Early Recognition of Stroke Flashcards

1
Q

stroke in the US

A
  • 600,000 new or recurrent strokes each year
  • 158,448 deaths in 1998- 1 of every 14.8 deaths
  • fourth leading cause of death
  • leading cause of disability
  • 4.5 mil stroke survivors alive today
  • 83% ischemic, 17% hemorrhagic
  • effective prevention therapy available
  • emphasis must be on prevention
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2
Q

risk factors for stroke

A

non-modifiable:
-age, sex, race, family history
modifiable:
-HTN, diabetes, smoking, hyperlipidemia, carotid stenosis, a fib

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3
Q

symptoms of stroke

A
  • sudden numbness or weakness of face, arm, or leg, esp on one side of the body
  • sudden confusion or trouble speaking or understanding speech
  • sudden trouble seeing in one or both eyes
  • sudden trouble walking, dizziness, or loss of balance or coordination
  • sudden severe headache with no known cause
  • treatment can be more effective if given quickly
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4
Q

stroke subtypes

A
  • ischemic-small vessel thrombosis 20%, large 30%, embolic stroke 33%
  • hemorrhagic stroke- intracerebral 10%, subarachnoid 7%
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5
Q

stroke mimics

A
  • hypoglycemia
  • mass lesions
  • seizures and postictal states
  • migraine
  • psychogenic hemiparesis
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6
Q

mca left

A

-arm, face, eye fields

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7
Q

common presentations-Left MCA

A
  • right hemiparesis: face=hand >arm >leg
  • aphasia (often mistaken as confusion)
  • expressive- difficulty producing language or no language output
  • receptive-poor comprehension and/or incomprehensible speech
  • ant division- left head and eye deviation (if lesion is on left of frontal eye fields, right will be unopposed so patient will look toward left)
  • posterior division- visual field deficit, aphasia
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8
Q

right MCA common presentation

A
  • left hemiparesis: face=hand>arm>leg
  • neglect: doesn’t acknowledge left visual space or denies their own body parts
  • anterior division-right head and eye deviation
  • posterior division- visual field deficit, neglect
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9
Q

post cerebral artery common presentations

A
  • visual field deficit or cortical blindness if bilateral

- may have hemihypaesthesia-complete loss of sensation of the contralateral face, arm, trunk, and leg

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10
Q

basilar artery common presentations

A
  • altered consciousness or coma
  • often bilateral sign
  • cranial nerve signs and crossed signs
  • right face and left arm/leg
  • loss of pin sensation on left face and right arm/leg
  • oculomotor palsy, nysagmus, palate or tongue weakness
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11
Q

lacunar syndromes

A
  • pure motor hemiplegia: internal capsule face=arm=leg
  • pure sensory hypaesthesia: thalamus face=arm=leg
  • dysarthria clumsy hand syndrome: pons
  • ataxic hemiparesis
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12
Q

clinical pearls

A
  • aphasia usually corresponds to left hemispheric stroke
  • neglect usually indicates right hemispheric stroke
  • patients usually look toward the lesion (frontal eye fields)
  • crossed signs indicate brainstem involvement
  • vertigo of central origin almost always is associated with other cranial nerve deficits
  • vertical nystagmus is brainstem ischemia until proven otherwise
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13
Q

early CT changes of stroke

A
  • early infarct signs
  • hypodensity of grey or white batter
  • obliteration of cortical sulci
  • obscured basal ganglia
  • loss of insular ribbon
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14
Q

hyperdense MCA

A

-more likely to hemorrhage with TPA because so much clot

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15
Q

inclusion for thombolytic therapy

A
  • acute ischemic stroke- not mimic
  • age < 80
  • onset <24
  • absence of exclusionary criteria
  • informed consent
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16
Q

exclusion for theombolytic therapy

A
  • CT signs of hemorrhage or very large infarction
  • undetermined time of onset
  • uncontrollable hypertension or blood sugar
  • recent trauma, major surgery, or bleeding
  • abnormal coag profile
  • rapidly resolving deficit
  • hemodynamic compromise of MI
17
Q

thrombolytic therapy

A
  • treatment group had 30% more patients rated as good outcome at 3 months
  • risks-intracerebral hemorrhage placebo 1% vs trt 6%, 50% of which were fatal
  • other bleeding
18
Q

primary and secondary prevention

A
  • control of modifiable risk factors- HTN, DM, CAD, obesity
  • antihypertensive, cholesterol lowering meds
  • antiplatelet mets
  • anticoag
  • carotid endarerectomy