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EAS Flashcards

1
Q

Filaggrin binds ___

A

Keratin

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2
Q

Free ribosomes generally make proteins that will be ___ while the RER ribosomal components make proteins that will be ___

A

imported, exported

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3
Q

Nucleolus location and two main functions

A

Inside Nuc.; rRNA transcription & maturation/assembly of ribosomes.

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4
Q

COPI proteins use KDEL receptors to

A

Package vesicles in the retrieval cis pathway back to ER

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5
Q

At the end of the ___ week the embryo has the flat disc

A

3rd

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6
Q

The ___ stain visualizes the nucleus with a blue dye and a positive charge (so it stains negative structures) For LM

A

Hematoxylin (H)

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7
Q

Somatopleuric Mesoderm

A

gives rise to inner lining of body wall and parts of limbs

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8
Q

Stratified Epithelium

A

MORE than one layer WITHOUT intervening basement membrane

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9
Q

Ribosomes are made in the___

A

Nucleolus

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10
Q

Vesicles that have the ___ Marker will be segregated to the lysosomal pathway

A

Mannose 6 phosphate M6P

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11
Q

The primary endoderm cells (hypoblast) migrate over the inner surface of ___ and differentiate into ___ which secrete an extracellular matrix.

A

Cytotrophoblasts, Extraembryonic Endoderm

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12
Q

The Corpus Luteum secretes ___ until middle of first trimester. Then chorion secretes the ___ (same answer)

A

Progesterone

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13
Q

Two classifications of Secretory portion

A

Tubular or Acinar

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14
Q

Euchromatin stains ___ and is transcriptionally ____

A

Lighter, Active

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15
Q

The trophoblast secretes ___ which feeds back and supports the survival of corpus luteum

A

Humn Chorionic Gonadotropin (hCG)

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16
Q

The Zonula Adherens, or intermediate junctions, are found ___ the Zonula occuldens

A

Below

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17
Q

Gap junctions are composed of ___ proteins and allow cell-cell communication

A

Connexin

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18
Q

The outer surface of the nuclear envelope often contains _____ and is continuous with the ___

A

Ribosomes, RER

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19
Q

COPII proteins

A

Package vesicles in the forward trans direction towards the membrane

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20
Q

Claudin and Occludin are two proteins that compose _____

A

Tight Junctions

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21
Q

Special Antigen presenting cells found in Stratum Spinosum

A

Langerhans’ Cells (Dendritic (star-shaped) cells

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22
Q

Lateral Plate Mesoderm

A

contributes to body wall and digestive tract

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23
Q

The copper-containing enzyme, ___ converts ___ to Melanin

A

Tyrosinase, Tyrosine

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24
Q

Apocrine

A

Top portion of cell release

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25
Q

RU486 is a ____ inhibitor to the hormone ___ to promote menses

A

Competitive, Progesterone

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26
Q

The three layers of the enometrium are:

A
  1. Compact Layer
  2. Spongy Layer
  3. Basal Layer
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27
Q

Partial hydatiform Moles are caused by ___ karyotype

A

Triploid

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28
Q

Merocrine

A

Vesicular release

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29
Q

The Nucleolonema consists of the ___ and the ___ but not the _______

A

Pars Fibrosa and Pars Granulosa, NOT the Pars Amorpha

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30
Q

Glycogen can be identified by its lack of ___

A

Membrane

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31
Q

Myoepithelial cells

A

Facilitate secretions in the secretory portion of sweat glands

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32
Q

Eight Locations for Ectopic Pregnancy

A
  1. Fimbrial
  2. Ampullary
  3. Isthemic
  4. Ovarian
  5. Interstitial
  6. Cervical
  7. Abdominal
  8. Rectouterine Pouch
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33
Q

Where is Keratyoyalin and Lamellar Granules found?

A

Stratum Granulosum

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34
Q

The _____ cells form both the embryonic mesoderm and the extraembryonic mesoderm

A

Epiblast

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35
Q

A___ microscope has a 1-1.45nm Resolution with 500,000x and Up magnification

A

TEM

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36
Q

The ER performs

  1. Cleavage of ____
  2. Facilitates proper ____
  3. Attaches ___ to maturing proteins
  4. SER synthesizes __,__,___
  5. Contains enzymes to ___
A 
Signal Peptides
Protein Folding 
Oligosaccharides
Lipids, Steroids, Fats
Detox drugs
37
Q

The _____ is made up of Type IV collagen, glycoproteins, laminin, entactic and heparin sulfate AND it is where Cells lie

A

Basal Lamina

38
Q

Lower wavelengths correspond with ___ resolution, think electron vs light microscope

39
Q

The ____ Layer of the Dermis contains loose connective tissue, extensive capillary network, and nerve endings that are free and encapsulated as seen in Meissners’ corpuscles

40
Q

Telogen Phase

A

Resting phase; Club hair is final hair product

41
Q

Two classifications of Ducts

A

Simple/Unbranched or Compound/Branched

42
Q

Women with pre-eclampsia have an increase in ___ and a decrease of ___, therefore flooding the mother with (answer 2) alleviates the problem

A

sFLT-1, PLGF, PLGF

43
Q

The ___ uses Heuser’s membrane, Extraembryonic Ret, and ECM cytotrophoblast cells to migrate

A

Extraembryonic Mesoderm

44
Q

The gradual rise of what hormone leads to the LH and FSH surge?

