Ecotoxicology Flashcards
What is a toxicant?
chemical that has an effect on an organism
What is a toxin?
substance produced by a living organism which is poisonous at a certain level
What does hydrophobic mean?
substance that repels water or will not dissolve in water
What does hydrophilic mean?
substance that will easily dissolve in water
What does xenobiotic mean?
man-made chemical found in a biological system that is not naturally found there
What is poison?
substance that can cause biological disturbances to a living organism at a certain dosage
What is a dose?
quantity of drug to be administered all at one time or over a given period of time
What makes a chemical poisonous?
the dosage
- Lethal Dose Fifty (LD50) is one way the _____ of chemicals are measured.
- What is LD50?
- How is LD50 measured?
- toxicity
- amount of a toxicant required to kill half (50%) of a population
- mg of toxicant/kg of animal’s body weight
- What is Lethal Concentration 50 (LC50)?
2. How is LC50 measured?
- Concentration of a toxicant in an environment which produces death in 50% of a population
- mg of substance/L of air or water
- What is Toxic Dose 50 (TD50)?
- The _______ the TD50, the more toxic the chemical is.
- What does NOEL stand for and what does it mean?
- dosage that produces toxic effects in 50% of the population
- lower
- No Observable Effect Level: highest dose of a toxicant that produces no noticeable toxic effect on animals
What are the three ways chemicals can enter the body?
- Ingestion
- Inhalation
- Absorption
The skin is a major barrier that protects agaisnt chemicals. What is its main layer of defense?
Stratum corneum
- What is the stratum corneum?
2. Why is it used as a defense agaisnt chemicals?
- Thick layer of dead and flattened skin cells
2. Water-proof, contains the protein keratin which allows for protection agaisnt damage
What do the kidneys do to prevent toxicity?
Allows toxicants to be excreted via the urine