Collagen

Question 1

Three fibril-forming collagen types

Answer 1

I - bone
II - cartilage (joints)
III - skin, blood vessels, internal organs

Question 2

Two fibril associated collagens

Answer 2

IX (9), associate with TII fibrils

XII (12), associate with T1 fibrils

Question 3

Two Network-forming collagens

Answer 3

IV (4), sheetlike network of basal lamina (lamina densa)

VII (7), anchoring fibrils, beneath stratified squamous epithelia

Question 4

Transmembrane type

Answer 4

XVII (17), found in hemidesmosomes

Question 5

Type of disease associated with osteogenesis imperfecta?

Answer 5

T1

Question 6

Type of disease associated with chondrodysplasia?

Answer 6

T2

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Question 7

Type of disease associated with Ehler-Danlos syndrome

Answer 7

T3

Question 8

Type of disease associated with epidermolysis?

Answer 8

TVII (7), anchoring fibrils

Question 9

Reticular cells secrete what type of collagen?

Answer 9

Type III, which has a network of branched cells with few bundles.

Question 10

What stain allows one to see TIII collagen?

Answer 10

Silver stain