Early Development Flashcards
dorsal mesoderm derivatives
bone, cartilage, muscle
ventral mesoderm derivatives
kidney, blood
Deletion/LOF mutation of nodal inhibits formation of what entire germ layer?
mesoderm layer; endoderm also affected.
What larger family of proteins does nodal belong to?
TGF beta
Where is the amniotic cavity?
Within the epiplast layer
Where is the yolk sac formed?
Within the hypoblast layer
What structure gives rise to the epilpast and hypoblast layers?
The embryoblast of the blastocyst
What structure gives rise to the fetal part of the placenta?
The trophoblast layer of the blastocyst
What is the area of active invagination called for the early embryo?
Node
teratomas happen when :
The primitive streak does not completely regress.
What tissue types are in teratomas?
Any type of tissue that can make a human (from ectoderm, meso, endo) because these are leftover epiblast cells, which are pluripotent.
spatial co-linearity
In hox expression, the hox genes more