Dyspepsia

Question 1

What is dyspepsia?

Answer 1

Combination of symptoms indicating an upper GI problem

Question 2

What is typically involved in dyspepsia as an umbrella term?

Answer 2

Epigastric pain/burning
Early satiety and post-prandial fullness
Belching
Bloating
Nausea
Upper abdominal discomfort

Question 3

Differentials of dyspepsia?

Answer 3

PUD
Gastric cancer
GORD
Oesophageal cancer
Biliary/pancreatic pathology
Non-ulcer dyspepsia (diagnosis of exclusion = negative endoscopy)

Question 4

Approach to investigations of dyspepsia?

Answer 4

Age + red flags

<55 + no red flags

• lifestyle changes and drug review
• trial of PPI/triple therapy (breath test/stool antigen)

> 55 +/- red flags

• UGI endoscopy
• Biopsy and histology