Dx Reasoning And Differential Diagnosis Flashcards
Diagnosic reasoning
Scientific process in which the practitioner suspects the cause of a patient’s signs and symptoms.
Pertinent positive
The present of a symptom of a sign related to a specific problem
Pertinent negative
The absence of a sign or symptom that if present, suggests a diagnosis
Occam’s razor
Single disease explains multiple symptoms in a patient
Sensitivity
- based on patients with the disease
- is also known as the true positive rate or the proportion of positive test results in individuals with a dx
Specificity
Patients without the dx.
Also known as a true negative rate or the proportion of negative test results in individuals without the dx
Likelihood ratio
Provides unitary measure of the operating characteristics of a sign, symptom, or test expressed as a ratio.
LR= sensitivity/1-specificity
Positive predictive value
Used to predict used to predict the actual probability of a disease for a patient with a positive result.
PV=TP/ all positive = TP\ (TP+FP)
Negative predictive values
Frequency of non disease in persons with negative test results or the probability of not having the dx if the test is negative or if the sign or symptoms is present
A high negative predictive value is consistent with a high specificity value
Prevalence
Refers to the proportion with disease in the population of interest
Equal to the number with disease (TP+FN) divided by the total number in the population.