Dyslipidemia

Question 1

What are lipoproteins?

Answer 1

The protein-lipids complex, they are vehicles for the lipids in the blood

Question 2

What are Apoproteins?

Answer 2

A major component of lipoproteins

Question 3

What is the function of Apoproteins?

Answer 3

Maintaining structural integrity of the lipoproteins, and acting enzymes for lipid metabolism

Question 4

So what do VLDL do?

Answer 4

Carry endogenous TG (triglycerides)

Question 5

What does LDL do?

Answer 5

Delivers cholesterol from the liver to the peripheral tissues

Question 6

What does HDL do?

Answer 6

Removes cholesterol from the peripheral tissues to the liver

Question 7

What do Chylomicrons do and what is their source?

Answer 7

They are formed at the liver, and transport dietary TG

Question 8

What is the biggest lipoprotein?

Answer 8

Chylomicrons

Question 9

Clinical presentation of dyslipidemia

Answer 9

Tendinous Xanthoma, tuberous Xanthoma, even eruptive xanthoma

Question 10

Pharmacotherapy of Dyslipidemia?

Answer 10

Statins to inhibit cholesterol synthesis

Question 11

Commonest side effect of statins?

Answer 11

Myalgia (muscle weakness)

Question 12

What do we give for HyperTG?

Answer 12

Fibrates, they decrease TG production (Fenofibrate)