Eating Disorders Flashcards

1
Q

General Hx taking

A

Weight and height
- premorbid, current, lowest, target

HPI

  • onset, progression
  • restrictions
  • feeling about eating
  • stressors
  • any binge eating, methods of compensation after
  • concomitant mood

Anorexic symptoms

  • concern abt weight
  • weight loss methods
  • period irregular or stopping

Bulimic symptoms

  • excessive or out of control eating
  • guilt after eating
  • vomiting
  • use of drugs to help control weight

Psychiatric symptoms

  • depression
  • suicide/self harm (RISK)
  • anxiety

Physical symptoms

  • menstrual hx, delay pubertal events
  • syncope
  • palpitations
  • fatigue
  • muscle weakness
  • sensitivity to cold
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2
Q

Physical examination

A

BMI
Skin - lanugo hairs, loss of head hair, Russell’s sign, drying and scaling skin
Dentition - erosion, cavities
CVS - postural hypotension, bradycardia
GI - constipation
MS - muscle wasting, pathological fractures
Others - core temp (hypothermia), dehydration, swollen parotids (frequent vomiting), nutritional status

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3
Q

Investigation

A
CBC - normocytic anaemia
U&E - raised urea due to dehydration; hypoK, hypoNa, hypoMg, hypochloremia alkalosis due to vomiting
LFT - abnormal
Glucose - hypoBG
Lipids - hypercholesterolemia
TFT
Amylase - raised in vomiting 
ECG
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4
Q

Differential diagnosis for LOW

A
Anorexia nervosa
Bulimia nervosa
Medical causes of low weight 
Depression
Obsessive-Compulsive disorder 
Psychotic disorders
Alcohol or substance abuse
Dementia
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5
Q

Approach to weight loss

A

Rule out physical/medical cause
Rule out other psychiatric disorder causing LOW e.g. substance, affective, psychotic, anxiety

+abnormal attitude to body weight, shape and size

–> BMI <17.5 –> anorexia
–> BMI normal
+ no weight loss and binging –> bulimia (purging)/ binge eating disorder (no purging)
+ rapid weight loss –> subclinical AN

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6
Q

Anorexia nervosa 厭食症 - main features and criteria

A

LOW WEIGHT (major difference from bulimia

  • overvalued ideas about body shape and weight
  • preoccupation with being thin; intrusive dread of fatness

Criteria

  1. restriction of energy intake causing significantly low weight (<17.5 kg/m2)
  2. intense fear of gaining weight EVEN THOUGH AT SIGNIFICANTLY LOW WEIGHT
  3. disturbance/ DISTORTED in way in which one’s body shape is experienced, persistent lack of recognition of the seriousness of low body weight
    - –> have evidence, everyone says thin but still don’t agree

Restricting type = no binging or purging in last 3 months (only dieting, exercising, fasting)

Bulimic type (purging or non-purging) = have binging +/- purging (vomiting, laxatives, diuretics)/ non-purging (only intensive exercise) in last 3 months

Weight loss not due to thyrotoxicosis, T1DM, TB, malignancy, hypopituitarism

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7
Q

Aetiology of AN

A

Multifactorial and individual specific

  • personality, coping, self-esteem, family, peer, relationships, stress, media
  • biological - 5HT metabolism implicated
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8
Q

Non-fat phobic attributions

A

Not actively trying to lose weight

Stomach bloating, stomach pain, no hunger, no appetite, fear of food

90% are fat-phobic now

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9
Q

Other features of AN - premorbid, comorbidities

A

Premorbid personality

  • obsessionality –> but egosyntonic and not intrusive (e.g. keeping checking mirror, weighing – feels better after but keeps doing it happily)
  • perfectionism/rigid/arrogant
  • low self esteem

Psychiatric comorbidities

  • anxiety disorders may preceded (GAD, SAD)
  • depression concurrent or after
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10
Q

AN converting to BN vs Bulimic type of AN

A

Bulimic type of AN
- still grossly underweight, amenorrhea

AN convert to BN

  • AN return to normal weight, period return then change to BN
  • approx 50%
  • non-purging bulimic type more likely to change to BN
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11
Q

