DX and TX Flashcards

1
Q

Chronic Bronchitis

  • chronic productive cough for at least 3 months a year for 2 consecutive years
  • non-reversible
  • smoking
  • ages 50-60
  • blue bloater: big belly, cyanotic, obese
A

Dx: spirometry
Tx: GOLD Criteria

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2
Q

emphysema

  • loss of elastic recoil and airway collapse
  • smoking
  • AAT deficiency
  • dyspnea, cough
    -pink puffer: barrel chest, skinny
A

Dx: spirometry
Tx: GOLD criteria

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3
Q

bronchiectasis

  • widening and scarring of airways
  • cystic fibrosis
  • thick/dark brown mucopurulent sputum
  • hemoptysis
A

Dx: CT
Tx: mucus clearance

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4
Q

acute bronchitis (viral and bacteria)

  • cough preceded by URI that moves to lower respiratory tract infection
  • at least 5 days
  • winter/fall
A

Dx:clinical
Tx:
viral: supportive, OTC cough med
bacterial: azithro

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5
Q

acute bronchiolitis

  • infection and inflammation of the small airways: bronchioles
  • starts from viral URI
  • RSV
  • infants 2 months to 2 years
  • winter/fall
A

Dx: clinical
Tx: supportive

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6
Q

acute epiglottitis

  • inflammation and swelling of epiglottis that causes serious rapid infection and airway obstruction
  • GAS
  • dysphagia, drooling, distress
  • tripod position
  • hot potato voice
A

Dx: clinical/laryngoscopy (cherry red)
Tx: airway management, ENT referral, and IV Abx (ceftriaxone)

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7
Q

croup

  • inflammation of larynx, trachea, and subglottilc airway
  • 6 months to 3 years age
  • fall/early winter
  • “seal like barking” cough
  • virus: parainfluenza type 1
  • bacteria: S. aureus
A

Dx: clinical
Tx: glucocorticoids (dexamethasone PO), add nebulized epi if severe

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8
Q

empyema

  • pus in the pleural space cavity between lung and chest wall
  • from PNA, lung abscess, Tb
  • chest pain, fever, cough, night sweats
A

Dx: CXR, CT, pleural fluid analysis
Tx: tube thoracostomy + Abx

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9
Q

influenza

  • orthomyxovirus
  • spread through respiratory droplets
  • fall/winter
  • fever, chills, malaise, HA, URI (sore throat, swollen lymph nodes, runny nose), dry cough
A

Dx: PCR
Tx: supportive/oseltamivir

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10
Q

Covid-19

  • spread through respiratory droplets
  • dysregulates renin-angiotensin-aldosterone system
  • most asymptomatic
  • loss of smell/taste
A

Dx: nasopharyngeal swab SARS Cov 2 NAAT
Tx: supportive, paxlovid if severe

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11
Q

pertussis

  • B. Pertussis
  • transmitted via respiratory droplets
  • rapid consecutive coughs followed by high pitched inspiration (whoop)
A

Dx: nasopharyngeal culture
Tx: azithromycin

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12
Q

RSV

  • Jan/Feb
  • most significant LRI cause young kids
  • major risk factor: prematurity
  • associated with airway reactivity later in life (asthma)
  • bronchiolitis
  • grunting in infant
  • crackles/ prolonged inspiration
A

Dx:
clinical based on history: bronchiolitis, URI prodrome, tachypnea, chest retractions, wheeze, crackles
Tx: Time/supportive

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13
Q

tuberculosis

  • M. tuberculosis (slow growing bacteria)
  • airborne droplets
  • common in malnourished, overcrowded populations
  • malaise, fever, wight loss, productive cough with hemoptysis, crackles heard only after short cough
A

Dx: skin test or interferon gamma assay

Tx:
DOT therapy

6 month regimen: RIPE x2 months, then only I and R x4 months

9 month regimen: RIE x4-8 weeks, then only I and R for remaining 9 months

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14
Q

aspergillosis

  • fungi: aspergillus fumigatus
  • disease of immunocompromised or critically ill
  • lungs, sinuses, brain –> MC affected
  • allergic, chronic, invasive
A

