Eating Disorders Flashcards

1
Q

List the main features of anorexia nervosa:

A

Weight loss (or lack of weight gain in context of children) - body weight >15% below normal

  • Weight loss is self induced by avoidance of “fattening foods”
  • Self perception of being too fat / fear of fatness
  • Widespread endocrine disorder involving the hypothalamic-pituitary-gonadal axis
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2
Q

What can happen if a young girl has anorexia prior to pubertal onset?

A

Breasts will not develop
Amenorrhoea
(in boys genitals will remain juvenile)

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3
Q

Will females who suffer anorexia before puberty, start puberty post recovery?

A

Yes

Menarche will be delayed

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4
Q

What is the ICD-10 criteria for bulimia nervosa?

A
  • Recurrent episodes of overeating - large amount consumed in short time
  • Persistent preoccupation with eating and strong desire/compulsion to eat
  • Patient attempts to counteract fattening effects of food
  • Self perception of being too fat, with n intrusive fear of fatness
    (tend to be underweight)
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5
Q

What mechanisms will someone who suffers from bulimia nervosa use as a way of counteracting their food’s fattening effect

A

Self induced vomiting
Self induced purging
Alternating periods of starvation
Abuse of laxatives/diuretics etc

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6
Q

What is the DSM V criteria for binge eating disorders (BED)

A
  • Recurrent episodes of binge eating
  • A sense of a lack of control over eating during the episode
  • Marked distress regarding the binge eating
  • Binge eating occurring once a week for 3 months at least
  • NOT associated with inappropriate compensatory methods like bulimia nervosa
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7
Q

How are binge eating episodes defined according to the DSM V criteria?

A

Three or more of the following:

  • eating more rapidly than normal
  • eating until uncomfortably full
  • eating alone out of shame
  • feeling disgusted, depressed or guilty post-binge
  • eating large amounts of food despite not feeling hungry
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8
Q

List a few clinical signs specifically associated with bulimia nervosa:

A
Dental caries 
Russel's sign
Enlarged parotid glands
Oedema (from laxative/diuretics)
Abnormal ECG
Cardiomyopathy
Tetany
Gastric Dilation
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9
Q

List some of the symptoms of bulimia nervosa:

A
Fatigue
Lethargy
Feeling bloated
Cardiac arrhythmias 
Constipation
Abdo pain
Abnormal menstruation
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10
Q

List some of the symptoms commonly seen in anorexia nervosa specifically:

A
Fatigue
Decreased sleep cycle
Sensitive to cold
Dizziness
Fullness after eating very little
Dry skin
Brittle hair
Lanugo hair (fine down)
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11
Q

What are some neurological symptoms associated with anorexia nervosa?

A

Decreased visio-spatial ability
Decreased visual memory
Increased speed of processing
Peripheral neuropathy

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12
Q

List some of the red flags in anorexia nervosa;

A
BMI <13
Weight loss >1kg / week
Core temp <34
Prolonged QT, HR <40
Systolic BP <80
Cognitive impairment
Inability to rise from squat without using arms
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13
Q

What investigations should be done for patients with eating disorders:

A
ECG
Us and Es
WCC (low)
Iron levels, 
LFTs - ALT and GGT will be deranged if liver breakdown is occurring
DXA scan
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14
Q

What changes can occur to the brain when starved?

A
  • Loss fo grey and white matter
  • Increased compulsive behaviour
  • Reduced social skills
  • New learning is stunted
  • Poor concentration and decision making
  • Enhanced response to hedonic and nutrostat signals
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15
Q

What is refeeding syndrome?

A

A potentially fatal condition caused by rapid initiation of food after >10 days of undernutrition.

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16
Q

What are some of the signs of refeeding syndrome?

A
Rhabdomyolysis
Resp or Cardiac failure
Drop in BP
Arrhythmias
Seizures
Sudden death
17
Q

How do you prevent refeeding syndrome?

A

Frequnet blood monitoring

Slow pace of initiating food

18
Q

Why does refeeding syndrome occur?

A

The body begins to repair itself so it uses up the available food sources too quickly, then begins to use inadequate stores of other nutrients, causing breakdown of organs. (Mg, K, PO- etc)

19
Q

What bloods should you monitor for refeeding syndrome- what is worrying?

A

Phosphate levels -decreasing
Magnesium - increases
Glucose - increases
Potassium -decreases

20
Q

1/5 patients with anorexia die from _______

A

Suicide

21
Q

List some risk factors for developing an eating disorder:

A
Depression
OCD
Diabetes mellitus 
Substance abuse 
Serotonin dysregulation
Adverse life events 
Feeding problems in childhood
Family history
22
Q

What are some treatment options for patients with anorexia nervosa?``

A

CBT
<18 y/o - family therapy
Medication for co - morbidities
Olanzapine can stimulate appetite (not licensed)

23
Q

What medication can be used in the treatment of bulimia nervosa?

A

Antidepressants - decrease binging episodes and purging

SSRIs are first line (esp. fluoxetine)

24
Q

List some metabolic complications of eating disorders?

A
Hypothermia
Dehydration
Electrolyte disturbances
hypoglycaemia
LFT derangement
25
Q

A BMI of 14.9-13 is considered _____ risk?

A

High

26
Q

A BMI of _____ is considered very high risk:

A

<13

27
Q

A BMI of ________ is considered low risk of an ED:

A

17.5 - 16

28
Q

What other features are used to measure the risk of the patient with an eating disorder?

A
  • Rate of weight loss
  • Blood results
  • Circulation
  • Muscle strength
  • Temperature
  • ECG abnormalities