Eating Disorders Flashcards

1
Q

Eating Disorders (Defined)

A
  • serious, life-threatening, multi-determined illnesses that require expert care
  • really about patient’s thoughts that they have about food and disordered eating. It’s a spectrum of things (just because someone comes in and doesn’t look like they have an eating disorder, doesn’t meant they don’t have one.
  • can serve as an expression of psychological states and needs
  • evidence suggests that these illnesses are neurobiologically-based and NOT diseases of choice

-often times people have comorbidities like anxiety and stress

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2
Q

Epidemiology of Eating Disorders

A

-Up to 30 million people (all ages and genders) suffer from this

-AN has the HIGHEST MORTALITY RATE of any mental illness (1 in 5 individuals commit suicide)
Research suggests that the decreasing mortality due to AN is a result of more specialized treatment units
-23% of individuals with BN die as a result of suicide
Obesity: especially morbid obesity, is associated with an increased risk for mortality, however, net effect is difficult to quantify

  • 3rd most common chronic condition in adolescent females (3-12% of adolescents experience some form of eating disorder)
  • increased attention is beginning to be paid to: (minority women, males, children and older individuals [particularly pregnant women who feel they need to lose weight], LGBTQ)
  • 1 out of 10 people with an eating disorder is male
  • only 35% seek treatment from a facility that specializes in eating disorders
  • 42% of 1st-3rd girls want to be thinner (important)
  • 42% of young women with anorexia is 12x’s more likely to die rather than other women her age without anorexia

Dieting may be the gateway. You might have a genetic predisposition for an eating disorder, then you have stress (external thing going on)< try dieting and brain gets more malnourished (91% of women on college campus had attempted a diet)

-5-10% of anorexics die within 10 years
18-20% die within 20 years
50% report ever being cured

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3
Q

Prevalence of Eating Disorders

A

AN: 0.5-1% among females in late adolescence, early adulthood

BN: 1-3% among females in late adolescent/early adulthood

Subclinical ED prevalence estimates as high as 13% in population

-ED prevalence similar among Non-Hispanic Whites, Hispanics, African-Americans, and Asians in US (exception is AN, more common among non-Hispanic weights)

Most common eating disorder: BINGE EATING DISORDER

  • higher proportion of males here. Have about 4 in 10 males with this disorder in particular
  • 2.8% of the US adult population
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4
Q

Importance of Screening and Early Detection

A

-delay in appropriate EDO-focused treatment results in: numerous medical, psychological, and social complications (some of which, not all, are completely reversible)
Long lasting implications on development
-The longer the EDO persists, the harder it is to treat
-crude mortality rate for AN is 4-5% (higher than any other psychiatric disorder)
-costs for AN treatment and quality of life indicators: if AN progresses into adulthood-rivals that of schizophrenia

e.g. Osteoporosis is an irreversible effect of AN. We can prevent it from getting worse but we can’t get back bone mass. Debatable in adolescence because peak bone may still be developing.

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5
Q

Classification of Eating Disorders

A

AN
BN
Binge Eating Disorder (BED)
Avoidant/Restrictive Food intake Disorder (people fail to have enough nutritional intake and it may be related to a med illness like Crohn’s, can develop into a fear of food or aversion related to that pain)
Other specified feeding and eating disorders (OSFED)
Atypical AN (we see more higher weight individuals that demonstrated fear of weight gain and may lose a significant amount of weight and even though they’ve lose all this weight, they remain normal due to high starting baseline)
Subthreshold BN
Subthreshold BED
Purging Disorder (vomiting only as a mechanism to undo intake)
Night Eating Syndrome

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6
Q

AN Diagnostic Criteria

A
  • restriction of energy intake relative to requirements result in in low weight
  • intense fear of gaining weight or interference in gain
  • disturbance in weight or shape experience, excessive influence self-evaluation, or lack of recognition of seriousness of low weight
  • severity levels: goes by BMI. (Mild is >17, Moderate is 16-16.9, Severe is 15-15.9 and extreme is <15).
  • sometimes we give anti-psychotics because of this deep distortion of body perception
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7
Q

