Effects of Increased & Decreased Loads on CT

Question 1

Tendon & Ligament Decreased Load

Answer 1

Decreased collagen concentration, cross-linking, tensile strength

Question 2

Tendon & Ligament Increased Load

Answer 2

Increased cross-sectional area, collagen concentration, cross-linking, tensile strength, stiffness

Question 3

Menisci Decreased Load

Answer 3

Decrease PGs

Question 4

Menisci Increased Load

Answer 4

Increase PGs

Question 5

Bone Decreased Load

Answer 5

Decreased collagen synthesis & bone formation

Increased bone resorption

Question 6

Bone Increased Load

Answer 6

Denser bone

Increased synthesis of collagen & bone

Question 7

Cartilage Decreased Load

Answer 7

Thinning of cartilage
Advancing of subchondral bone
Decreased PG synthesis
Fewer PG aggregates

Question 8

Cartilage Increased Load

Answer 8

Increased PG synthesis

Question 9

Joint Capsule Decreased Load

Answer 9

Disordered collagen fibrils

Abnormal cross-linking

Question 10

Synovium Decreased Load

Answer 10

Adhesion formation

Fibrofatty tissue proliferation into joint space

Question 11

CT w/ Compression

Answer 11

Cartilage & bone

Question 12

CT w/ Tension

Answer 12

Ligament & tendon