E1: Receptor Location Chart Flashcards
Iris radial (dilator)
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: eye
Cholinergic receptor: None
Adrenergic receptor: alpha1 - contraction causes mydriasis
Iris circular (sphincter)
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Eye
Cholinergic receptor: M3, M2 - contraction causing miosis
Adrenergic receptor: None
Ciliary muscle
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Eye
Cholinergic receptor: M3, M2 - contraction causing miosis
Adrenergic receptor: beta2 - relaxation for far vision
Atria, ventricles (contractibility)
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Heart
Cholinergic receptor: M2 - decrease contractility
Adrenergic receptor: beta 1 > beta2 - increase contractibility
SA and AV nodes
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Heart
Cholinergic receptor: M2, decrease rate of electrical impulses
Adrenergic receptor: beta 1 > beta 2, increase rate of electrical impulses
Arteries and much less veins
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: blood vessels
Cholinergic receptor: M3, decrease constriction (artiodilation); releases EDRF (NO)
Adrenergic receptor: alpha 1 (+++) = constriction
alpha 2, beta2 (+) = dilation
bronchial smooth muscle
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: lung
Cholinergic receptor: M3, bronchoconstriction
Adrenergic receptor: beta 2, bronchodilation
Stomach and motility tone
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: GI tract
Cholinergic receptor: M3, M2; increase
Adrenergic receptor: alpha1/2, beta1/2; decrease
GI Tract sphincters
Cholinergic receptor:
Adrenergic receptor:
Cholinergic receptor: M3, M2; relaxation
Adrenergic receptor: alpha 1; contraction
GI Tract secretions
Cholinergic receptor:
Adrenergic receptor:
Cholinergic receptor: M3, M2; increase
Adrenergic receptor: alpha 2; decrease
Kidney
Tissue:
Cholinergic receptor:
Adrenergic receptor:
Tissue: Renin release
Cholinergic receptor: NONE
Adrenergic receptor: beta1, increase
Detrusor (bladder wall SM)
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Genitourinary
Cholinergic receptor: M3 > M2, contraction
Adrenergic receptor: beta3 > beta2, relaxation
Trigone and sphincter
Effector organ:
Cholinergic receptor:
Adrenergic receptor:
Effector organ: Genitourinary
Cholinergic receptor: M3 > M2, relaxation
Adrenergic receptor: alpha1, contraction
Adrenal medulla
Cholinergic receptor:
Adrenergic receptor:
Cholinergic receptor: nicotinic
Adrenergic receptor: secretion of Epi and NE