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Pharm 3 > Drugs to know from ppt. > Flashcards

Drugs to know from ppt. Flashcards

1
Q

Alprazolam (Xanax®)

A

Tx of anxiety and panic attacks

Benzo

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2
Q

Chlordiazepoxide (Librium®)

A

tx of anxiety, alcohol withdrawal, preoperative anxiolytic. -Benzo

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3
Q

Diazepam (Valium®) prototype Benzo

A

tx of anxiety, alcohol withdrawal, muscle relaxant, antiepileptic, antitetanus, preoperative anxiolytic
Benzo

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4
Q

Lorazepam (Ativan®)-

A

anxiety, preanesthesia anxiolytic.-Benzo

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5
Q

Temazepam (Restoril®)-

A

Hypnotic, tx of insomnia.-Benzo

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6
Q

Triazolam (Halcion®)

A

Hypnotic, tx of insomnia.-Benzo

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7
Q

Phenobarbital-Prototype Barbiturate

A

sedative-hypnotic; control of seizures; preanesthetic

Barb

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8
Q

Amobarbital

A

sedative-hypnotic; convulsions; manic reactions

Barb

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9
Q

Pentobarbital

A

sedative-hypnotic; preanesthetic

killed Marilyn Monroe

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10
Q

Secobarbital

A

Preanesthetic sedation; convulsive seizures of tetanus

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11
Q

What happens with GABA? Benzo vs. Barbit

A

GABA is an inhibitory NT. Blocks over-firing of nerve cells in CNS. Both s Increase the Duration of the GABA channel openings.

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12
Q

Imipramine (Tofranil®)- Prototype TCA

A

TCA -Relief of symptoms of depression; enuresis in children older than 6 years, off-label consideration— control of chronic pain.

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13
Q

Amitryptiline (Elavil®)

A

TCA, for depression, Anxiety, Insomnia, Tx. Resistant Depression. Chronic pain: Fibromyalgia, NP Pain, HA, Chronic Back pain. From skyscape.

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14
Q

Nortriptyline (Pamelor®)

A

TCA for Various Depression. Off Label for Chronic Neurogenic Pain.. skyscape.

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15
Q

Isocarboxazid (Marplan)

A

MAOI-Used for patients who do not respond to or cannot take newer, safer antidepressants

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16
Q

Phenelzine (Nardil) Prototype MAOI

A

Used for some patients who do not respond to newer, safer antidepressants

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17
Q

Tranylcypromine (Parnate)

A

MAOI- Used for adult outpatients with reactive depression

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18
Q

Fluoxetine (Prozac®)-Prototype SSRI

A

Tx of depression, bulimia, OCDs, panic disorders, PMDD in adults; also under investigation for Tx of other psychiatric disorders, including obesity, alcoholism, chronic pain, and various neuropathies

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19
Q

Paroxetine (Paxil®)

A

SSRI-Tx of depression, OCDs, PMDD, PTSD reaction, social anxiety disorders, GAD, and various panic disorders in adults; also under investigation for treatment of chronic headache, diabetic neuropathy, and hot flashes

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20
Q

Sertraline (Zoloft®)

A

SSRI-Tx of depression, OCDs, social anxiety disorder, post- traumatic stress disorder, panic disorders, PMDD

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21
Q

Citalopram (Celexa®)

A

SSRI-Tx of depression in adults has also been used to treat panic disorder, premenstrual dysphoric disorder (PMDD), obsessive–compulsive disorders (OCDs), social phobias, trichotillomania, PTSD

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22
Q

Duloxetine (Cymbalta®)

A 
SSRI-Major Depressive Disorder
Diabetic Neuropoathic pain
GAD
Fibromyalgia
Chronic musculoskeletal pain and Stress Urinary incontinence (skyscape)
23
Q

Escitalopram (Lexapro®)

A

SSRI-Tx major depressive disorder, maintenance of patients with major depressive disorder and generalized anxiety disorder

24
Q

Bupropion (Wellbutrin, Zyban)

A

Weakly blocks reuptake of NE, dopamine, 5HT. Treats depression and at lower doses can be used as a smoking cessation agent.

