Drugs Used To Treat Inflammation

Question 1

Type of NSAID A—–

4 functions
3 Se

Answer 1

Aspirin
Blood thinner, anti inflammation, antipyretic, analgesia

GI disturbances , allergy, ab pain

Question 2

NSAIDs type I——–
3 functions
2 Se

Answer 2

Ibuprofen
Triad
Se equals gi and nausea

Question 3

Type of NSAIDs n———–
One function
3 Se

Answer 3

Neurofen gel 5% of ibuprofen
Topical

Soft tissue injuries

Avoid eye, open wound, pregnancy

Question 4

Glucocorticoid steroids

Use: 3

Answer 4

Used for anti inflammatory, asthma immune disorders.

Question 5

Glucocorticoid steroids action
How it works
Action: 4 steps

Answer 5

How: cortisol from adrenal gland, Gluck same function regulates inflammation

Action: enters cell
Combines with steroid receptor
Activates receptor
Repressed cox 2

Question 6

Action/side effect of glucocorticoid steroids

Answer 6

Carbohydrate metabolism: conserve glucose

Fat deposition: fat shoulders face ab

Protein metabolism: muscle wasting op delayed wound healing system

Question 7

Glucocorticoid steroids 6 actions leading to delayed wound and immunosuppressive

Answer 7

Delayed wound: inhibits vasodilation
Decreases vascular permbility
Inhibits prostaglandins

Immune: reduced histamine, reduced igG production, reduced cox-2

Question 8

Type of glucocorticoid steroid
Administration
Use
Side effects

Answer 8

Prednisone
Oral
Rapid relief of symptoms triad

Side effects; skin conditions, immune disorders, osteoporosis

Question 9

NSAIDs mechanism 4

Answer 9

Inhibit cox1 and cox2 so inhibit prostaglandin (1= gastric mucosa 2=mediate pain inflam)

Inhibits vasodilation
Decreases vascular permeability

Decrease wound healing