E8 Acid-Base chemistry & dyspepsia 5

Question 1

In the equilibrium equation what will increase acidity and hence Ka?

Answer 1

if A- is stabilised (conc increases) relative to HA

Question 2

How does bond energies and bond strength affect?

Answer 2

bond strength weakens on descending group in periodic table, therefore proton easier lost. Also as bond dissociation energy decreases acidity increases

Question 3

What does electronegativity control?

Answer 3

how polarised the bond is

the stability of the conjugate base anion

Question 4

How does electronegativity affect pH?

Answer 4

electronegativity increases across a row in the periodic table therefore increasing acidity

Question 5

Does the electron withdrawing inductive effect or electron donating inductive effect destabilise the anion in the conjugate base?

Answer 5

electron withdrawing - stabilise anion

electron donating - destabilise anion

Question 6

What bonds does the inductive effect use?

Answer 6

sigma

Question 7

What bonds does the mesomeric effect use?

Answer 7

pi

Question 8

If there are more resonance structures is it stable or unstable?

Answer 8

stable

Question 9

Does the electron withdrawing inductive effect or electron donating inductive effect stabilise the cation of the conjugate acid?

Answer 9

electron donating- stabilise cation

electron withdrawing- destabilise cation