Ectoparasiticides Flashcards

1
Q

Who controls all insecticides and pest control products that have not undergone FDA testing?

A

EPA

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2
Q

True or False: you are only allowed to legally use a product as directed by manufacturer and evaluated by the EPA (as labeled)

A

True

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3
Q

Which agency has higher jurisdiction, EPA or FDA?

A

FDA

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4
Q

Off label drug use is permitted if deemed necessary by which agency?

A

FDA

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5
Q

Which FDA-approved drug can you not break the package and give as a single dose?

A

Advantage multi

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6
Q

What are your oral miticidal treatment options for Demodex?

A
  • Milbemycin (daily)
  • Ivermectin (daily)
  • Sarolaner (all -laners are monthly)
  • Fluralaner (can be used as topical for cats - Bravecto)
  • Afoxolaner
  • Lotilaner
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7
Q

What drugs should you always avoid with demodex?

A

steroids - can make infection worse

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8
Q

What are your topical miticidal treatment options for Demodex?

A
  • Amitraz (weekly dip)
  • Moxidectin/imidacloprid (q1-4 wk application)
  • Rotenone (Goodwinol) - daily
  • Lime sulfur’s (CATS - WEEKLY)
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9
Q

What should some of your concerns for demodex treatment be?

A
  • NO STEROIDS
  • Heartworm status - macrocyclic lactones
  • MDR-1 status (macrocyclic lactones)
  • sedation (Amitraz)
  • Local irritation (Goodwinol)
  • Stink/staining (Lime sulfur)
  • secondary dz associations - Pemphigus f., species concerns
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10
Q

What’s a good way to remember which heartworm preventives are microfilaricidal?

A

if their generic names start with “m” (moxidectin, milbemycin), they are microfilaricidal

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11
Q

How do you treat scabies?

A
  • Ivermectin (PO, daily)
  • Selamectin (topical q2 wks, DOGS)
  • Lime sulfur (weekly dips) - significant antipruritic effect
  • Flumethrin (collar) - “aids in treatment”
  • Moxidectin (w/ imidacloprid) - weekly topical
  • Fipronil (off label usage q2 wks)
  • -laners (avoid in epileptics)
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12
Q

What are some considerations to have with flea control?

A
  • Environmental control
  • Life stage being controlled
  • No other animals moving in/out of environment
  • Requires 3-6 months of GOOD environmental (including ALL pets in household) treatment to control an environment
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13
Q

How long do topical flea treatments take to reach a steady state?

A
  • 5-6 months after starting monthly application
  • Applying topical more frequently does NOT achieve a HIGHER steady state, but does achieve steady state a bit SOONER
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14
Q

How do you treat the environment for flea control?

A
  • treat ALL animals in house
  • treat/wash the bedding/furniture/carpets
  • treat shaded to daylight areas of the year (PHOTOPHOBIC)
  • ”Flea bombs” are treating a lot of area that fleas do not get to
  • It takes 3-6 months to control an infested environment
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15
Q

How do fleas develop resistance?

A
  • All/most fleas in genetic population must be exposed to the same insecticide consistently (closed environment)
  • no/few hosts in environment that are NOT treated
  • no/minimal refugia
  • +/- duration of potential exposure (older products)
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16
Q

How do fleas develop refugia?

A
  • Individuals that were not exposed to the same insecticide that reintroduce novel genetic material to a given population
  • Prevents development of resistance
17
Q

What are some adulticides for flea control?

A
  • Imidocloprid
  • Fipronil
  • Spinosad/Spinetoram (seizures)
  • Nitenpyram (only 24 hours)
  • Dinotefuran (smells like garlic, neurotoxic effect)
  • Cyphenothrene (pyrethroid)
  • Laners (seizures)
  • Indoxacard (metabolized by liver of flea)
  • Flumethrin
  • Permethrin - toxic to cats/fish
18
Q

What are some examples of Insect Growth Regulators?

A
  • Impairs molting of larval stage to pupa
    • Pyriproxygen
    • Methoprene
    • Imidocloprid
    • Flumethrin
  • Weakens egg wall, impairs egg to larval maturation
    • Lufenuron - sterilized adult for 60-90hrs
19
Q

How do you kill ticks?

A
  • Amitraz - effective for 3 months (collar, topical)
    • be careful with Promeris (off the market but REALLY high concentration - PF)
  • Fipronil - effective for 3 months (topical)
  • Selamectin - effective for 1 month (topical- DOGS only)
  • -Laners - effective for 1 month (except Fluralaner - 12 weeks, 8 wks Lone star tick)
    • all oral
20
Q

What are some examples of tick repellants?

A
  • Pyrethroids
    • Cyphenothrin - topical
    • Flumethrin - collar, effective for 5-8 mo
    • Deltamethrin - collar, effective for 6 mo
  • Permethrin

ALL TOXIC TO CATS AND FISH

21
Q

How do you treat ear mites?

A
  • Ivermectin - SQ in single high dose (BURNS)
  • Topical
    • Ivermectin single dose
    • Selamectin q2wks x 3
    • Milbemycin single dose
    • Moxidectin q2 wks x 3
    • Fipronil q2wks x 3
    • Tresaderm q24h x 7d (anecdotal)
  • PO
    • Laners
22
Q

What are some concerns you might have regarding ear mite treatment?

A
  • Ivermectin
    • BURNS SQ
    • INTACT EAR DRUM
    • HW NEG IF INJECTION
    • DO NOT USE SQ IN MDR1 DEFICIENT DOGS
  • Heartworm microfilaricidal - macrocyclic lactones
  • Ear cleaning
23
Q

How do you treat lice?

A
  • Fipronil (at flea dose/strength and frequency)
  • Flumethrin collar
  • Imidacloprid (not approved)
  • Selamectin (not approved)
  • Most flea prev

all topical treatments should be given q30d x 2

24
Q

How do you treat Cheyletiella (walking dandruff)?

A
  • No approved tx
    • Selamectin topically q14d x3
    • Ivermectin SQ or PO q14dy x 3
    • Fipronil spray
    • Lime sulfur dip weekly
    • Permethrin - topically q14d
    • Amitraz dip weekly
    • Very contagious, zoonotic
25
Q

How do you treat Chiggers?

A
  • No approved tx
    • Fipronil topically
    • Permethrin (dog only)
    • anti-inflamm or antihistamines recommended to control pruritus