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Exam 1 > EAS > Flashcards

EAS Flashcards

1
Q

Filaggrin binds ___

A

Keratin

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2
Q

Free ribosomes generally make proteins that will be ___ while the RER ribosomal components make proteins that will be ___

A

imported, exported

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3
Q

Nucleolus location and two main functions

A

Inside Nuc.; rRNA transcription & maturation/assembly of ribosomes.

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4
Q

COPI proteins use KDEL receptors to

A

Package vesicles in the retrieval cis pathway back to ER

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5
Q

At the end of the ___ week the embryo has the flat disc

A

3rd

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6
Q

The ___ stain visualizes the nucleus with a blue dye and a positive charge (so it stains negative structures) For LM

A

Hematoxylin (H)

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7
Q

Somatopleuric Mesoderm

A

gives rise to inner lining of body wall and parts of limbs

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8
Q

Stratified Epithelium

A

MORE than one layer WITHOUT intervening basement membrane

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9
Q

Ribosomes are made in the___

A

Nucleolus

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10
Q

Vesicles that have the ___ Marker will be segregated to the lysosomal pathway

A

Mannose 6 phosphate M6P

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11
Q

The primary endoderm cells (hypoblast) migrate over the inner surface of ___ and differentiate into ___ which secrete an extracellular matrix.

A

Cytotrophoblasts, Extraembryonic Endoderm

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12
Q

The Corpus Luteum secretes ___ until middle of first trimester. Then chorion secretes the ___ (same answer)

A

Progesterone

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13
Q

Two classifications of Secretory portion

A

Tubular or Acinar

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14
Q

Euchromatin stains ___ and is transcriptionally ____

A

Lighter, Active

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15
Q

The trophoblast secretes ___ which feeds back and supports the survival of corpus luteum

A

Humn Chorionic Gonadotropin (hCG)

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16
Q

The Zonula Adherens, or intermediate junctions, are found ___ the Zonula occuldens

A

Below

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17
Q

Gap junctions are composed of ___ proteins and allow cell-cell communication

A

Connexin

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18
Q

The outer surface of the nuclear envelope often contains _____ and is continuous with the ___

A

Ribosomes, RER

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19
Q

COPII proteins

A

Package vesicles in the forward trans direction towards the membrane

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20
Q

Claudin and Occludin are two proteins that compose _____

A

Tight Junctions

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21
Q

Special Antigen presenting cells found in Stratum Spinosum

A

Langerhans’ Cells (Dendritic (star-shaped) cells

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22
Q

Lateral Plate Mesoderm

A

contributes to body wall and digestive tract

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23
Q

The copper-containing enzyme, ___ converts ___ to Melanin

A

Tyrosinase, Tyrosine

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24
Q

Apocrine

A

Top portion of cell release

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25
Q

RU486 is a ____ inhibitor to the hormone ___ to promote menses

A

Competitive, Progesterone

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26
Q

The three layers of the enometrium are:

A
  1. Compact Layer
  2. Spongy Layer
  3. Basal Layer
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27
Q

Partial hydatiform Moles are caused by ___ karyotype

A

Triploid

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28
Q

Merocrine

A

Vesicular release

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29
Q

The Nucleolonema consists of the ___ and the ___ but not the _______

A

Pars Fibrosa and Pars Granulosa, NOT the Pars Amorpha

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30
Q

Glycogen can be identified by its lack of ___

A

Membrane

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31
Q

Myoepithelial cells

A

Facilitate secretions in the secretory portion of sweat glands

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32
Q

Eight Locations for Ectopic Pregnancy

A
  1. Fimbrial
  2. Ampullary
  3. Isthemic
  4. Ovarian
  5. Interstitial
  6. Cervical
  7. Abdominal
  8. Rectouterine Pouch
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33
Q

Where is Keratyoyalin and Lamellar Granules found?

A

Stratum Granulosum

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34
Q

The _____ cells form both the embryonic mesoderm and the extraembryonic mesoderm

A

Epiblast

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35
Q

A___ microscope has a 1-1.45nm Resolution with 500,000x and Up magnification

A

TEM

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36
Q

The ER performs

  1. Cleavage of ____
  2. Facilitates proper ____
  3. Attaches ___ to maturing proteins
  4. SER synthesizes __,__,___
  5. Contains enzymes to ___
A 
Signal Peptides
Protein Folding 
Oligosaccharides
Lipids, Steroids, Fats
Detox drugs
37
Q

The _____ is made up of Type IV collagen, glycoproteins, laminin, entactic and heparin sulfate AND it is where Cells lie

A

Basal Lamina

38
Q

Lower wavelengths correspond with ___ resolution, think electron vs light microscope

A

Better

39
Q

The ____ Layer of the Dermis contains loose connective tissue, extensive capillary network, and nerve endings that are free and encapsulated as seen in Meissners’ corpuscles

A

Papillary

40
Q

Telogen Phase

A

Resting phase; Club hair is final hair product

41
Q

Two classifications of Ducts

A

Simple/Unbranched or Compound/Branched

42
Q

Women with pre-eclampsia have an increase in ___ and a decrease of ___, therefore flooding the mother with (answer 2) alleviates the problem

A

sFLT-1, PLGF, PLGF

43
Q

The ___ uses Heuser’s membrane, Extraembryonic Ret, and ECM cytotrophoblast cells to migrate

A

Extraembryonic Mesoderm

44
Q

The gradual rise of what hormone leads to the LH and FSH surge?

