eating disorders Flashcards

1
Q

prevalence of EDs in males

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

Study: 5.5% of males manifest elevated ED risk (USA)

Lifetime prevalence in DSM-5 (male dutch sample): 1.2%

Existing prevalence rates likely underestimate the number of males affected by EDs, as the social stigma associated with ED pathology in males often causes them to minimize or deny the presence of symptoms

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2
Q

male ED symptom presentation

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

males generally report less shape and weight concern, drive for thinness, and body dissatisfaction than their female counterparts
- male concerns typically center around being “bigger” and more muscular

Muscle dysmorphic disorder: describes individuals who have a preoccupation with their appearance and are concerned that they are not sufficiently large and muscular
- Often engage in activities intended to enhance muscularity - including dieting, weightlifting, and steroid drug use

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3
Q

sex differences in symptoms

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

Males who present with bulimic symptoms are less likely to engage in dieting, laxative use, and self-induced vomiting than females

Males less likely to report eating in response to negative emotion, experiencing a sense of loss of control when binge eating, and restricting their food intake in response to body dissatisfaction

Mixed findings regarding excessive exercise - some find women do it more, other do not

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4
Q

assessment of ED

eating disorder examination (EDE)

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

considered the “gold standard” for the assessment of EDs

Semi-structured diagnostic interview

4 subscales: dietary restraint, eating concern, shape concern, weight concern

Assess the frequency and intensity of behavioral and cognitive symptoms associated with EDs during the last 28 days (last 3 months for diagnostic items)

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5
Q

assessment of ED

self report questionnaires

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

several diff ones

may yield less valid data in comparison to semi-structured diagnostic interviews like the EDE
- Latter provides an opportunity for an evaluator to explain the meaning of terms

Contemporary ED measures created & normed predominantly for female populations → major criticism is their overreliance on items that capture stereotypically feminine indicators of ED pathology

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6
Q

treatment strategies

family based behavioral treatment

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

is the only intervention that has been delineated as a well-established treatment for adolescents with EDs

For young adults: CBT & interpersonal psychotherapy are the most established treatments

Compared to females, young adult males are less likely to seek treatment for EDs + do so later relative to the onset of their eating pathology - several reasons:
- may not be aware that their behaviors are pathological
- health care providers less likely to recognize disorderd eating
- shame and stigma

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7
Q

treatment strategies

factors that can enhance treatment outcomes for ED males

Limbers (2018)

Eating disorders in adolescent and young adult males: prevalence, diagnosis, and treatment strategies

A

Improving interpersonal interactions has been identified as an important target in ED treatments for males

Therapist characteristics and quality of therapeutic relationships were the most critical factors in the treatment experience of males in ED treatment

Trust and comfort in a therapist were the most critical components of ED treatment for males

Weight history, sexual abuse, trauma, sex orientation, body image, exercise abuse, media pressures, and the interplay of depression, EDs, and shame are additional topics that are important to cover in ED treatment with males

Males with EDs have reported that male-only treatment groups help them to feel less isolated than predominantly female groups

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8
Q

epidemiology

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Pediatric EDs are more common than type 2 diabetes, and the epidemiology is changing, with higher rates of EDs in younger children, boys, and minority groups

Most adolescents diagnosed with other specified feeding or eating disorder OSFED (previously EDNOS)
- = a group of heterogeneous disorders composed primarily of subthreshold AN or BN
- Lifetime prevalence: 4.8%

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9
Q

etiology

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

The exact etiology of EDs is unknown - thought to be an interface between genetic and biological predispositions, environmental and sociocultural influences, and psychological traits

Evidence continues to increase that EDs are heritable - relatives of ED patients having 7 to 12x greater risk of developing an ED

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10
Q

clinical presentation in children and adolescents

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

The physical and cognitive development that occurs during adolescence lends itself to substantial differences in the presentation of EDs in children and adolescents

An ED should be suspected in a patient of any weight who presents with:
- weight loss
- unexplained growth stunting or pubertal delay
- restrictive or abnormal eating behaviors
- recurrent vomiting
- excessive exercise
- trouble gaining weight
- body image concerns

Younger patients are likely to have atypical presentations - e.g. instead of rapid weight loss, they may present with failure to make expected gains in weight or height and may not endorse body image concerns or engage in binge eating or purging behaviors