45
Q

The grainy area where maturing ribosomal subunits are found

A

Pars Granulosa (PG)

46
Q

___ Forming outer layer of yolk sac is major site of Hematopoesis

A

Extraembryonic Mesoderm

47
Q

Nuclear lamins, cells of mesenchymal origin, muscle cells, glial cells, keratins are all __________

A

Intermediate filaments

48
Q

Complete Hydatiform Moles’ Chromosomes are completely derived from which parent?

A

The Father

49
Q

The Krebs cycle occurs in the ___ of the mitochondria

50
Q

___ is used to stain and visualize sugar residues like glycogen and glycoproteins For LM

A

Periodic Acid Schiff

51
Q

Hair Anagen phase

A

Growth; proportionate to anagen

52
Q

Intermediate Mesoderm

A

Located lateral to the paraxial mesoderm, Gives rise to the Urinary system and parts of the reproductive system

53
Q

The two portions of a gland

A

Duct and Secretory

54
Q

Hair Catagen phase

A

Regression; Apoptosis of Keratinocytes

55
Q

The four basic tissue types:

A
  • Nervous
  • Epitheilial
  • Muscle
  • Connective
56
Q

Heterochromatin stains____ and is transcriptionally ____

A

Darker, Inactive

57
Q

The Stratum___ is seen only in thick skin

58
Q

Holocrine

A

Entire cell released

59
Q

The basement membrane has the stronger proteins to anchor the cell called ____

60
Q

A ___ microscope has a 2nm Resolution and 100,000x and up Mag

61
Q

A ___ microscope has 0.2uM rseolution and up to 1500x magnification

62
Q

_____ bind to chromatin of non-dividing cells and are found in the inner surface of the nuclear envelope (facing the inside)

A

Lamina Proteins

63
Q

The ___ layer is the deeper area of the dermis contains dense iregular connective tissue, Rich with Arteriovenous AV shunts, Have pacinian corpuscles, and smooth muscle bundles to insert hair follicles

64
Q

Splanchnopleuric Mesoderm

A

gives rise to covering of viscera

65
Q

Basal Lamina and Lamina reticularis make the ___

A

Basement membrane

66
Q

The Hair ___ is dermal connective tissue essential for induction and maintenance of hair follicle which supplies blood and nerves. Development and cycling is depending on these!!

67
Q

___ builds around Heuser’s membrane and provides a space for Extraembryonic mesoderm formation

A

Extraembryonic Reticulum

68
Q

Part of epidermis responsible for nail formation

A

Nail Matrix

69
Q

Simple Ethilium

A

One layer of cells

70
Q

The mis-shapen nucleolar organizer region

A

Pars Amorpha (PA)

71
Q

Transport proteins known as exportins and importins bind to the _____ to regulate movement.

A

Nuclear Pore complex

72
Q

Paraxial Mesoderm

A

gives rise to Somitomeres; precursors to somites which segment the vertebral column

73
Q

The thread-like area that creates rRNA transcripts

A

Pars Fibrosa (PE)

74
Q

____ is a syndrome recognized by shallow implantation

A

Pre-eclampsia

75
Q

Three types of cell shapes

A

Squamous-Flat
Cuboidal-Cube-like
Columnrar-Column-like

76
Q

The Duct portion of sweat glands

A

The Re-absorption of Na, K, Cl opens directly on a sweat pore

77
Q

The Unfertilized egg cells are lock in the ______ of the cell cycle

A

Second Meitoic Metaphase

78
Q

The nuclear envelope has ___ (how many) membranes

79
Q

New proteins have a ___ at its N-terminus which binds to a ___ to temporarily stop elongation and allow the complex to bind to a receptor on the outer surface o the ER. This allows the protein to be translocated through the ER membrane into the ER lumen to be modified.

A

Signal Peptide, Signal Recognition Particle.

80
Q

Out of Prokaryotes, Archaea, and Eukaryotes, which of these have membrane bound organelles?

A

Eukaryotes

81
Q

Prechordal Plate Mesoderm

A

Induces midline structures such as brain;

82
Q

Inermediate junctions are mediated by ___ proteins

83
Q

The two skin layers which have mitotic activity are:

A

Stratum Basale(Germinativum) and Stratum Spinosum

84
Q

The sweat glands’ secretory portion may consist of either ___ cells which contain glycoprotein granules or ___ which have no granules and are essential for ion and water transport.

A

Dark, Clear

85
Q

The ___ stain visualizes the cytoplasm with a pink dye and a negative charge (so it stains positive structures) For LM

86
Q

Aldehyde Fuschin

A

Elastic Fibers

87
Q

Orcein

A

Collagen Fibers

88
Q

Silver

A

Golgi Apparatus, Reticular Fibers

Exam 1 (4 decks)

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