Elderly Care Flashcards

1
Q

Define frailty

A

A group of older people who are at highest risk of adverse outcomes such as falls, disability, admission to hospital, or the need for long term care

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2
Q

Why should we focus on frailty

A

A gradual multi system loss of physiological reserves and of homeostatic robustness- resulting in lower resilience and increased vulnerability

Often present to health services after a minor change, but with serious (often non specific) symptoms, such as falls, inability to mobilise to provide self care and/or confusion

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3
Q

What are the formal frailty assessments

A

British Geriatric society recommends:

  1. GAIT speed- taking more than 5 seconds to cover 4m
  2. Timed up and go test- taking more than 10 seconds to get up a chair, walk 3m, turn and sit back down
  3. PRISMA 7 Questionnaire- prompts further assessment
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4
Q

If someone is suggested to have frailty due to assessment by geriatrician, what should be done

A

A Comprehensive Geriatric Assessment (CGA)

  • Holistic interdisciplinary assessment of a patient with comprehensive care and support plan (CSP)
  • Time consuming (>1hr) and requires full multi-disciplinary team
  • Not done in acute setting

In patient assessment
- Clinical frailty scale or frail assessment

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5
Q

Describe the STOPP/START Tool v2 and what it is validated to do?

A

Screening Tool of Older Persons’ potentially inappropriate prescriptions (STOP)

Screening Tool to Alert doctors to Right (indicated) Treatment (START)

Validated to:
Significantly reduce adverse drug reactions

Improve medication appropriateness

Reduce length of hospital stay in those hospitalised with acute illness

Integrated into some Trust formularies and CCG’s

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6
Q

Describe what the PINCER intervention is

A

A pharmacist led IT intervention to reduce prescribing errors in primary care

System to identify patents at risk from common and important prescribing errors (some which may be elderly)
- Patients who have a diagnosis of heart failure who are prescribed an NSAID (contraindicated)

Pharmacy technicians support this as it is IT databased focused

Identifies at risk patients for medication reviews

NICE supported

COST EFFECTIVE

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7
Q

What is medication/polypharmacy review

A

STOPP/START toolkit as a start

PINCER intervention in primary care

Anticholinergic burden

Consider national and regional guidance

Optimise pain relief- considered in stop and start, but often mismanaged
- Paracetamol regularly may help, buprenorphine patch if compliance is an issue

Holistic approach

Involve carers and family

Consider degree of frailty when making recommendations- frailty score
- wouldn’t want to give someone all these drugs that give her more side effects

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8
Q

What are the reasons for falls from medicines

A
Sedation
Impaired postural stability (balance) 
Hypotension- low BP
Drug induced parkinsonism (parkinson like symptoms)
Visual impairment
Hypoglycaemia
Vestibular damage (tinnitus, deafness)
Hypothermia (low body temp)
Confusion
Dehydration
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9
Q

What are the conditions and drugs that cause sedation

A
Conditions: 
Depression
Sleep apnoea 
Electrolyte imbalance
Hypothyroidism
Chronic pain
Vitamin and mineral deficiency 
Benzodiazepines
Antipsychotics
Dopamine agonists
Phenobarbital
Anti-cholinergic's
Muscle relaxants
Opiate analgesics
Z-drugs: zopiclone etc
Carbamazepine
Sedating anti-histamine
Sedating anti-depressants
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10
Q

What are the conditions and drugs that cause impaired postural stability

A
Conditions
Labyrinthitis
parkinsons disease
Meziere's 
Multiple Sclerosis
Diabetes 
Stroke
Drugs
Benzodiazepines
Anti-psychotics
Z-drugs
Opiate analgesics
Muscle relaxants
Sedating anti-depressants
Phenytoin
Sedating anti-histamines
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11
Q

