CHAPTER 53 A- ANTIMALARIAL DRUGS

Question 1

How are Malarial Drugs classified ?

Answer 1

They are classified into:

1. Tissue Schizonticides : work on the Exoerythrocytic / primary liver stages of the parasite life cycle.
2. Blood Schizonticides : Work on Erythrocytic stage of the life cycle
3. Gamtocides : act on the Gametocytes
4. Prophylactic drugs.

Question 2

Artemisinin based combination therapy (ACTs) are now popular in regard to use versus monotherapy. Why is this ?

Answer 2

This is because of increased resistance to Chloroquine and other early drug combinations.

Question 3

In Counselling patients on the prevention of malaria, it is imperative to educate them on malaria preventive measures such as Nets, Repellents, and insecticides.

Answer 3

TRUE.

Question 4

Primaquine is Unique. It has reliable efficacy against primary and latent liver stages as well as Gametocytes. It however has no place in the treatment of malaria (symptomatic). It is used to eradicating Hypnozoites causes relapses.

Answer 4

TRUE.