AN (subtypes)

A

Restricting Type: during the current episode of AN, the person has not regularly engaged in binge-eating or purging behavior

Binge-Eating/Purging Type: during the current episode of AN, the person has regularly engaged in Binge-eating or purging behavior (i.e. Self-induced vomiting or the misuse of laxatives, diuretics, or enemas)

  • –main difference from Bulemia is that patients are almost always going to be underweight. Buliemia patients tend to be normal weight or overweight
  • Amenorrhea is NO longer included in criteria
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8
Q

Common Clinical Presentations of AN

A
  • intense preoccupation with thoughts of weight, shape, size and food, irrational worries about fatness
  • frequently look in mirrors, focuses on appearance, likely body checks
  • may hide food, spend a large amount of time cutting up food into small pieces, rearranging food on plate to eat less
  • may collect recipes, cook/bake for others
  • losing weight boosts self-confidence through fueling perfectionistic traits common in restricting subtype
  • delayed psychosocial development and decreased interest in sex
  • denial, resistance to treatment, core feelings of inadequacy and ineffectiveness (resistance common barrier to research)
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9
Q

Binge Eating

A

-can occur across the spectrum of eating disorders AND other disorders

  • rapid weight loss is bad for growing children
  • assessment can be difficult due to age/development. Patient must have abstract reasoning skills, perspective taking skills and ability to label emotions
  • key here is the LOSS OF CONTROL. We can really see it happen across spectrums of illnesses. WE Scan see it in general developmental obesity

-often consume very high caloric, high fat items. Large volumes of foods in small amount of time. Several thousand calories at a time

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10
Q

Binge (definition)

A

1: eating, in a discrete period of time (e.g within any 2 hour period), an amount of food that is definitely larger than most people would eat during a similar period of time and under similar circumstances
2: a sense of lack of control over eating during the episode (e.g. A feeling that one can’t stop eating or control what or how much one is eating)

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11
Q

Bulimia Nervosa (diagnostic criteria)

A
  • recurrent episodes of binge eating
  • recurrent inappropriate compensatory behaviors to prevent weight gain (misuse of laxatives, self-induced vomiting, diuretics, enemas, fasting, exercise
  • Binge and purge episodes occur on average once per week for 3 months
  • self-evaluation is unduly influenced by shape/weight
  • the disturbances does not occur exclusively during episodes of AN
  • categorized severity based on number of episodes of compensatory mechanisms per week (i.e. Mild average of 1-3 severe avg. of 14+)
  • tend to be normal or overweight
Purging Methods:
    Self-induced vomiting
    Laxative abuse
    Diuretic Misuse 
    Enemas
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12
Q

Common Clinical Presentation-BN

A
  • more prevalent in females
  • usually in normal weight range, can be overweight
  • frequently experience weight fluctuations
  • sense of losing control is significant
  • abdominal pain/discomfort, self-induced emesis, sleep or social interruption usually ends bulimic episode—-feelings of guilt, depression, self-disgust follow
  • have fear of not being able to stop eating voluntarily
  • often fast eater
  • often experience difficulties with satiety system-extreme hunger then lose control and binge, may feel full after end of normal meal
  • food consumed usually high caloric and texture easy to eat quickly
  • experience difficulty feeling full after end of normal meal
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13
Q

Binge Eating Disorder (diagnostic criteria)

A
  • these individuals shave episodes with sense of lack of control. Don’t have a significant amount of compensatory mechanisms
  • in general: it’s binge eating without other ways to undo things. Eat a lot of food when they’re not hungry. Eat alone. Feel guilty and a lot of distress
  • recurrent episodes of binge eating
  • binge Eating episodes are associated with at least 3:
    1: Eating much more rapidly than normal
    2: eating until feeling uncomfortably full
    3: eating large amounts of food when not physically hungry
    4: eating alone because of embarrassment
    5: feeling disgusted with oneself, depressed or very guilty after overeating
  • marked distress regarding binge eating
  • at least once a week for 3 months
  • no recurrent use of inappropriate compensatory behavior
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14
Q

