Dysfunctions of the Adrenal Cortex

Question 1

Affected animals develop a peculiar redistribution of body fat and have potbellied appearance

Answer 1

Hyperadrenocorticism

Question 2

Hyperadrenocorticism

Answer 2

Characterized by hypersecretion of GCCs

Question 3

-Can be primary or secondary

-Seen in cats, rare in horses and other species

Answer 3

Hyperadrenocorticism

Question 4

Accounts for 15% of all cases in dogs and 20% of all cases in cats, caused by adenomas or carcinomas of the adrenal cortex

Answer 4

Primary Hyperadrenocorticism

Question 5

Primary Hyperadrenocorticism:
Atrophy of the corticotropes is seen due to_________

Answer 5

inhibitory effects of GCCs

Question 6

Secondary hyperadrenocorticism:
Accounts for 85% of all cases in dogs caused by

Answer 6

1. Functional tumors
2. Hyperplasia of ACTH-producing cells of the adenohypophysis

Question 7

Secondary hyperadrenocorticism:
In cats (80% of cases), the disease is primarily due to __________

Answer 7

neoplasms of the adenohypophysis

Question 8

Due to prolonged and careless GCC use

Answer 8

Iatrogenic Hyperadrenocorticism

Question 9

Most common form of hypoadrenocorticism, characterized by deficiency in GCC and MCC production due to atrophy or destruction of the zona fasciculata and zone reticularis, or all three cortical zones

Answer 9

Primary hypoadrenocorticism

Question 9

Iatrogenic Hyperadrenocorticism:
Sudden removal of exogenous GCCs causes atrophy of adrenal cortex and corticotropes of the adenohypophysis, eventually leading to _______

Answer 9

hypoadrenocorticism

Question 10

Rare, caused by ACTH hyposecretion causing atrophy of ZF and ZR

Answer 10

Secondary hypoadrenocorticism

Question 11

Follows after iatrogenic hyperadrenocorticism

Answer 11

Iatrogenic hypoadrenocorticism