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11
Q

medical complications

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

EDs can affect every organ system, and complications can occur at any weight

can affect:
- cardivascular system
- gastrointestinal complication
- electrolyte disturbances
- other physical complications: endocrine, renal, hematologic, neurologic

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12
Q

psychiatric comorbidities

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

are common in EDs but may be premorbid, comorbid, or present after recovery

common comorbidities: depression, anxiety, OCD, PTSD, personality disorders, substance abuse disorders, and self-injurious behaviors

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13
Q

treatment

treatment threshold

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Treatment threshold for ED adolescents should be low because of potentially irreversible effects of EDs on growth and development, their mortality risk, and evidence that early treatment improves outcomes

Children and adolescents are triaged to outpatient treatment, partial hospitalization, residential programs, and inpatient hospitalization - based on severity of illness, duration of disease, safety considerations, and familial preferences

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14
Q

treatment

evidence for efficacy

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Evidence for effective treatments in EDs in children and adolescents is growing but remains limited

Primary treatment modalities in pediatric AN are: individual therapy, CBT, and FBT
- FBT has the largest evidence base of any treatment of efficacy in adolescent and young adult AN populations with multiple clinical trials

CBT has been studied in adolescents with BN and shows promise - but there is growing evidence that FBT is also effective
- CBT has also demonstrated efficacy in BED

In subthreshold disorders, it is recommended that the patient be treated based on the full syndrome to which their disorder is most similar

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15
Q

treatment

family-based treatment

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Caregivers are not blamed but instead empowered to refeed their child back to health

The disorder is externalized from the child to release blame toward the child for their disorder

FBT progresses through 3 phases that target the goals of treatment in children and adolescents with EDs: physical, behavioral and psychological recovery
1. Phase 1: focuses on coaching the caregivers to refeed their child to recovery through specific therapeutic interventions
2. Once weight is restored → Phase 2: focuses on gradually transferring developmentally appropriate control of eating back to the patient
3. Phase 3: works on relapse prevention and any other remaining developmental considerations, and then treatment termination

Typically conducted over a 6-12 month period

Patients in FBT achieve full remission within 1 year, another 25% to 35% partially recover (showing improvement but not full remission), and only 15% are nonresponsive to treatment

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16
Q

treatment

pharmacotherapy

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Pharmacologic agents are often used in patients with EDs, despite few studies demonstrating efficacy

There have been no published randomized controlled trials (RCTs) for antidepressant treatment in AN conducted in children and adolescents

SSRIs and TCA have not been shown to be better than placebo in weight gain or improvement in ED symptoms in adult AN

In BN, several RCTs in adults have found that antidepressants are effective in decreasing binge eating and purging symptoms

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17
Q

prevention

Campbell & Peebles (2014)

Eating Disorders in Children and Adolescents: State of the Art Review

A

Developing effective primary and secondary prevention efforts is critical in EDs because of their high rate of future medical complications, psychiatric comorbidities, and risk of suicidality and relapse

Features of successful ED prevention programs:
- Target high risk adolescents over 15 y of age
- Deliver intervention by trained individuals
- Intervention content should include body acceptance and dissonance induction

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18
Q

enhanced model of CBT (CBT-E)

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

Model of CBT was revised & extended by Fairburn (2008)→ enhanced behavior therapy (CBT-E)

Major change from og treatment: the reformulation of it as an intervention not specifically for BN but for all eating disorder psychopathology

= CBT-E is a transdiagnostic treatment → focuses on the common processes that maintain different forms of eating disorder psychopathology

Treatment planning is guided by personalized treatment formulations

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19
Q

2 versions of CBT-E

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

A ‘focused’ treatment (CBT-Ef) - very similar to the earlier version but has 2 main changes:
1. it details a revised strategy and methods for addressing overvaluation of body weight and shape
2. it provides an explicit treatment module for what is called “mood intolerance” as a specific trigger of binge eating and purging

A ‘broad’ treatment (CBT-Eb) - based on a broader model of the problems (comorbid disorders) that are widely believed to maintain eating disorders or at the very least complicate their treatment

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20
Q

CBT for bulimia

aims

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

targeted at eliminating the psychopathological processes that maintain the disorder - aims to:
- Replace dysfunctional dieting with a regular and healthy pattern of eating
- Cease purging and other extreme forms of weight control
- Decrease over evaluation of body shape and weight