Clinical Presentation: BED

A
  • most common eating disorder in males
  • obesity, including severe obesity in 50% of patients (BMI >40), most patients/subjects with BED are overweight or obese but can be of normal weight
  • 30% of individuals in weight-loss programs have BED
  • 25% to 50% of patients seeking bariatric surgery have BED
  • Experience many other psychiatric and physical illnesses including metabolic syndrome
  • patients with BED commonly ask for help with depression or weight gain rather than binge eating per se
  • BED symptoms often increase during stress
  • experience body image concerns too
  • these patients tend to be the most motivated. They move forward and work hard usually. Don’t see much denial as opposed to those with anorexia
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15
Q

BN vs. BED

A

BN:

  • binge eating, often episodes more severe
  • compensatory behavior
  • over concerned with shape/weight
  • once/week for 3 months
  • generally in normal weight range

BED:

  • binge eating
  • absence of compensatory behavior
  • indicators of loss of control (binge eating)
  • marked distress, often with weight/shape concerns
  • once/week for 3 months
  • generally in overweight or obese range
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16
Q

Comorbidity With Eating Disorders

A

-depression/mood challenges: 33-50% in AN, nearly 50% in BN and nearly 50% in BED
-Anxiety disorder (OCD, GAD, Panic, PTSD)
-alcohol and other substance abuse disorders are 4 times more (they struggle with this)
-Personality Disorders
-non-suicidal self-injury
-suicidal ideation and attempts:
Occurs across the spectrum of disorders
1 in 5 deaths in AN related to suicide
-(IMPORTANT): acute effects of malnutrition impact mood and anxiety AND eating disorder behaviors often serve to manage mood/anxiety for patients albeit temporarily

17
Q

Etiology of Eating Disorders (multifactorial)

A
  • Biology/genetics
  • psychological traits/temperament
  • social/ENV factors

Treatment needs to focus on these 3 areas

18
Q

Predisposing genetic factors-AN

A

-family studies: female relatives of someone with an ED have greater than 4x’s risk of BN and greater than 11x’s risk of AN than someone with no family history (probably higher for subclinical and partial syndromes)
-twin studies: AN has estimated heritability of 58-76%, BN from 31-83%
-these heritability estimates are in line with those of Major Depression, Bipolar Disorder and Schizophrenia
-Heritability estimate for breast CA is about 27%
O

19
Q

Biological Perpetuation Factor of Starvation

A

40 healthy male volunteers
-3 months observation
-6 months semi starvation (emotional and personality changes like depression, irritability, apathy, obsessionality) and preoccupation with food, food hoarding, binge eating, Altered taste/preferences
-3-9 month re feeding and observation
-2months to 2 years to return to baseline
(The brain does get more stuck, depressed, anxious when it’s malnourished. Pure reality of restricting intake caused them to have these challenges. It took a decent amount of time, much longer than the time they were starved, to recover)

  • low body weight and dieting can result in eating disorder behavior and thinking
  • treatment goal is to normalize weight before we can expect to normalize behavior and thinking
20
Q

Psychological Predisposing Factors for EDs

A
  • perfectionism
  • OCD
  • neuroticism
  • negative emotionality
  • harm avoidance
  • core low self-esteem
  • avoidant personality disorder traits
  • specific additional personality traits may be associated with each type of eating disorder
  • prolonged starvation induces change in cognition, behavior, and interpersonal characteristics
21
Q

Sociocultural Factors for EDs

A

dieting:
-dieters at 5 year follow up were at significantly higher risk for ED behaviors and at greater risk of obesity
-in another study, dieters were 5x’s more likely to develop an ED, severe dieters 18x’s
-caloric restriction combined with stress produces binge eating in animals
Transitions, loss
Violence or abuse
Western ideals of thinness
Parent-child interactions
Family structure
Ethnicity
Conflict between traditional and modernizing roles for women
Peer influence: sororities, sports (dancers, gymnasts, wrestlers, jockeys)
Media

