DYSPNEA Flashcards
Better predictor of outcome in COPD between dyspnea & FEV1
DYSPNEA
Peripheral chemo receptors are
Carotid body
aortic arch
Central chemoreceptors
Medulla @
Mechanoreceptors for airway
@upper airway stretch, irritant & j receptors
Chest wall muscle spindle & tendon organ
stimulation of mechanoreceptors cause symptom of chest tightness & decreased compliance
Metabreceptor for pull. Function
Skeletal muscles
Mechanism of dyspnes
Afferent - Efferent mismatch
Air hunger mechanism
Increased drive
Hypoxemia & Hypercapnia (by chemoreceptors @ periphery )
Acute hypercapnia & acidemia ( by chemorecepton, peripheral ¢ral)
Airway & interstitial inflammation (by pulmonary afferents)
Pulmonary vascular receptors
Symptom associated with chest tighten
Inability to deep breathe
May suggest dynamic hyperinflation of COPD
Onthopnea causes
CHF,
mechanical impairment of the diaphragm associated with
obesity, or asthma triggered by esophageal reflux.
Nocturnal dyspnea mechanism
CHF or
asthma
Acute, intermittent episodes of dyspnea causes
myocardial ischemia,
bronchospasm, or
pulmonary embolism,
chronic persistent dyspnea causes
COPD,
interstitial lung disease, and
chronic thromboembolic disease
Definition & cause of PLATYPNEA
dyspnea in the upright position with relief in the supine position :
Left atrial myxoma or
hepatopulmonary syndrome