25
Trazodone (Desyrel)
Mainly blocks 5HT. Many CNS side effects and dose needs to be high for antidepressant use. Mainly used for sleep aid. Can cause priapism (prolonged erection lasting >4hrs)
26
Venlafaxine (Effexor)
Mildly blocks reuptake of NE, 5HT and dopamine. Used for GAD, SAD, decreases addictive behavior. Has fewer CNS side effects than trazodone-available in sustained release.
27
Chlorpromazine (Thorazine®)
Typical Antipsychotic-Decrease pre-op restlessness, intermittent porphyria, control N/V, intractable hiccups
28
Haloperidol (Haldol®)
Typical Antipsychotic-treats acute psych situations and available IV for use when swallowing difficulties are present
29
Prochlorperazine (Compazine®)
Typical Antipsychotic-used to control N/V associated with chemo and surgery. Available oral, parenteral and rectal
30
Methylphenidate (Ritalin ®, Concerta ®)
CNS Stimulant Tx of ADD and Narcolepsy
31
Atomoxetine (Strattera ®)
CNS Stimulant-Tx of ADD | Modafinil (Provigil ®)-Tx of Narcolepsy
32
Modafinil (Provigil ®)
CNS Stimulant-Tx of Narcolepsy
33
Clozapine (Clozaril®)-
Atypical Antipsychotic-Tx schizophrenia **Important to monitor WBC count and compliance-only give 1wk supply at a time**
34
Olanzapine (Zyprexa®)
Atypical Antipsychotic-Txs bipolar and agitation
35
Quetiapine (Seroquel®)
Atypical Antipsychotic-short term Tx of acute manic episodes a/w bipolar
36
Risperidone (Risperdal®)
Atypical Antipsychotic-Tx irritability and aggression a/w autistic d/o in children and adolescents, as well as for acute manic episodes of bipolar
37
Drugs Used to Treat Mania/ Bipolar Disease
Lithium salts (Lithane, Lithotabs) Lamotrigine (Lamictal) Olanzapine (Zyprexa) Quetiapine (Seroquel)
38
Normal Lithium serum levels
*Normal therapeutic serum level is 0.6-1.2mEq/L
39
Effects for Lithium serum levels > 1.2 but less than 1.5:
Effects directly related to the lithium serum level: lethargy, slurred speech, muscle weakness, nausea, and vomiting
40
Levels 1.5 to 2:
Effects directly related to the lithium serum level: Intensification of rxn. Plus ECG changes. rxn = lethargy, slurred speech, muscle weakness, nausea, and vomiting
41
Levels 2 to 2.5:
Effects directly related to the lithium serum level: ataxia, clonic movements, hyper-reflexia, and seizures
42
Levels greater than 2.5:
Effects directly related to the lithium serum level: complex multi-organ toxicity and significant risk of death
43
Buprenorphine (Buprenex)
Treats mild to moderate pain | Narcotic Agonists–Antagonists
44
Butorphanol (Stadol, Stadol NS)
Preoperative medication Relieves moderate to severe pain Narcotic Agonists–Antagonists
45
Nalbuphine (Nubain)
Treats moderate to severe pain Adjunct for general anesthesia Relieves pain during labor and delivery Narcotic Agonists–Antagonists
46
Pentazocine (Talwin) **prototype med**
Relief of moderate to severe pain during labor and delivery; treatment of postpartum pain; used as an adjunct to general anesthesia Preferred drug for patients switched from parenteral to oral forms after surgery or labor Narcotic Agonists–Antagonists
47
Naloxone (Narcan)
Reverses adverse effects of narcotics; diagnoses suspected acute narcotic overdose Narcotic Antagonist
48
Nalmefene (Revex)
Reverses the effects of narcotics; manages known or suspected narcotic overdose Narcotic Antagonist
49
Naltrexone (ReVia)
Used orally in the management of alcohol or narcotic dependence Narcotic Antagonist
50
Fluoxetine Prototype SSRI
Treatment of depression, obsessive– compulsive disorders, bulimia, premenstrual dysphoric disorder, panic disorders; off-label uses include chronic pain, alcoholism, neuropathies, obesity. *Widely used to tx depression in adolescents. Off label usage for kids as young as 6 months.
51
Phenelzine Prototype MAOI
Tx depression pt. who are unresponsive or other antidepressive therapy is contraindicated. *Food interactions-potentially fatal HTN crisis. Tyramine containing foods.
52
Imipramine Prototype TCA
Tx depression; enuresis in children 6+ years, off-label consideration— control of chronic pain.
53
Phenobarbital Prototype Barbiturate
Sedation, short-term Tx insomnia, long-term Tx tonic–clonic seizures and cortical focal seizures, emergency control of certain acute convulsive episodes, preanesthetic
54
Diazepam Prototype Benzo
Mgmt. of anxiety disorders, acute alcohol withdrawal, muscle relaxation, treatment of tetanus, antiepileptic adjunct in status epilepticus, Pre-Op relief of anxiety and tension.

Pharm 3 (7 decks)

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