Edema Flashcards
T/F: Edema = clinically apparent soft tissue swelling due to expansion of the intracellular interstitial volume with no alteration in Starlings forces
False. Expansion of the EXTRAcellular interstitial volume WITH alteration in Starlings forces
Total Body Water= ___ ICF + ___ ECF
2/3 ICF
1/3 ECF
ECF= ___ Interstitial Fluid + ___ Plasma
3/4 interstitial fluid
1/4 plasma
Hydrostatic pressure = the forces driving fluid movement (into/out of) the capillary
out of
Oncotic Pressure = the forces driving fluid movement (into/out of) the capillary, due mostly to ____
into
plasma proteins
Extracellular fluid moves between interior of vasculature and interstitial space dependent based on all of these changes EXCEPT:
A. hydrostatic and oncotic pressure gradients
B. Permeability of capillary membrane
C. Integrity of lymphatic system
D. Viscosity of the blood
D
Define the variables:
Edema= Kf[(Pin – Pout) - σ(πin – πout)]
Kf = filtration coefficient σ = reflection coefficient Pin = hydrostatic pressure of the capillary Pout = hydrostatic pressure of the interstitial fluid πin = oncotic pressure of the capillary πout = oncotic pressure of the interstitial fluid
All of the following are causes edema due to (decreased/increased) Hydrostatic pressure (Pin) EXCEPT:
A. CHF
B. Nephrotic syndrome
C. Cirrhosis
increased
B. Nephrotic syndrome is due to decreased oncotic pressure
All of the following are causes edema due to (decreased/increased) Oncotic pressure (πin ) EXCEPT: A. Cirrhosis B. Nephrotic syndrome C. Angioneurotic edema D. Malnutrition E. Pregnancy
decreased
C. Angioneurotic edema is due to increased vascular permeability
All of the following are causes edema due to increased vascular permeability EXCEPT:
A. Burns
B. Angioneurotic edema
C. Systemic Inflammatory Response Syndrome
D. Malignancy
E. IL-2 therapy
D. Malignancy is due to obstruction of lymphatic flow
Malignancy and CHF cause edema due to ____
obstruction of lymphatic flow
CHF causes edema due to all of the following EXCEPT:
A. Increased hydrostatic pressure
B. Increased vascular permeability
C. Obstruction of lymphatic flow
B
Cirrhosis causes edema due to all of the following EXCEPT:
A. Increased hydrostatic pressure
B. Decreased oncotic pressure
C. Obstruction of lymphatic flow
C
T/F: Exudate is caused by alteration of Starling Forces
False. Transudate
Exudate = increased capillary and vascular permeability, inflammatory
Transudate has extravascular fluid with (low/high) protein content; (low/high) cellularity
Low
Low
