Dyslipidemia Formulary Flashcards
brand name: atorvatstatin
Lipitor
dosing: atorvastatin
Moderate: 10-20 mg daily
High: 40-80 mg daily
adverse effects: statins
- muscle symptoms
- fatigue
monitoring: statins
FLP
- baseline
- 4-12 weeks following statin initiation
- every 3-12 months as clinically indicated
Consider also:
- baseline CK in individuals with increased risk of adverse muscle effectss
- CK while on statin therapy in individuals with muscle symptoms
- hepatic function in individuals with s/sxs of hepatotoxicity
brand name: rosuvastatin
Crestor
dosing: rosuvastatin
moderate: 5-10 mg
high: 20-40 mg
brand name: simvastatin
zocor
dosing: simvastatin
low: 10 mg
moderate: 20-40 mg
brand name: pravastin
Pravachol
dosing: pravastatin
low: 10-20 mg
moderate: 40-80 mg
brand name: lovastatin
Altoprev, Mevacor
dosing: lovastatin
low: 20 mg
moderate: 40-80 mg
brand name: pitastatin
Livalo
dosing: pitastatin
Moderate: 1-4 mg
brand name: fluvastatin
Lescol
dosing: fluvastatin
low: 20-40 mg
moderate: fluvastatin 40 mg BID or fluvastatin XL 80 mg
brand name: ezetimibe
Zetia
dosing: ezetimibe
10 mg daily
adverse effects: ezetimibe
- fatigue
- diarrhea
- GI upset
monitoring parameters: ezetimibe
FLP
- 4 to 12 weeks after starting therapy
- rechecked 3 to 12 months therafter
Hepatic Transanimase levels
- baseline FLTs
brand name: evolucumab
Repatha
dosing: evolucumab
- 140 mg once every 12 weeks
- 420 mg once montly
adverse effects: PCSK9 monoclonal antibodies
- GI upset
- increased LFTs
- injection site pain
- myalgia
- influenza
monitoring parameters: PCSK9 monoclonal antibodies
FLP
- Lipid profile (fasting or nonfasting) before initiating treatment
- FLP checked 4-12 weeks after starting therapy
- 3 to 12 months thereafter
- signs and symptoms of allergic reaction
brand name: alirocumab
Praluent
dosing: alirocumab
HFH: 150 mg subq once every 2 weeks
hyperlipidemia: initial 75 mg once every 2 weeks or 300 mg once every 4 weeks. max 150 mg every 2 weeks
brand name: cholestyramine
Questran, Prevalite
dosing: cholestyramine
- initial 4 g 1 to 2 times/day
- maximum 24 g/day
- maintenance: 8 to 16 g/day/2 doses
adverse effects: bile acid resins
- constipation
- bloating
- nausea
- flatulence
- impaired absorption of fat-soluble vitamins (A,D,E,K)
- hypernatremia
- hypercholeremia
- GI obstruction
monitoring parameters: bile acid resins
FLP
- Lipid profile (fasting or nonfasting) before initiating treatment
- FLP checked 4-12 weeks after starting therapy
- 3 to 12 months thereafter
brand name: colsevelam
WelChol
dosing: colesevelam
3.75 g/day in 1 to 2 divided doses
monitoring parameters: colesevelam
HbA1c twice yearly in patients who have stable glycemic control and are meeting treatment goals or quarterly in patients in whom treatment goals have not been met
brand name: colestipol
Colestid
