E-test Flashcards

1
Q

The difference between a nucleoside and a nucleotide is that

A. they contain different sugars

B. the bases are attached to the sugars at different carbons

C. one contains phosphate attached via an ester linkage

D. one is used to synthesize DNA and the other, RNA

A

C

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2
Q

The feature(s) of DNA deduced by Watson and Crick included:

A. two antiparallel polynucleotide chains coiled in a helix around a common axis

B. the pyrimidine and purine bases lie on the inside of the helix

C. the bases are nearly perpendicular to the axis

D. all of the answers are correct

A

D

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3
Q

Features of the genetic code include:

A. the code overlaps

B. the code is degenerate

C. a codon is defined by three bases and the code is degenerate

D. a codon is defined by three bases and the code overlaps

A

C

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4
Q

Which of the following is a short section of RNA that is extended by DNA polymerase?

A. telomere

B. primer

C. Okazaki fragment

D. Holliday fragment

A

B

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5
Q

What must happen to the strands of DNA in order for replication to occur?

A. supercoiling

B. annealing

C. melting

D. unwinding

A

D

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6
Q

What was the first free-living organism to have its genome sequenced?

A. Escherichia coli

B. Drosophila melanogaster

C. Haemophilus influenzae

D. Rattus norvegicus

A

C

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7
Q

A plasmid is an example of a common ______.

A. cosmid

B. vector

C. gene

D. chromosome

A

B

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8
Q

What proteins use ATP to separate DNA strands at specific sites?

A. topoisomerases

B. histones

C. gyrases

D. helicases

A

D

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9
Q

Which of the following best describes the directionality of DNA replication?

A. 5’ → 3’ direction on both strands

B. 3’ → 5’ direction on both strands

C. 5’ → 3’ direction on the leading strand, 3’ → 5’ on the lagging strand

D. 3’ → 5’ direction on the leading strand, 5’ → 3’ on the lagging strand

A

A

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10
Q

A pattern of DNA fragments can serve as a _____ of a particular DNA molecule.

A. template

B. primer

C. fingerprint

D. vector

A

C

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11
Q

What name is given to sequences that are found on the same molecule of DNA and contain information such as promoter sites?

A. cis-acting sequences

B. trans-acting sequences

C. syn-acting sequences

D. anti-acting sequences

A

A

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12
Q

What is a complex community of prokaryotes?

A. quorum

B. biofilm

C. leader colony

D. eruption

A

B

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13
Q

Which of the following is required for DNA synthesis but not for RNA synthesis?

A. nucleotide triphosphates

B. DNA sequence that serves as a template

C. promoter

D. primer

A

D

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14
Q

Which of the following is the strongest inducer of the lac operon in cells?

A. allolactose

B. galactose

C. lactose

D. glucose

A

A

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15
Q

Which of the following changes the nucleotide sequence of RNA after transcription occurs, by processes other than RNA splicing?

A. RNA substitution

B. RNA proofing (sker under transkriptionen)

C. RNA editing

D. RNA mutation (sker oftets i splicing)

A

C

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16
Q

Which of the following is most often found in proteins?

A. D-amino acids

B. L-amino acids

C. an equal amount of D- and L-amino acids

D. D- and L-amino acids in 1:4 ratios

A

B

17
Q

Which of the following is often the first step in protein purification from a homogenate?

A. gel electrophoresis

B. centrifugation

C. ion exchange chromatography

D. HPLC

A

B

18
Q

Which of the following amino acids has an ionizable R-group with a pKa near neutral pH?

A. tyrosine

B. serine

C. histidine

D. lysine

A

C

19
Q

Which of the following are used to sequence entire proteins?

A. affinity peptides

B. overlapping peptides

C. circular peptides

D. labelled peptides

A

B

20
Q

The overall three-dimensional structure of a single polypeptide is referred to as _____.

A. primary structure

B. secondary structure selvom der ellers star det i hendes slide….

C. tertiary structure (se kap 2 2.4)

D. quaternary structure

A

C

21
Q

What term describes the RNA-directed process of protein synthesis?

A. transcription

B. translation

C. Merrifield synthesis

D. ribozyme-directed protein synthesis

A

B

22
Q

Allosteric proteins….

A. usually display hyperbolic Michaelis-Menten kinetics.

B. often display cooperativity.

C. always consist of several identical subunits.

D. usually display hyperbolic Michaelis-Menten kinetics and often display cooperativity

A

B

23
Q

What hypothesis explains why some tRNA molecules can bind to more than one codon?

A. jiggle hypothesis

B. wobble hypothesis

C. teeter hypothesis

D. totter hypothesis

A

B

24
Q

Which of the following is the primary proteolytic enzyme of the stomach?

A. trypsin

B. chymotrypsin

C. pepsin

D. elastas

A

C

25
Q

What proteins recognize UAA, UAG, and UGA codons?

A. initiation factors

B. elongation factors

C. release factors

D. termination factors

A

C

26
Q

Another name for an antigenic determinant is _____.

A. epimer

B. epinephrine

C. epitope

D. epimode

A

C

27
Q

An ELISA can be used for

A. quantitative analysis

B. protein sequencing

C. size analysis

D. all of the answers are correct

A

A

28
Q

Which antibody can cause allergic reactions?

A. IgA

B. IgD

C. IgE

D. IgG

A

C

29
Q

What term describes the increase in antibody diversity due to somatic mutation?

A. affinity maturation

B. epitope mutation

C. immunity mutation

D. variable domain maturation

A

A

30
Q

What type of virus is HIV?

A. retrovirus

B. provirus

C. oncovirus

D. enterovirus

A

A