Dyspepsia and Hpylori Flashcards

1
Q

What are the two types of dyspepsia?

A
  • Functional – dyspepsia but no underlying cause, normal endoscopy
  • Uninvestigated – symptoms in patients who’ve not had an endoscopy
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2
Q

What are the symptoms of dyspepsia?

A
  • Upper abdominal pain for 4 weeks or more
  • Heartburn
  • Acid reflux
  • Fullness
  • Bloating
  • Nausea & vomiting
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3
Q

What are the causes of dyspepsia?

A
  • GORD
  • Peptic ulcer disease
  • Gi malignancy
  • SE of drugs
  • Lifestyle
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4
Q

What are the red flags for dyspepsia?

A
  • Bleeding
  • Dysphagia
  • Recurrent vomiting
  • Weight loss
  • 55+ unexplained recent onset
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5
Q

What required urgent endoscopic investigation?

A
  • Dysphagia
  • Significant acute Gi bleeding
  • Over 55 years with unexplained weight loss and upper abdominal pain, reflux or dyspepsia
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6
Q

What lifestyle advice can be given for dyspepsia?

A
  • Weight loss
  • Reducing alcohol and smoking cessation
  • Improve diet (sugar, fatty foods, spicy)
  • Raise cushion to avoid acid reflux
  • Stop/avoid medications that cause dyspepsia
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7
Q

What is the treatment for dyspepsia?

A
  • Lifestyle
  • Antacid / alginates
  • PPI for 4 weeks (Leave a 2 week wash out period after PPI use before testing for Hpylori)
  • Offer H2 receptor antagonist if inadequate response to PPI
    If symptoms persist use PPI or h2 antagonist when required
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8
Q

What drugs can cause dyspepsia?

A
  • Alpha blockers & beta blockers
  • Antimuscarinic
  • Aspirin
  • Alendronic acid
  • Bisphosphonates
  • NSAIDS
  • Corticosteroids
  • Nitrates
  • Theophylline
  • CCB
  • TCA’s
  • SSRI’s
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9
Q

What is the test for HPYLORI?

A

UREA 13C, SAT or blood test

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10
Q

When do you not perform the urea test for hpylori?

A
  • Within 4 weeks of antibiotic treatments
  • Within 2 weeks of PPI treatment
  • Retesting should be performed 4 weeks after treatment
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11
Q

What drugs are used to treat Hpylori?

A
  • PPI
  • Clarithromycin
  • Amoxicillin/ metronidazole
  • Tetracycline/levofloxacin
  • Bismuth subsalicylate
  • Rifabutin or furazolidone
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