Egleton Flashcards
Side effects of lithium
polyuria/ polydipsia
What is phenelzine
irreversible inhibitor
What is sertralines MOA
inhibit serotonin reuptake
What do you treat jitters with when someone has started an SSRI
a benzodiazapine (midazolam, diazepam, and lorazepam)
What is venlafaxines MOA
inhibit Norepinephrine and serotonin reuptake
What do secondary TCAs block? What are they
Norepinephrine
Desipramine
Nortryptiline
What do tertiary amines block?
Serotonin
What can you give to a elderly person with hepatic failure
orazepram
oxazepam
What are benzos MOA
bind GABA-A and cause increased Cl- channel opening
What can lamotragine cause
Steven Johnson Syndrome
What is the antidote for benzodiazapines
Flumazenil
What does busprione do
agonist at 5-HTIA
used for GAD
What does propanolol do
decrease somatics
used for short term test anxiety
What do you use in opioid overdose
naloxone
What receptor do opioids bind
mu receptor for pain
What is given as a chronic treatment for drug addiction
naltrexone
What is morphines MOA
mu receptor agonist
what does morphine cause
constipation
What is codeine metabolized to and by what
morphine by CYP2D6
What treats trigeminal neuralgia
carbamazapine
What does clonidine do
alpha 2 adrenergicagonist
What treats diabetic neuropathy best
gabapentin
What does Baclofen act on
GABA-B receptor agonist
What does loperamide act on
mu
Which are antidiharreal with no CNS avtivity
loperamide
diphenoxylate
What causes a rebound effect and difficulty going to sleep if you forget to take your pills
triazolam
What would you give to someone to make them sleep on a long car ride
Diphenhydramine, and H1 antagonist
What does disulfiram do
causes a buildup of acetaldehyde
What does modafinil help treat
narcolepsy
What does buprenorphine act on
u agonist
k antagonist
What deals with hyperactive, positive symptoms in schizophrenia
mesolimbic pathway
What do typical antipsychotics block
D2
What do atypical antipsychotics block
5-HT2
Rank weight gain for antipsychs
Clozapine > Risperidone > Haloperidol
What pathway deals with negative symptoms in schizophrenia
mesocortical
What causes inc serum prolactin and blurred vision
Chlorpromazine (Phenothiazines)
What potentiates cocaine
alcohol due to formation of cocaethylene
???What is the withdrawal symptom for nicotine???
anxiety
???What is the withdrawal symptom for caffeine???
irritability
What does ketamine do
antagonize glutamate action by blocking NMDA
What do native americans use at ceremonies
peyote
What is most likely to cause extrapyramidal symptoms
typical antipsychotics
Zines and haloperidol
What is found in urine of those who use heroin
6-monoacetylmorphine
What do you see in opioid withdrawal
dilated pupils
inc bowel sounds
hypotension
What potentiates opioids
gabapentin
What do you see in opioid overdose
constricted pupils
dec bowel sounds