DRUGS USED IN ASTHMA Flashcards

1
Q

True or false. Asthma is a chronic inflammatory condition ?

A

True.

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2
Q

The recurrent episodes of asthma attacks (breathlessness, coughing,wheezing and chest tightness ) usually occur during what time of the day ?

A

Night/morning

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3
Q

What is Atopy ?

A

The phenomenon of allergen sensitization.

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4
Q

The following can be triggers of Asthma except,

A. Perfume
B. Exercise
C. Stress
D. Cold air
E. Infections
F. Injury
A

Ans : F

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5
Q

IL-4 produced by the Th2 cells in the pathogenesis of Asthma work to…….

A

Stimulate IgE production

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6
Q

Repeated bouts of inflammatory in the airway of asthmatic persons undergoes structural changes termed….

A

Airway remodeling

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7
Q

The following are structural changes in airway remodeling in asthma, except

A. Hyperplasia of airway epithelium
B. Smooth muscle hypertrophy
C. Mucus gland hypertrophy

A

Ans : A

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8
Q

The most common type of asthma is ?

A

Atopic asthma

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9
Q

The most common drug triggering asthma ?

A

Aspirin

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10
Q

Name the 4 major drug classes of Anti-Asthmatic drugs .

A
  1. Bronchodilators
  2. Leukotrine Antagonists
  3. Mast cell stabilizers
  4. Corticosteroids
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11
Q

The sympathomimetic drugs have two important effects in asthma . What effects are these ?

A
  1. They help relax bronchial smooth muscle ( bronchodilators)
  2. Inhibit the release of constrictive mediators from the mast cells
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12
Q

Name atleast 4 Sympathomimetic drugs used in treating Asthma.

A
  1. Albuterol (Salbutamol)
  2. Bambuterol
  3. Epinephrine
  4. Ephedrine
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13
Q

Repeated bouts of inflammatory in the airway of asthmatic persons undergoes structural changes termed….

A

Airway remodeling

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14
Q

The following are structural changes in airway remodeling in asthma, except

A. Hyperplasia of airway epithelium
B. Smooth muscle hypertrophy
C. Mucus gland hypertrophy

A

Ans : A

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15
Q

The most common type of asthma is ?

A

Atopic asthma

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16
Q

The most common drug triggering asthma ?

A

Aspirin

17
Q

Name the 4 major drug classes of Anti-Asthmatic drugs .

A
  1. Bronchodilators
  2. Leukotrine Antagonists
  3. Mast cell stabilizers
  4. Corticosteroids
18
Q

The sympathomimetic drugs have two important effects in asthma . What effects are these ?

A
  1. They help relax bronchial smooth muscle ( bronchodilators)
  2. Inhibit the release of constrictive mediators from the mast cells
19
Q

Name atleast 4 Sympathomimetic drugs used in treating Asthma.

A
  1. Albuterol (Salbutamol)
  2. Bambuterol
  3. Salmeterol
  4. Terbutaline
20
Q

True or false, The β2 sympathomimetics have a longer duration of action than epinephrine.

A

True.