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21
Q

CBT for bulimia

treatment efficacy

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

study: compared CBT-EF with psychoanalytic psychotherapy in treatment of BN
- After 5 months 42% of CBT-E patients had completely ceased binge eating and purging versus only 6% of those in the psychoanalytic psychotherapy condition
- At the 2-year point the respective numbers of patients in remission were 44% for CBT-E and 15% for psychoanalytic psychotherapy

study: comparison of CBT-E with interpersonal psychotherapy
- Main result at post-treatment was that 65.5% of CBT-E patients were in remission versus 33.3% of IPT patients
- CBT-E patients: 2x the amount of patients reported no binging or purging compared to IPT

Conclusion: both studies showed that CBT-E was significantly more efficacious in treating EDs than the comparison treatment

22
Q

CBT for bulimia

predictors and moderators

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

In general robust predictors or moderators of treatment outcome in the treatment of BN have yet to be identified

Exception to this: early response to treatment - showed that what has been called an early response to CBT (in this case a significant reduction in purging by week 4) was a strong predictor of outcome at post-treatment
- rapid response also clinically sig predictor for treatment outcome in BED

23
Q

CBT for bulimia

guided self-help

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

Guided self-help based on the principles & procedures of CBT (CBTgsh): combines a self-help manual with a limited number of brief therapy sessions

Prior reviews are consistent in showing that CBTgsh can be an effective intervention for BN as compared with a minimal control condition such as a waiting list

24
Q

CBT for BED

therapeutic efficacy

Wilson (2018)

Cognitive-Behavioral Therapy for Eating Disorders

A

Consistently shown that manual-based CBT produces remission rates in binge eating between 50% and 70% that are generally well maintained at follow-up

Research has shown the manual-based CBT is more effective overall than BWL (behavioral weight loss treatment)