Dx:
chest CT: nodules, wedge shaped infarcts, halo sign
definitive: tissue/culture
Tx: IV voriconazole

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15
Q

CAP (outpatient)

  • outside hospital or within 48 hours after admission to hospital
  • defect in: cough reflex, mucociliary clearance system, immune response
  • fever, hypothermia, cough, inspiratory crackles, dullness to percussion
  • hospital admission based on CRB-65
  • ICU admission based on Major/minor criteria
A

Dx: CXR
Tx: azithro, doxy

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16
Q

CAP (outpatient high risk)

A

Dx: CXR
Tx: azithro, clarithro + amox, amox-clav OR resp. fluroquinolone

17
Q

CAP (inpatient not ICU)

A

Dx:CXR (CBC, CMP, ABG if hypoxic)
Tx: azithro + ceftriaxone
OR resp. fluroquinolone

18
Q

CAP (inpatient ICU)

A

Dx: CXR (CBC, CMP, ABG if hypoxic)
Tx: ceftriaxone + either azithro or resp. fluroquinolone

19
Q

CAP (PCN allergy)

A

Dx: CXR
Tx: fluoroquinolone + aztreonam

20
Q

mycoplasma pneumoniae

  • MC atypical pneumonia
  • walking pneumonia
  • summer/late fall
  • mollicute genus bacteria
  • transmitted through resp droplets
A

Dx: CXR and serology
Tx: supportive (may resolve spontaneously)
can give azithro, clarithro, doxy

21
Q

legionella pneumoniae

  • atypical PNA
  • outbreaks from contaminated water: air conditioner, portable water, cooling towers, showerheads, faucets, vents, hot tub
  • usu large facilities like hotels, hospitals, apartments
  • N/V/D
A

Dx: culture/sputum PCR
Tx: azithro, clarithro, resp. fluoroquinolone

22
Q

nosocomial pneumonia

  • HAP and VAP occur > 48 hrs after admission to hospital or following endotracheal tube intubation
  • gram pos cocci: S. aureus
  • gram neg bacilli: pseudomonas, klebsiella
  • anaerobic orgs
  • gastric acid may protect against pneumonia
A

Dx: 2 nonspecific symptoms (fever, leukocytosis, purulent sputum, worsening resp status) AND new/progressive opacity on CXR
Tx: empiric based on risk factors

23
Q

anaerobic PNA and lung abscess

  • aspiration PNA due to inhaling oropharyngeal and gastric microbes
  • people with altered consciousness
  • periodontal disease and poor dental hygiene
  • cough with foul smelling purulent sputum
A

Dx: culture with transthoracic aspiration/thoracentesis/ bronchoscopy
Tx: piperacillin-tazobactam, amox-clav, ampicillin-sulbactam OR carbapenem

24
Q

PNA in kids

  • RSV: MC infants
  • mycoplasma pneumoniae: MC > 5 years
  • GERD
  • neuro impairment
  • immunocomp
A

Dx: ??
Tx: amox (bacterial)

25
Q

asthma

  • reversible, intermittent obstructive disease
  • MC children
  • Atopy
  • WORSE @ night
  • nasal mucosal swelling, polyps, secretions

TX based on: (symptoms less than 3-5 days a week, with normal (or mildly reduced) lung function

A

Dx:
PFT: spirometry
increase >12% after bronchodilator indicates reversibility –> asthma

Tx: As need only low dose ICS-formoterol

26
Q

asthma

TX based on: symptoms most days, or waking at night once a week or more, or low lung function

A

Tx: low dose ICS-formoterol maintenance (daily) and reliever (as- needed ICS formoterol)

27
Q

asthma

TX based on: daily symptoms, walking at night once a week or more and low lung function, or recent exacerbation

A

Tx: medium dose ICS-formoterol maintenance (daily) and reliever (as- needed ICS formoterol)

28
Q
A