What are the conditions and drugs that cause hypotension

A
Infection
Parkinson's disease
Dehydration
Heart failure
Hypothyroidism
Valvular disease
Alpha blockers
Diuretics
Beta blockers
Anti-hypertensives
MAOIs
SNRIs
Anti-psychotics
Anti-anginas
Sedating anti-depressants
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12
Q

What are the conditions and drugs that cause parkinsonism

A
Brain injury
Lewy body disease
Encephalitis/meningitis
Stroke
Brain tumour
Liver disease
Atypical antipsychotics- at high doses
Metoclopramide
Methyldopa
Cinnarizine 
Typical 1st generation anti-psychotics
Tetrabenzine
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13
Q

What are the conditions and drugs that cause visual impairment

A
Diabetes
Glaucoma
Brain injury
Cataracts
Stroke 
Parkinson's disease
Benzodiazepines
Amiodarone
Ethambutol 
Sedating anti-histamines
Anti-psychotics
Topiamate
Sedating anti-depressants 
Alpha blockers
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14
Q

What are the conditions and drugs that cause hypoglycaemia

A
Diabetes
Malnutrition
Alcohol 
Renal failure
Exercise
Hormone deficiencies 
Insulin
Quinine
Sulphonylureas
Metaglinides
ACE inhibitors
Beta blockers
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15
Q

What are the conditions and drugs that cause vestibular damage

A
Infection
Ear blockage
Stroke
Multiple sclerosis
Noise induced hearing loss
Paget's disease
Loop diuretics
Salicylates
Quinine
VINCA ALALOIDS (CHEMO)
Platinum based chemo 
Amino glycoside antibiotics
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16
Q

What are the conditions and drugs that cause hypothermia

A
Hypothyroidism
Alcohol 
Addison's disease
Metabolic disorders
Heart failure
Malnutrition
Beta blockers 
Benzodiazepines
Anti-psychotics
Sedating anti-histamines
Z-drugs
Sedative anti-depressants
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17
Q

What are the conditions and drugs that cause confusion

A
Hypothyroidism
Delirium
Infection
Dementia 
Heart failure
Electrolyte disturbance
Dopamine agonists
Benzodiazepines
Z-drugs
Sedative anti-histamines
Anti-psychotics
Anti-cholinergic's
MAOIs
Opiate analgesics
Sedative anti-depressants
18
Q

What are the conditions and drugs that cause dehydration

A
D+V
Fever
Alcohol 
Diabetes 
Dementai 
Delirium
Diuretics
ACE inhibitors
ARBs
Colchicine 
Laxatives
19
Q

What are the risks from elderly falls and why do they occur

A

Mortality

Immobility and inactivity

Prolonged hospital admission

Loss of independence

Osteoporotic fracture- inactivity, decline in oestrogen or testosertone, higher levels of PTH, low levels of vitamin , calcium, smoking, medication, alcohol

Cerebral haemorrhage- slower reflexes, vascular fragility, higher rates of hypertension, use of anti-platelets and anti-coagulants

Limitation of further activity- self imposed due to perceived risk of future falls

20
Q

How do you prevent falls

A

Identification of falls history

Assessment of gait, balance, mobility and muscle weakness

Assessment of osteoporosis risk

Assessment of perceived functional ability and fear relating to falling

Assessment of visual and hearing impairment and use of appropriate aids

Assessment of cognitive impairment and neurological examination

Assessment of home hazards

Cardiovascular examination

Sturdy footwear

Medication review

Continence support

Regular diabetes foot checks

Social care support for daily living tasks if necessary

Avoid and reduce alcohol intake

21
Q

Define Delirium

A

Acute cognitive impairment syndrome

Characterised by impairment of consciousness and cognition that normally develops over hours to days (short time period)

Usual presentation

  • Disturbed sleep
  • Restless and hyperactive or sluggish and lethargic
  • Emotional disturbances- mood changes, disorientated time and place
  • Reduced awareness of environment- more impairment in evening or night
22
Q