CBT vs pharmacotherapy: greater (longer-term) efficacy of CBT

25
# CBT for BED guided self help | Wilson (2018) ## Footnote Cognitive-Behavioral Therapy for Eating Disorders
Study: at 2-year follow-up, both CBTgsh and IPT not only successfully maintained their improvement, but were also significantly superior to BWL in producing remission from binge eating - Results provide further evidence that CBT is more effective than BWL in eliminating binge eating in overweight and obese patients
26
# CBT for anorexia therapeutic efficacy | Wilson (2018) ## Footnote Cognitive-Behavioral Therapy for Eating Disorders
studies encourage the further development and application for CBT-E as a treatment for adults and adolescents with AN - adolescent CBT completers showed significant improvement in eating disorder psychopathology and weight gain - adult completers showed substantial improvement in weight and eating disorder psychopathology at post-treatment another study found disappointing results: on almost all other measures TAU did comparably well + CBT-E did not improve on TAU on any measure of efficacy
27
effectiveness and scalability of CBT | Wilson (2018) ## Footnote Cognitive-Behavioral Therapy for Eating Disorders
- efficacy: short & long term results - cost effective - clinical range/reach: transdiagnostic nature offers major advantages - brevity: breif treatment is advantageous - task sharing: currently minimal evidence on use of this in ED treatment - scalability: capacity of CBT to “scale up” treatment so as to provide greater access to treatment for large numbers of people
28
interpersonal theory | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
Hypothesizes that interpersonal functioning is a critical component of psychological adjustment and well-being IPT acknowledges a **two-way relationship between social functioning and psychopathology**: - Disturbances in social roles can serve as antecedents for psychopathology - And mental illness can produce impairments in the individual’s capacity to perform social roles **IPT makes no assumptions about the causes of psychiatric illness** - however, it assumes that the development and maintenance of some psychiatric illnesses occur in a social and interpersonal context + that the onset, response to treatment, and outcomes are influenced by the interpersonal relations
29
interpersonal model for EDs | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
Suggests that **problems with social functioning cause difficulties with low self-esteem and negative affect, which then lead to binge eating behaviors** This is supported by data - EDs have been consistently associated with poor interpersonal functioning Interpersonal psychotherapy is designed to improve interpersonal functioning and self-esteem, reduce negative affect and, in turn, decrease ED symptoms
30
# Interpersonal psychotherapy for EDs interpersonal problem areas | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
treatment focuses on the resolution of problems within four social domains that are associated with the onset and/or maintenance of the eating disorder: 1. **interpersonal deficits** - apply to those patients who are either socially isolated or who are involved in chronically unfulfilling relationships 2. **interpersonal role disputes** - refer to conflicts with a significant other that emerge from differences in expectations about the relationship 3. **role transitions** - include difficulties associated with a change in life status 4. **grief** - when the onset of the patient’s symptoms is associated with either the recent or past loss of a person or a relationship
31
# Interpersonal psychotherapy for EDs the initial phase | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
sessions 1-5 - patient’s current ED symptoms are assessed, and a history of these symptoms is obtained - Formal diagnosis - Diagnosis and treatment expectations discussed - Assignment of ‘sick role’ - serves several functions (e.g. granting patient permission to recover) - Therapist explains IPT rationale + conducts an ‘interpersonal inventory → develops specific interpersonal formulation
32
# Interpersonal psychotherapy for EDs the intermediate phase | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
8-10 sessions - constitutes the ‘work’ stage of the treatment Essential task: assist patient in understanding connections between difficulties in interpersonal functioning & the ED behavior & symptoms **Therapeutic strategies** and goals shaped by the primary problem area targeted in the treatment - strategies: - therapeutic stance = warmth, support & empathy - focusing on goals - making connections - redirecting issues related to ED symptoms - general therapeutic techniques
33
# Interpersonal psychotherapy for EDs the termination phase | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
4-5 sessions - clinician should begin to discuss termination explicitly and address any anxiety the patient may be experiencing - Prepare patient for emotions that may arise with termination - Patient encouraged to reflect on progress - Outline goals for after end of treatment - Identify early warning signs of relapse + make POA
34
# Outcome studies and empirical findings IPT for bulimia | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
IPT shown to be effective for the treatment of BN + is the only psychological treatment for BN that has demonstrated long-term outcomes that are comparable to those of CBT Currently, IPT is considered an alternative to CBT for the treatment of BN
35
# Outcome studies and empirical findings IPT for BED | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
For the treatment of BED among adults, IPT has been demonstrated to be effective in randomized controlled studies In 2 randomized trials comparing IPT with CBT, IPT had similar effects to CBT in the treatment and management of BED IPT may be considered a first-line treatment for BED
36
# Outcome studies and empirical findings IPT for anorexia | Burke (2018) ## Footnote Interpersonal Psychotherapy for the Treatment of Eating Disorders
In general, there are very few effective treatments for AN There is a relative lack of research examining IPT’s utility for AN - there have been no controlled studies yet that have demonstrated the efficacy of IPT for AN May be that for AN, IPT is optimally delivered in the context of other adjunctive treatments (e.g., pharmacological, nutritional), rather than as a “stand alone” treatment
37
pharmacotherapy for bulimia | Davis (2017) ## Footnote Pharmacotherapy of eating disorders
Utility of medications in the treatment of BN has been well established **Antidepressant medication** - fluoxetine: most commonly prescribed for treatment of BN - found that 60 mg/day of fluoxetine was superior to placebo and 20 mg/ day in reducing binge-purge frequency **Antiepileptic medications** - topiramate: used to treat epilepsy - associated with effects on weight and appetite - mixed results for BN
38
pharmacotherapy for BED | Davis (2017) ## Footnote Pharmacotherapy of eating disorders
