Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

COM - MSK II > E2 - CT Dz > Flashcards

E2 - CT Dz Flashcards

1
Q

Large vessel; <40, Asian; Chronic; Long smooth tapered stenosis, “Pulseless” UE; Pulmonary, Retinal (copper-wiring), Renal A., Aorta sxs; Granulomatous w/ giant cells

A

Takayasu Arteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Palpable Purpura; no thrombocytopenia ; IgA deposits

A

Henoch-Schonlein Purpura (IgA Vasculitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Silk Road Epi; HLA-B51; Mouth/Genital/GI Ulcers + Uveitis; Pathergy (pustules at needle stick); Neuro sxs

A

Behcet Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Medium Vessels; HBV +; M>W
Skin - Livedo Reticularis, digital gangrene, nodules
Neuro - Foot drop, Vasculitis neuropathy
GI - intestinal angina
Renal, Cardiac - HTN
SPARE lungs
Dx - Fibrinoid necrosis of vessels W/O granuloma

A

Polyarteritis Nodosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Medium Vessel; INFANTS, Asian; Strawberry tongue; coronary involvment (aneurysm or MI); fever, red eyes, LAD, rash, peeling hands and feet
Tx - IVIg + ASA

A

Kawasaki Dz (Mucocutaneous Lymph Node Syndrome)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

C-ANCA (PR3); Nasal tract (Saddle nose); Lung nodule + cavitary lesion; Renal; Granulomatous inflammation, Necrotizing Vasculitis, Glomerulonephritis

A

Wegener’s Granulomatosis (Granulomatosis w/ Polyangiitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

P-ANCA (MPO); Granulomas + Eosinophilia; Asthma; Palpable purpura

A

Churg-Strauss Syndrome (Eosinophilic Granulomatosis w/ Polyangiitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Young Male Smokers; Medium Vessel (Distal first); Thrombosis (loss of digits); Corkscrew Angiography

A

Thromboangiitis Obliterans (Buerger Dz)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Primary vs. Secondary Raynauds

A 
Primary = 15-30; d/t cold or emotion; B/L; NO ischemia 
Secondary = >30; d/t CTD, Rx, other disorder, U/L; Ischemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HLA-DR4; Large vessels (Cranial AA. + Aortic Arch); HA, jaw claudication, visual change, incr. ESR; >50yo; Giant Cells on Bx
Assoc: Polymyalgia Rheumatica (proximal, symmetrical stiff/sore/pain in shoulder, neck, pelvic girdles, NO inflamm or muscle enzyme abnormalities)

A

Giant Cell Arteritis (Temporal Arteritis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Homogenous ANA+

A

Drug-induced SLE (Anti-Histone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Speckled ANA+

A

Sjogrens (Anti-Ro/La)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Centromere ANA+

A

Limited Sclerosis (CREST)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Nucleolar ANA+

A

Diffuse Sclerosis (Scl70/Topo/RNA Pol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Type III Hypersensitivity (Ag-Ab Complex deposition)

A

SLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

ANA/Anti-ds DNA/Anti-Sm; decr. C3, C4

A

SLE

17
Q

RPR syphilis/Lupus Anticoagulant/Anti-Cardiolipin (Beta2GPI)

A

AP-Ab Syndrome (APS)

18
Q

Cotton Wool Spots

A

SLE/APS

19
Q

ANA/Anti-Histone Ab

A

Rx-induced SLE

20
Q

Anti-Ro (SSA)/Anti-La (SSB)

A

Neonatal Lupus or Sjogrens

21
Q

Permanent Complete Heart block + transient Rashes, Thrombocytopenia, Anemia, Arthritis

A

Neonatal Lupus

22
Q

SLE Tx

A

Avoid sun, NSAIDs, Steroids, Hydroxychloroquine

23
Q

Libman-Sacks Endocarditis (Non-Infectious)

A

Assoc. w/ SLE

24
Q

30-60yo; Thickened/Hardened/Hyperpigmented skin, Fibrosis of skin and organs, Proximal extremities and trunk; Interstitial Lung Dz (Pulm. Function Test to Dx), Carpal Tunnel, LATE Raynauds; decr. sweating, Renal Crisis (HTN, Hemolytic Anemia); Hypothyroid (thyroid fibrosis)

A

Diffuse Sclerosis (dcSSc)

25
Q

Distal Extremities; Raynauds 1st; Pulmonary HTN (Rt. Heart Cath to Dx); CREST (Calcinosis, Raynauds, Esophageal Dysmotility-GERD, Scelrodactyly, Telengiactasias), NO renal crisis; periungal erythema

A

Limited Sclerosis (lcSSc)

26
Q

Skin Patch Morphea W/O Raynauds or Systemic manifestations

A

Localized Sclerosis

27
Q

Anti-Scl70 (Topoisomerase I)/RNA Pol III

A

Diffuse Sclerosis

28
Q

Anti-Centromere

A

Limited Sclerosis

29
Q

GI Malnutrition, Barrett Esophagus (incr. cancer), GAVE (gastric antral vascular ectasia), Primary Biliary Cirrhosis (anti-mitochondrial Ab), Pseudo-obstruction, Malnutrition, small mouth,

A

Diffuse Sclerosis (GI manifestation)

30
Q

Most common cause of death in Scleroderma?

A

Pulmonary

31
Q

Anti-Ro (SSA)/Anti-La (SSB)/+RF/decr. C4/Incr. ESR/incr. IgG

A

Sjogrens Syndrome

32
Q

Associated Risk in Sjogrens

A

B Cell NHL

33
Q

Anti-Jo1/Mi2/MDA5/PI55/PI40 + incr. CK/Aldolase

A

Dermatomyositis

34
Q

BIMODAL age; Helitrope Rash, Shawl Sign, Gottrons Papules, Periungal Erythema

A

Dermatomyositis

35
Q

Associated w/ Dermatomyositis?

A

Malignancy (Ovaria - check TVUS)

36
Q

30-50yo (non-BIMODAL); NO skin changes; Endomysial

A

Polymyositis

37
Q

Anti-Jo1 + Incr. CK + subacute weakness

A

Polymyositis

38
Q

Older Males; weak finger flexion or quads; Endomysial inflamm, Rimmed Vacuoles

A

Inclusion Body Myositis (IBM)

39
Q

Anti-cN1A + elevated or normal CK

A

Inclusion Body Myositis

COM - MSK II (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions