E1 Flashcards
What is pulse oximetry dependent on to obtain a measurement?
Pulsatile expansion
Automatic BP standards and important considerations
Average difference +/- 5 mmHg
In reality
• Large variances
• Underestimate MAP during HTN
• Overestimate MAP during HoTN
• Ankle, thigh, calf cuffs never validated
Averaging/trending for measurements reliability
What information is provided by EtCO2
PRIMARY= ventilation
- Pulmonary blood flow
- Aerobic metabolism
- Placement of endotracheal tube/LMA
- Integrity of breathing circuit
- Adequacy of cardiac output
- Dead space (VD) to tidal volume (VT)
Causes, solutions, and description of overdampened system
•↓ SBP=underestimated •↑DBP=over estimated • No dicrotic notch •↓ pulse pressure •Loss of detail d/t • System too rigid • System too short Fix= extension • Problem w/ Fluids/pressure bag Not enough pressure on bag Bag is empty Fix=change bag; ↑ pressure • Air bubbles Fix=remove bubbles from system
What is the law of absorption
Beer-Lambert equation
• If a known intensity of light illuminates a chamber of known dimensions
• then the concentration of a dissolved substance can be determined
Mechanism of metabolic alkalosis
increase PCO2
What are causes of respiratory alkalosis
Increased minute ventilation Over ventilation Abnormal CNS ventilation pulmonary insult (PE) Liver failure sepsis pregnancy
Abnormal renal [hco3] reabsorption and [h] elimination is…
Metabolic acidosis or alkalosis
Characteristics of Oxyhgb dissociation curve in lungs vs tissues/capillaries
O2 uptake in lungs
• Bloody nearly saturated
• Across large range of tensions (LEFT shift)
During passage through systemic capillaries
• Large amount of O2 released (RIGHT shift)
• Relatively small drop in tension
As long as blood is saturated
What is the diagnostic accuracy of invasive BP monitoring?
About 80% accurate
• For color change at 5 second
Pulse oximetry, Doppler doesn’t improve
Describe waveforms of art-line
1: systolic upstroke • Pulsatile flow down artery 2: systolic peak pressure • As ventricle repolarizes 3: systolic decline • Begin diastole 4: dicrotic notch • Produced by blood pushing back on aortic valve • Diastole 5: diastolic runoff • Atrial contraction 6: end-diastolic pressure • DBP
Causes of increased PetCO2 d/t decreased alveolar ventilation
Hypoventilation Resp center depression NM disease High spinal anesthesia COPD
Drawback to sidestream EtCO2 measurement
analyzers have a delay time and rise time
the concept being similar to other expired gas analysis
What determines pH in ECF?
A-B balance between [HCO3] and [CO2]
What physiologic action alters CO2?
Why is this important?
- lung ventilation
- Can help correct respiratory disorders quickly
AANA monitoring standards
Oxygenation
Ventilation
CV
Oxygenation Clinical observation Pulse oximetry ABG’s as indicated Ventilation Auscultation Chest excursion ETCO2 Pressure monitors as indicated Cardiovascular ECG Auscultation as needed BP and HR q 5minutes
Disadvantages of automatic BP. Rationales
Unsuitable in rapidly changing situations Patient discomfort Clinical limitations • Extremes of heart rate, pressure Can cause trauma d/t frequent recycling • Coagulopathies • Peripheral neuropathies • Arterial/venous insufficiency • Compartment syndrome
What is the degree of weak acid dissociation determined by?
What are examples of weak acids?
pH
Temperature
Examples:
albumin, phosphate
What are symptoms of respiratory acidosis
vasodilation
narcosis
cyanosis
Arterial line complications
Distal ischemia or pseudoaneurysm Hemorrhage, hematoma Arterial embolization Local infection Peripheral neuropathy • Nerves and vessels in close proximity
What is the Stewart approach to A-B balance interpretation?
Understanding how strong ion difference (SID), weak acid concentration [Atot] and PaCO2 affect AND explain A-B balance
What is SaO2
A ratio of reduced (deoxygenated) Hb to all Hb
What are limitations and their causes to auscultating BP
↓ peripheral flow • Shock • Intense vasoconstriction Changes in vessel compliance • Severe edema • Calcific arteriosclerosis Shivering incorrect cuff size
What is systolic pressure variation represent and why does it occur
SV changes btwn LH and RH
D/T increased intrathoracic pressure and lung volumes
INC LH and DEC RH SBP d/t end-exp pressure
What happens when lung volume increases from increased intrathoracic pressure to left ventricular preload, afterload, SV
INC LV preload
DEC LV afterload
INC LV SV
Invasive BP monitoring sites
Radial Brachial Posterior tibial Axillary Dorsalis pedis Femoral
Describe the stepwise approach of the traditional A-B analysis. 7 steps
- Is patient hypoxic?
- Is the pH normal?
- Is it respiratory or metabolic? and What are PaCO2 and HCO3 levels?
- Simple or mixed?
- Compensated, partially or uncompensated?
- Suspected or actual cause?
- Treatment?
How is systolic pressure variation measured? Effects of mechanical ventilation
Min pressure, compared to Max pressure
In mechanically ventilated patients
• Normal = 7-10mmHg total
Treatment of respiratory acidosis
Increase Vm
Ventilator setting changes = increase RR or Vt
Treat cause
How are arterial waveforms made?
Summation of sine waves
Fundamental wave + harmonic wave = typical pressure wave
•Fundamental wave = Expansion & contraction of vessel in response to pressure wave
• Systolic
•Harmonic wave = “echo” or “ripple” effect of wave
• Diastolic
What happens when lung volume increases from increased intrathoracic pressure to right ventricular preload, afterload, SV
DEC RH preload/VR
INC RH afterload
DEC RH SV
Distal pulse difference in waveforms in periphery
As pressure wave moves TO periphery: • Arterial upstroke steeper • Systolic peak higher • Dicrotic notch later • Seen later in waveform Longer distance for sine wave to travel • End-diastolic pressure lower • Wider pulse pressure
What are the 3 major causes of decreased PetCO2
Equipment malfunction
Decreased CO2 production and delivery to lungs
Increased alveolar ventilation
Acidic or alkalotic?
[H+] > [OH-]
[OH-]>[H+]
[H+] > [OH-] = acidic
[OH-]>[H+] = alkalotic
What is the bohr equation
(Vd/Vt) = [(PACO2 - PeCO2)/PACO2)
What happens to dissociation curve if blood poorly saturated
• Small amounts of O2 released
• LARGER drop in tension
Steep slope of dissociation curve
What is the treatment for respiratory alkalosis?
Decrease minute ventilation
Make ventilator changes (dec RR or Vt)
Treat cause
What are 3 rules of A-B balance
- Electrical neutrality
- Dissociation equilibriums
- Mass conservation
4 types of adult hb
- Oxyhemoglobin (HbO2)
- Reduced Hb (deoxy)
- Methemoglobin (metHb)
- Carboxyhemoglobin (COHb)
Pulse pressure variation equation
PPV=[(PPmax-PPmin)/(PPmax + PPmin)/2] x100
EtCO2 monitor requirements
CO2 reading within +/- 12% of actual value
Manufacturers must disclose interference caused by ethanol, acetone, halogenated volatiles
Must have a high CO2 alarm for inhaled and exhaled CO2
Must have an alarm for low exhaled CO2
What are Korotkoff phases?
Phase 1 • the most turbulent/audible (SBP) Phase II-III • sound character changes Phase IV-V • muffled/absent (DBP)
How does HbCO compare to HbO2 at 660 and 940? How does HbCO affect SpO2, especially in smokers?
Absorbs as much light in the 660 nm range as oxyhemoglobin does
Falsely elevates SpO2
Each 1% ↑ COHb will ↑ SpO2 1%
Many smokers have >6% COHb
What is SVV
Computer analysis of arterial pulse pressure waveform
Area under the waveform
Correlates resistance and compliance
based on age, gender
computes SV
Describe the Allen’s test
Compresses radial and ulnar arteries Patient makes a tight fist • Exsanguinating the palm Patient opens hand Release ulnar artery • Color of palm should return in < 10 seconds
SV pressure curve and contractility
slope directly r/t contractility
High slope = high contractility
INC stretch = INC contractility = INC CO/SV
Low slope = low contractility
Less stretch = low contractility = dec CO/SV
d/t dec preload
What occurs to substances with polar bonds in water
They dissolve or dissociate into component parts
Degree of H2O dissociation and [H+] is affected by what 3 things
Strong ions
Weak Acids
CO2
How is light absorption affected by solute concentration?
Light absorption must be measured at wavelengths equal to the number of solutes
• More solutes = more light absorbed
• Less solutes absorbs less light