**Antidepressants** - generally been shown to reduce binge eating in BED - but little impact on weight loss **Weight management medication** - differing results for different medications - Some help with weight loss but not binging, others help w binging but have neg side effects, etc **Stimulant medications** - generally have appetite suppressing effects - LDX: first medication to receive indication from FDA for treatment of BED - found to results in sig reductions in binge eating frequency + decreased weight **Chromium** = an essential mineral - has recently been examined for treatment of BED - limited conclusions
39
pharmacotherapy for anorexia | Davis (2017) ## Footnote Pharmacotherapy of eating disorders
Many medications have been considered for the treatment of AN with generally disappointing results = pharmacotherapy is not typically the primary means of treatment for AN **Antidepressants** - have consistently been no better than placebo at achieving changes to weight or any associated psychological symptoms **Antipsychotics** - first-generation antipsychotics did not demonstrate significant clinical benefits - BUT development of second-generation antipsychotics has shown more promise - Olanzapine most notable - associated with a small but significant difference in rate of weight gain
40
pharmacotherapy for EDs - conclusion | Davis (2017) ## Footnote Pharmacotherapy of eating disorders
**Medications are clinically useful in the treatment of BN and BED** - Although they are often utilized in combination with targeted psychotherapy and other behavioral management strategies SSRIs and other antidepressants are particularly useful in BN For BED, medications associated with appetite and weight reduction, such as the stimulant LDX, have demonstrated success AN poses a greater treatment challenge as the medications useful for other eating disorders offer no significant benefit in AN
41
# results outcome of compulsory treatment | Elzakkers (2014) ## Footnote Compulsory Treatment in Anorexia Nervosa: A Review
5 studies - found that patients in the compulsory group have more severe symptoms regarding both the AN as well as more severe comorbidity Weight at discharge was similar for both the voluntarily treated and the compulsorily detained groups No worsening of therapeutic relationship when compulsorily detained + patients remained in treatment voluntarily
42
# results risk factors for compulsory treatment | Elzakkers (2014) ## Footnote Compulsory Treatment in Anorexia Nervosa: A Review
only studied in 1 study - found that the risk factors were: - Prior AN admissions - More comorbidity - Lower BMI **= a higher illness severity or complexity results in a higher likelihood of compulsory treatment**
43
# results patient views on compulsory treatment | Elzakkers (2014) ## Footnote Compulsory Treatment in Anorexia Nervosa: A Review
Study: nearly half of the patients who denied (the need for) treatment at admission converted to acknowledging the need for admittance within 2 weeks of hospitalization - **Adherence to treatment does not seem to be worsened by the use of compulsion** in general psychiatry Study: most interviewed patients reported that compulsory treatment was “self evidently” the right thing to do - Many patients who themselves had experienced compulsory treatment were grateful in hindsight
44
# results discussion | Elzakkers (2014) ## Footnote Compulsory Treatment in Anorexia Nervosa: A Review
Outcome (main conclusion): short term outcome of detained patients is similar to that of patients that are voluntarily treated - Important bc otherwise these patients would not have been treated if not for legal measures (i.e., the fact that compulsory treatment is legal) - Outcome at discharge is similar to those of voluntarily - important bc those compulsorily detained have higher levels of psychopathology Patients views: AN patients’ views on compulsory treatment appear to be similar to those of other psychiatric patients,
45
therapist empathy and validation in treating AN | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
Validation of the client's experience is crucial to engagement/success, however, accurate empathy is unusually difficult to sustain with anorexic clients Principles for sensitizing therapist to the anorexic population: - Appreciate the fully ego syntonic nature of thinness and self-control - Recognize the desperation that drives symptom 'choice’ - Do not attach surplus meaning to resistance - it is professionally irresponsible to be offended when anorexic clients act anorexic - Acknowledge the difficulty of change
46
# therapist set and style the socratic style | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
**socratic style** = the style of using a series of questions to help clients synthesize info and reach conclusions on their own principles derived from the socratic model: - speak the client's language - respect client's individuality - be collaborative: client's thoughts and feelings are viewed as hypotheses that both the therapist and the client work on together to test and evaluate - be honest - be curious - be focused - be systematic: socratic style uses a series of questions to help clients draw conclusions - be patient
47
# core themes in therapy psychoeducational | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
Anorexic/bulimic individuals have a lot of knowledge on dieting → therapists must know more than their clients and the general public to help disentangle truth and falsehood about eating and dieting
48
# core themes in therapy experimental | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
‘objective, fact-finding approach', where clients are 'true collaborators in the search for unknown factors' Personal disconfirmatory evidence as the most powerful way to provoke change Each step is undertaken w/an attitude of 'let's test this out and see what happens' → the results will be evaluated on the basis of the client's experience rather than the therapist's opinions
49
# core themes in therapy functional | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
A focus on functionality is indicated when clients' beliefs are highly valued, culturally shared, or delusional, so that evidence about their validity is unavailable or irrelevant The most explicit application is a review of advantages and disadvantages
50
conclusion | Vitousek (1998) ## Footnote Enhancing Motivation For Change In Treatment-Resistant Eating Disorders
“In our experience, clinicians who practice the principles we have summarized rarely fail to engage the most reluctant eating-disordered individuals in the therapeutic process” The desire to recover in no sense guarantees the successful achievement of that objective - it is simply a beginning step that most other (non-ed) clients accomplish before their first session As recognized within the substance abuse field (to which ED bares many similarities), change is likely to occur in a spiral rather than linear pattern, with frequent oscillations between the tendencies to advance and retreat