Eivind Almaas - Systems Biology Flashcards
1
Q
Describe the three primary fundamental concepts in constraint-based reconstruction and analysis methods
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2
Q
Reason why optimization of biomass production is a reasonable objective when modeling microbes
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3
Q
Briefly discuss reasons for why the “simplistic” FBA method works so well in predicting cellular phenotypes
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4
Q
Is it possible to model genetic perturbations using COBRA methods? If yes, briefly explain how.
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5
Q
Briefly describe three limitations for current implementations of constraint-based modeling
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