What is the mnemonic for delirium

A

D- disorientated with respect to place, time and person

E- emotionally labile

L- level of consciousness is impaired and subject to fluctuations

I- Integration- perceptions are impaired

R- Rapid onset- hours to days

I- Irrelevant stimuli distract patients easily

U- Utterances- incoherent speech

M- Memory impairment- short term memory especially

23
Q

What is Delirium usually due to and the precipitating causes

A

Due to at least one of:
Acute medical condition
Drug induced
Withdrawal of drug

Precipitating causes:
Advanced age
Pre-existing cognitive impairment- dementia 
Nutritional deficiency- thiamine
Sensory deprivation 
Post surgery
24
Q

Describe what causes acute medical conditions in Delirium

A

Infection- urinary tract infection and respiratory

Hypoxia- heart failure, severe anaemia and COPD

Metabolic- dehydration, electrolyte disturbances, liver failure, hypoglycaemia and thyrotoxicosis

CNS- brain trauma, ischaemia, neurodegeneration, epilepsy

Hypothermia

Multiple organ failure

Pain

Urinary retention

25
Describe what causes drug induced Delirium
Anti-parkinsonian drugs- anti-cholinergic or dopaminergic effects Analgesia- except paracetamol Anti-Psychotics- sedating ones- chlorpromazine Benzodiazepines- more common on initial treatment Diuretics- due to electrolyte balance Long acting oral hypoglycaemics- glibenclamide can cause hypoglycaemia and hyponatraemia Aminophylline and digoxin- NTI- check levels Tricyclic anti-depressants - anti-cholinergic and sedative effects Steroids- dose related risks- hallucinations common
26
What drugs should be withdrawn in Delirium patients
Alcohol (common) Benzodiazepines Opioids Drugs of abuse (cocaine, amphetamines)
27
How do you assess delirium
Confusion assessment method It is delirium based on: Acute onset and fluctuating course Inattention Disorganised thinking Altered level of consciousness
28
How do you manage delirium
Treat underlying medical cause Review medications Adapt environment if necessary Ensure regular personal orientation- clocks, calendar, window Use all aids- glasses and hearing aids Continuity of care Encouragement of mobility Maintaining good fluid intake Reviewing old age psychiatry services Last choice- sedative use to control behaviour
29
How do you use sedatives in delirium and why do we need to use them
Last resort, short term (1 week or less): - Haloperiodol 0.5mg to 1mg up to 2 hourly PRN (off license) - Olanzapine 2.5mg to 5mg up to TDS PRN (off license) - Can be given IM or PO, more potent when given parenterally - Lorazepam 0.5mg to 1mg up to BD PRN (off license) - If haloperidol or olanzapine contraindicated due to parkinsons disease or lewy body dementia Reason to use: Aim to calm the patient not sedate them Risks vs benefits need to be considered Associated with unrelieved pain, treat any reversible causes, trial of haloperiold or leveomepromazine
30
Describe main changes elderly patients ageing eye and what it can lead to
``` Main changes: Cataract Macular degeneration Glaucoma Retinal disease Dry eyes ``` ``` Leads to: Decline in visual activity Difficulty seeing in glare Difficulty in dark adaptation Narrowing of visual field ```
31
What causes cataracts in elderly patients and the risk factors
Develop due to oxidative damage to lens Impaired transmission of light to retina Risk factors: - Diabetes - Smoking - UV light exposure - Use of corticosteroids Resolved surgically with artificial lens
32
What causes macular degeneration in elderly patients (risk factors) and the two forms
Leading cause of blindness Two forms: Progressive dry form- small granular deposits in retina Aggressive wet form- new weakly blood vessels form in macula which lead to distorted vision- treatment with anti-VGEF drugs injected into virtual cavity- Ranibizumab Risk factors: Smoking Female gender
33
What causes Glaucoma in elderly patients, including risk factors and the two forms
Optic neuropathy due to raised intra-ocular pressure Leads to loss of visual field Symptoms arise when irreversible damage has occurred ``` Risk factors: Increasing age Afro-carribean ethnicity Family history Myopia- short sighted Diabetes Use of long term corticosteroids ```
