger than 70?

A

Bicuspid valve in the Aortic valve

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10
Q

What is the main diagnosis of patients with AS after age 70?

A

Calcific degeneration

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11
Q

When does rheumatic AS present between for age?

A

30 and 50 years old

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12
Q

Imaging in a aortic dilation case with patients with a bicuspid aortic valve, what is the measurement recommended for a surgical center?

A

> 4.5 cm

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13
Q

Approximately how many people who have angina with severe AS also have significant coronary artery disease?

A

one half

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14
Q

What are other clinical manifestations of AS? (3)

A

GI bleeding
Embolic events (stroke)
Infective endocarditis

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15
Q

What are the 3 key focus areas in a physical examination for AS?

A

Evaluation of the carotid artery
Auscultation of the murmur
Second heart sound

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16
Q

What can identify the location of the aortic outflow obstruction, estimate the severity of valvular obstruction and provide information about LV function?

A

Transthoracic echocardiogram

17
Q

Most common ECG findings in late stage AS? (2)

A

LVH >80% and LA hypertrophy

18
Q

Coronary angiography is necessary to identify what in all patients older than what that require AVR?

A

CAD
older than 35

19
Q

when there is inconclusive information for AS, what is used to discover hemodynamic measurements?

A

Left and right heart cath to obtain pressure gradients and measure cardiac output

20
Q

Aortic root replacement is considered when the diameter is?

A

> 5.1 to 5.5 cm or over 4.5 if AVR is indicated

21
Q

When can AVR be delayed until?

A

Symptoms develop

22
Q

When can TAVR be used to replace AVR (3)

A

For inoperable
high risk
intermediate surgical risk patients

23
Q

What does Aortic valve regurgitation (AR) result in? (2)

A

Impaired cardiac output
Volume overload of the LV

24
Q

What needs to be distinct of AR because it informs etiologies, associated diseases, prognosis, and treatment?

A

Acute or chronic forms of AR

25
Q

What is responsible for approximately 50% of cases of AR?

A

Aortic root disease

26
Q

What is the mortality rates of people with AR with symptoms?

A

10-20%

27
Q

What is the percentage of patients who died or progressed to LV dysfunction without symptoms?

A

25%

28
Q

Patients with acute AR usually appear? (5)

A

Severely ill
Tachycardia
Hypotension
Vasoconstriction
Pulmonary Edema

29
Q

When acute volume overload is poorly tolerated in the LV, it results in? (5)

A

Increased LA pressure
Pulmonary capillary wedge pressures,
pulmonary edema
Forward cardiac output reduction
Sinus Tachycardia

30
Q

Aortic root disease causes the murmur to be louder to what location?

A

Right of the sternum

31
Q

Hemodynamic tracings in severe AR show? (2)

A

A wide pulse pressure and elevated LV end-diastolic pressure.

32
Q

What does aortic root angiography provide? (2)

A

Assessment of severity
Qantitative calculations

33
Q

Surgery is strongly recommended in asymptomatic patients with AR who have a depressed LV EF of?

A

<50%