A

Estrogen

45
Q

The grainy area where maturing ribosomal subunits are found

A

Pars Granulosa (PG)

46
Q

___ Forming outer layer of yolk sac is major site of Hematopoesis

A

Extraembryonic Mesoderm

47
Q

Nuclear lamins, cells of mesenchymal origin, muscle cells, glial cells, keratins are all __________

A

Intermediate filaments

48
Q

Complete Hydatiform Moles’ Chromosomes are completely derived from which parent?

A

The Father

49
Q

The Krebs cycle occurs in the ___ of the mitochondria

A

Matrix

50
Q

___ is used to stain and visualize sugar residues like glycogen and glycoproteins For LM

A

Periodic Acid Schiff

51
Q

Hair Anagen phase

A

Growth; proportionate to anagen

52
Q

Intermediate Mesoderm

A

Located lateral to the paraxial mesoderm, Gives rise to the Urinary system and parts of the reproductive system

53
Q

The two portions of a gland

A

Duct and Secretory

54
Q

Hair Catagen phase

A

Regression; Apoptosis of Keratinocytes

55
Q

The four basic tissue types:

A
  • Nervous
  • Epitheilial
  • Muscle
  • Connective
56
Q

Heterochromatin stains____ and is transcriptionally ____

A

Darker, Inactive

57
Q

The Stratum___ is seen only in thick skin

A

Lucidum

58
Q

Holocrine

A

Entire cell released

59
Q

The basement membrane has the stronger proteins to anchor the cell called ____

A

Integrins

60
Q

A ___ microscope has a 2nm Resolution and 100,000x and up Mag

A

Scanning

61
Q

A ___ microscope has 0.2uM rseolution and up to 1500x magnification

A

Light

62
Q

_____ bind to chromatin of non-dividing cells and are found in the inner surface of the nuclear envelope (facing the inside)

A

Lamina Proteins

63
Q

The ___ layer is the deeper area of the dermis contains dense iregular connective tissue, Rich with Arteriovenous AV shunts, Have pacinian corpuscles, and smooth muscle bundles to insert hair follicles

A

Reticular

64
Q

Splanchnopleuric Mesoderm

A

gives rise to covering of viscera

65
Q

Basal Lamina and Lamina reticularis make the ___

A

Basement membrane

66
Q

The Hair ___ is dermal connective tissue essential for induction and maintenance of hair follicle which supplies blood and nerves. Development and cycling is depending on these!!

A

Papilla

67
Q

___ builds around Heuser’s membrane and provides a space for Extraembryonic mesoderm formation

A

Extraembryonic Reticulum

68
Q

Part of epidermis responsible for nail formation

A

Nail Matrix

69
Q

Simple Ethilium

A

One layer of cells

70
Q

The mis-shapen nucleolar organizer region

A

Pars Amorpha (PA)

71
Q

Transport proteins known as exportins and importins bind to the _____ to regulate movement.

A

Nuclear Pore complex

72
Q

Paraxial Mesoderm

A

gives rise to Somitomeres; precursors to somites which segment the vertebral column

73
Q

The thread-like area that creates rRNA transcripts

A

Pars Fibrosa (PE)

74
Q

____ is a syndrome recognized by shallow implantation

A

Pre-eclampsia

75
Q

Three types of cell shapes

A

Squamous-Flat
Cuboidal-Cube-like
Columnrar-Column-like

76
Q

The Duct portion of sweat glands

A

The Re-absorption of Na, K, Cl opens directly on a sweat pore

77
Q

The Unfertilized egg cells are lock in the ______ of the cell cycle

A

Second Meitoic Metaphase

78
Q

The nuclear envelope has ___ (how many) membranes

A

Two

79
Q

New proteins have a ___ at its N-terminus which binds to a ___ to temporarily stop elongation and allow the complex to bind to a receptor on the outer surface o the ER. This allows the protein to be translocated through the ER membrane into the ER lumen to be modified.

A

Signal Peptide, Signal Recognition Particle.

80
Q

Out of Prokaryotes, Archaea, and Eukaryotes, which of these have membrane bound organelles?

A

Eukaryotes

81
Q

Prechordal Plate Mesoderm

A

Induces midline structures such as brain;

82
Q

Inermediate junctions are mediated by ___ proteins

A

Cadherin

83
Q

The two skin layers which have mitotic activity are:

A

Stratum Basale(Germinativum) and Stratum Spinosum

84
Q

The sweat glands’ secretory portion may consist of either ___ cells which contain glycoprotein granules or ___ which have no granules and are essential for ion and water transport.

A

Dark, Clear

85
Q

The ___ stain visualizes the cytoplasm with a pink dye and a negative charge (so it stains positive structures) For LM

A

Eosin (E)

86
Q

Aldehyde Fuschin

A

Elastic Fibers

87
Q

Orcein

A

Collagen Fibers

88
Q

Silver

A

Golgi Apparatus, Reticular Fibers

Exam 1 (4 decks)

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