Management of AN - inpatient vs outpatient, immediate management and Ix, long term Mx

A

Inpatient if:
- RISK – e.g. BMI <13-14

Attend to physical condition if abnormally thin (emaciation) or purging present (electrolyte imbalance)
Assess suicide risk and comorbidities

Ix in hospital: weight, height, BMI, vitals, hydration, ECG, BG, U&E

Long term

  • SSRI (although no medication proven to be effective)
  • Slowly increase calorie intake, negotiate target weight and plan –> target to increase weight 0.5-1kg/wk
  • MOTIVATION ENHANCEMENT THERAPY (when physical condition ok; ineffective when starved) –> externalise problem (patient themselves versus AN), promote self-motivation for change, avoid confrontation, enhance sense of control, understand the function of AN to the patient (explore issues of self-esteem, perfectionism)
  • Patient psychoeducation (balanced eating, complications, nature of eating disorders)
  • FAMILY PSYCHOEDUCATION
  • “Contract” about eating after discharge/ objective consequences –> decrease family conflict and stress
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12
Q

Poor prognostic factors for AN

A
Marked degree of weight loss
Older age of onset
Chronicity 
Presence of binging/purging
Marked fat phobia
Comorbidity
FHx
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13
Q

Refeeding syndrome

A

Risk when eating after >5 days of starvation

HypoPO4, hypoK, hypoNa, hypoMg, metabolic acidosis, thiamine deficiency
–> muscle weakness, seizures, oedema, cardiac dysrhythmias (insulin rise = shift of K and PO4 into cells = hypoK –> DANGEROUS), hypotension, delirium

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14
Q

Bulimia nervosa 暴食症

A

Preoccupation with eating and irresistible craving of food, resulting in BINGE EATING
Sense of lack of control, followed by feelings of shame and disgust
Counteract with purging, fasting or exercising

Criteria:

  1. Recurrent episodes of binge eating characterised by
    - eating an amount of food that is definitely larger than what most individuals would eat
    - sense of LACK OF CONTROL over eating during the episode
  2. Recurrent inappropriate compensatory behaviours to prevent weight gain
    - purging: vomiting, laxatives, diuretics, other medications
    - non-purging: fasting, excessive exercise
  3. AT LEAST ONCE A WEEK FOR 3 MONTHS
  4. Self evaluation is influenced by body shape and weight
  5. Doesn’t occur exclusively during episodes of AN
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15
Q

Binging vs Over-eating - must clarify in Hx!!

A
Strong sense of lack of control
Do in private
Preceded by negative emotional state
Followed by inappropriate compensation
Objectively large amount of food
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16
Q

BN - weight

A

Relatively normal weight - but “feels fat” – always fat phobic

17
Q

Negative cycle of BN

A

Have food restriction after binging –> starvation will further precipitate bulimic episodes

“starving body demanding to be fed” - over control to lack of control

18
Q

Physical signs in BN

A
Russell's sign (not all have)
Swollen parotids
Dental erosion
Oesophagitis
Complications of laxative abuse
19
Q

BN comorbidities

A
MDD
SA
Suicidal attempts
Shoplifting (impulse control)
Bankruptcy
20
Q

Aetiology of BN - genetic, environment

A

Genetic

  • 54-83%
  • 5HT, NA, plasma endorphins implicated
  • FHx of depression or SA

Environmental

  • Hx of childhood obesity, parental obesity
  • family stress
  • perfectionism, personality disorders
  • alcohol and substance abuse
  • depression
21
Q

Management of BN

A

Usually outpatient

COGNITIVE BEHAVIOURAL THERAPY FIRST LINE

  • most evidence based
  • ONCE/WK for 12 WEEKS
Psychoeducation
Encourage 3 meals/day
Self monitoring, stimulus control
Family therapy 
Stress management 

Fluoxetine can be used to improve coping but doesn’t change eating disorder

22
Q

Poor prognostic factors for BN

A

Personality problem (impulsive trait)
Comorbid depression, repeated suicidal attempts
Marked social isolation
Fail to improve with initial psychotherapy