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P2 therapeutics > Dyslipidemia Quiz Drug Formulary > Flashcards

Dyslipidemia Quiz Drug Formulary Flashcards

1
Q

Atorvastatin

A

Lipitor

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2
Q

Rosuvastatin

A

Crestor

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3
Q

Simvastatin

A

Zocor

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4
Q

Pravastatin

A

Pravachol

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5
Q

Lovastatin

A

Altoprev, Mevacor

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6
Q

Pitavastatin

A

Livalo

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7
Q

Fluvastatin

A

Lescol

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8
Q

Ezetimibe

A

Zetia

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9
Q

Evolocumab

A

Repatha

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10
Q

Alirocumab

A

Praluent

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11
Q

Cholestyramine

A

Questran

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12
Q

Colsevelem

A

Welchol

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13
Q

Colestipol

A

Colestid

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14
Q

Fenofibrate

A

Tricor

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15
Q

Gemfibrozil

A

Lopid

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16
Q

Omega-3 fatty acid

A

Lovaza

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17
Q

Icosapent ethyl

A

Vascepa

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18
Q

Niacin

A

Niacor

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19
Q

Ezetimibe (Zetia) drug class

A

Cholesterol absorption inhibitor

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20
Q

Evolocumab (Repatha) & Alirocumab (Praluent) drug class

A

PCSK-9 Inhibitors

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21
Q

Cholestyramine (Questran), Colsevelem (Welchol), Colestipol (Colestid) drug class

A

Bile acid sequestrants

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22
Q

Fenofibrate (Tricor) & Gemfibrozil (Lopid) drug class

A

Fibrates

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23
Q

Omega-3 fatty acid (Lovaza) & Icosapent ethyl (Vascepa) drug class

A

Omega-3 fatty acids

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24
Q

Niacin (Niacor) drug class

A

Other (antilipemic agent)

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25
Q

Statin side effects

A

headache, diarrhea, muscle pain, dark urine, sleep problems, dizziness

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26
Q

ezetimibe side effects

A

fatigue, diarrhea, GI upset

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27
Q

PCSK-9 Inhibitor side effects

A

flu like symptoms, muscle pain, injection site soreness,

28
Q

Bile Acid Sequestrant side effects

A

constipation, stomach pain, heartburn, loss of appetite, indigestion

29
Q

fibrate side effects

A

abdominal pain, nausea, back pain, skin rash, jaundice

30
Q

omega-3 fatty acid side effects

A

diarrhea, abdominal pain, nausea, eructation (burping), bad taste (dysgeusia)

31
Q

Niacin side effects

A

flushing, diarrhea, cough, fatigue, abdominal pain

32
Q

statin contraindications

A

pregnancy, lactation, liver failure/cirrhosis

33
Q

cholesterol absorption inhibitors (ezetimibe) contraindications

A

pregnancy, lactation, liver disease, elevated serum transaminase

34
Q

PCSK-9 inhibitor contraindications

A

hypersensitivity, latex (repatha packaging)

35
Q

Bile acid sequestrant contraindications

A

complete biliary obstruction, gastroparesis, at risk for bowel obstruction, renal impairment

36
Q

fibrate contraindications

A

liver disease, biliary cirrhosis, kidney disease, gallbladder disease, pregnancy, breast feeding

37
Q

Omega-3 fatty acid contraindications

A

diabetes, a fib, liver, thyroid, pancreatic disease

38
Q

Niacin (Niacor) contraindications

A

hepatic disease, elevations in hepatic transaminases, active peptic ulcer, arterial hemorrhage, pregnancy and lactation

39
Q

Statin monitoring parameters

A

check lipid panel at baseline, 6-8 weeks after stating, then every 4-6 months. Check LFTs at baseline, after 12 weeks, then annually

40
Q

Ezetimibe monitoring parameters

A

liver function tests

41
Q

PCSK-9 inhibitors monitoring parameters

A

LDL levels

42
Q

Bile acid sequestrant monitoring parameters

A

Triaglycerides

43
Q

Fibrates monitoring parameters

A

none unless concomitant disease (renal, serum transaminases, gallbladder, PT/INR)

44
Q

Omega-3 fatty acid monitoring parameters

A

LDL levels, AST, ALT in patients with hepatic impairment

45
Q

Niacin monitoring parameters

A

blood sugar in diabetes patients, phosphorus levels for pts at risk for hypophosphatemia

46
Q

Low intensity statins

A

simvastatin 10 mg, pravastatin 10-20 mg, lovastatin 20 mg, fluvastatin 20-40 mg

47
Q

Moderate intensity statins

A

atorvastatin 10-20 mg, rosuvastatin 5-10 mg, simvastatin 20-40 mg, pravastatin 40-80 mg, lovastatin 40-80 mg, fluvastatin 40 mg BID, fluvastatin XL 80 mg, pitavastatin 1-4 mg

48
Q

High intensity statins

A

atorvastatin 40-80 mg, rosuvastatin 20-40 mg

49
Q

Atorvastatin dosing

A

Moderate intensity: 10-20 mg
High intensity: 40-80 mg

50
Q

Rosuvastatin dosing

A

moderate intensity: 5-10 mg
high-intensity: 20-40 mg

51
Q

Simvastatin dosing

A

low intensity: 10 mg
moderate intensity: 20-40 mg

52
Q

Pravastatin dosing

A

low intensity: 10-20 mg
moderare intensity: 40-80 mg

53
Q

lovastatin dosing

A

low intensity: 20 mg
moderate intensity: 40-80 mg

54
Q

pitavastatin dosing

A

moderate intensity: 1-4 mg

55
Q

fluvastatin dosing

A

low intensity: 20-40 mg
moderate intensity: 40 mg BID or XL 80 mg

56
Q

ezetimibe dosing

A

10 mg

57
Q

evolocumab dosing

A

140 mg every 2 weeks or 420 mg monthly

58
Q

alirocumab dosing

A

75 mg every 2 weeks or 300 mg monthly

59
Q

cholestyramine dosing

A

4-16 g

60
Q

colsevelam dosing

A

3.75 g

61
Q

colestipol dosing

A

5-30 g

62
Q

fenofibrate dosing

A

40-160 mg

63
Q

gemfibrozil dosing

A

600 mg BID

64
Q

omega-3 fatty acid dosing

A

2 g BID or 4 g QD

65
Q

icosapent ethyl dosing

A

2 g BID

66
Q

niacin dosing

A

initial 200 mg - max 6 g / day (3 doses)

P2 therapeutics (3 decks)

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