Dupuytren's Contracture

Question 1

What is Dupuytren’s contracture?

Answer 1

Connective tissue disorder where the palmar fascia undergoes hyperplasia. Normal fascial bands form nodules and cords progressing to contractures are the MCP and PIP joints.

Question 2

Pathology of Dupuytren’s contracture

Answer 2

Proliferation of myofibroblast cells and the production of abnormal collagen (type 3 rather than type 1)

Question 3

Risk factors of Dupuytren’s contracture

Answer 3

Male
Autosomal dominant
Northern Europe/ Scandinavian descent
Alcoholic cirrhosis
Diabetes
Peyronie's disease
Ledderhose disease

Question 4

Treatment of Dupuytren’s contracture

Answer 4

Any contracture at the PIP joint indicates surgery

More than 30 degrees of contracture at the MCP joint indicates surgery