34
What are the two main types of glaucoma and what are the treatment aims
Open angle: Drainage angle for aqueous fluid is open but fluid drains too slowly through the meshwork meaning intraocular pressure rises Narrow and closed angle: Drainage angle for aqueous fluid is narrow or closed completely by part of the iris Patients are at risk of sudden spikes in intra-ocular pressure that require emergency treatment- spikes associated with sudden onset of pain, nausea and blurred vision Aims: Reduce rate of aqueous humour production Increase rate of outflow
35
What are the Glaucoma treatment options
Prostaglandin analogues- increased outflow on aqueous fluid- OD- Latanoprost, Travoprost, Bimatoprost Side effects: Local increased eyelash growth and iris pigmentation Beta blockers- reduced production on aqueous fluid- OD to BD- Timolol, Carteolol Side effects: local irritation, systemic bradycardia and bronchoconstriction Alpha-agnost- increased outflow and reduced production of aqueous fluid- BD to TDS- Brimonidine, Dorzolamide Side effects: local irritation, redness, systemic fatigue, dizziness and dry mouth Miotics- increase outflow- BD to TDS- Pilocarpine- Local headache and poor vision, twitching eye, lacrimation Osmotic diuretics- increase outflow by osmotic diuresis- IV- mannitol, glycerol- hypotension
36
What is Diabetic retinopathy in elderly patients, including risk factors and treatment options
Inadequate perfusion of the eye leading to new vessel formation and oedema leading to retinal damage Decreased corneal sensation, leads to dry eyes and corneal ulcers Increased risk of cataracts and glaucoma at younger age Treatment None other than try and preserve function with good glycemic control Risk factors: Poor glycemic control Long standing diabetes Co-morbidies (hypertension)
37
What is dry eyes in elderly patients, including causes and treatment
Very common Results in irritation which paradoxically causes watering Symptoms= burning sensation or sensation of foreign body Causes: drugs like anticholinergics, irritant eye drops, parkinson's disease (reduced blinking), rheumatological conditions, Sjorgen's syndrome (immune system attacks salivary glands and tear glands- treat with pilocarpine) Treatment: Use preservative free eye drops Avoid anticholinergics where possible Use topical lubricant eye drops- hypromellose, carbomer
38
What is urinary incontinence (stress and urge) and retention (chronic and acute) in elderly men
- Incontinence= unintentional passing of urine - More common in women Stress incontinence: spontaneous loss of urine not associated with urge to urinate- when coughing or laughing Urge incontinence: spontaneous loss of urine with an intense urge to urinate Chronic retention: inability to pass full bladder of urine Acute retention: abrupt inability to pass any urine (emergency) More common in men Happens due to: urethral blockage, drugs (anticholinergics), BPH (most common)
39
How do you treat incontinence
Life style changes Pelvic floor exercises Bladder training Incontinence products: Overactive bladder: - Oxybutynin, tolterodine or darifenacin are first line - Mirabegron (Beta 3 adrenoceptor agonist) is used when unable to take antimuscarinic drug) - Botox injection into bladder wall is option if oral option doesn't work - Various surgical techniques- last line
40
Who do you treat retention
Licensed alpha blocker like tamsulosin High risk BPH patients, consider 5-alpha reductase inhibitor like finasteride to reduce risk of progression to cancer Catheterisation if necessary- temporary or permanent
41
What are the medication challenges an elderly patient may face
Dysphagia secondary to stroke- Nasogastric or PEG tube Drug- feed interactions like phenytoin Tablet/capsule: liquid conversions Dexterity-can they open a click bottle, pick up very small tablets or read label Compliance aids- dosette box, alarmed box, PD medication alarm Rationalised medications Safe use of warfarin and NOACs Use of patient decision aids in making evidence based choices