22
Q

Screening for EDs

A
  • asking about nutrition and appetite is IMPERATIVE
  • the process starts with us: if we don’t ask, we will not have the opportunity to know
  • many people express concern about weight and diet inappropriately, and don’t have an EDO
  • many people with an EDO will attempt to hide the disorder (a denial of the illness doesn’t indicate an absence)

Can use Modified ESP (Eating Disorders Screen in Primary Care)

Take note of:

  • excessive weight concern
  • inappropriate dieting
  • pattern of weight loss
  • primary or secondary amenorrhea
  • in children/adolescents, failure to achieve appropriate increases in weight or height

If suspicion of eating disorders is raised:

  • establish the diagnosis
  • evaluate medical and nutritional status
  • determine severity
  • perform initial psychosocial evaluation
23
Q

Medical Workup

A

Key guidelines:

  • acute malnutrition is a medical emergency
  • eating disorders are serious mental illness with significant, life-threatening medical and psychiatric morbidity and morality (regardless of an individual’s weight)
  • Anorexia Nervosa: has the highest mortality rate of any psychiatric disorder

Hx:

  • weight changes and frequency of weighing self
  • 24 hour food recall
  • where he or she eats, and with whom
  • purging: modes-self induced vomiting, laxatives, diuretics, fat absorbers, enemas, exercise
  • use of diet pills and/or caffeine
  • exercise/movement: compulsive component
  • binging, night eating, compulsive eating, and/or grazing
  • Orthorexia themes (drive for eating foods that one considers healthy)
  • use of other meds (stimulants, insulin, thyroid hormone)
  • body image
  • body checking and comparison
  • for BED: complications of obesity
  • psychiatric, medical, menstrual, fertility, family, development and social histories
  • ROS

Vitals:

  • BP and Pulse (orthostatics initially)
  • Temperature
  • Height
  • Weight (gowned vs. not gowned)

Lab Monitoring:

  • baseline screening labs: CBC with diff, CMP, Mg, Phosphorus, Thyroid profile, UA, Vitamin D 25-OH
  • total testosterone level in males
  • pregnancy test (amenorrhea does not EQUAL infertility)
  • urine drug screen
  • DEXA scan as clinically indicated
  • EKG
  • fasting lipid panel (HbA1C): for BED patients, those on atypical antipsychotics
  • can see some changes in WBC in anorexia, metabolic profile that looks at kidney and liver function. These people can have low potassium, elevated Bicarbonate (bulimia in particular)
  • normal lab results doesn’t exclude serious illness or medical instability in these patients
24
Q

Anorexia Affects your whole body

A

Brain and Nerves: can’t think right, fear of gaining weight, sad, moody, irritable, bad memory, fainting, changes in brain chemistry

Hair: gets thin and brittle

Heart: low BP, slow HR, fluttering of heart, heart failure

Blood: anemia and other blood problems

Muscles and Joints: weak muscles, swollen joints, fractures, osteoporosis

Kidneys: kidney stones, failure

Body fluids: low potassium, Mg and Na

Intestines: constipation and bloating

Hormones: periods stop, bone loss, problems growing, trouble getting pregnant. if pregnant, higher risk for miscarriage, having a C-section, baby with low birthweight and post-partum depression

Skin: bruise easily, dry skin, growth of fine hair all over body, get cold easily, yellow skin, nails get brittle

25
Q

Bulimia Affects on your body

A

Brain: depression, fear of gaining weight, anxiety, dizziness, shame, low self-esteem
Cheeks: swelling and sore
Mouth: cavities, tooth enamel erosion, gum disease, teeth sensitive to hot and cold foods
Throat and Esophagus: sore, irritated, can tear and rupture, blood in vomit
Muscles: fatigue
Stomach: ulcers, pain, can rupture, delayed emptying
Skin: abrasion of knuckles, dry skin
Blood: anemia
Heart: irregular heart beat, heart muscle weakened, heart failure, low pulse and BP
Body Fluids: dehydration, low K, Mg, Na
Intestines: constipation, irregular bowel movements, bloating, diarrhea, abdominal cramping
Hormones: irregular or absence period

Lab findings:
Hypokalemic and hypochloremic alkalosis