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Pharm 3 > Drugs to know from ppt. > Flashcards

Drugs to know from ppt. Flashcards

1
Q

Alprazolam (Xanax®)

A

Tx of anxiety and panic attacks

Benzo

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2
Q

Chlordiazepoxide (Librium®)

A

tx of anxiety, alcohol withdrawal, preoperative anxiolytic. -Benzo

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3
Q

Diazepam (Valium®) prototype Benzo

A

tx of anxiety, alcohol withdrawal, muscle relaxant, antiepileptic, antitetanus, preoperative anxiolytic
Benzo

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4
Q

Lorazepam (Ativan®)-

A

anxiety, preanesthesia anxiolytic.-Benzo

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5
Q

Temazepam (Restoril®)-

A

Hypnotic, tx of insomnia.-Benzo

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6
Q

Triazolam (Halcion®)

A

Hypnotic, tx of insomnia.-Benzo

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7
Q

Phenobarbital-Prototype Barbiturate

A

sedative-hypnotic; control of seizures; preanesthetic

Barb

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8
Q

Amobarbital

A

sedative-hypnotic; convulsions; manic reactions

Barb

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9
Q

Pentobarbital

A

sedative-hypnotic; preanesthetic

killed Marilyn Monroe

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10
Q

Secobarbital

A

Preanesthetic sedation; convulsive seizures of tetanus

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11
Q

What happens with GABA? Benzo vs. Barbit

A

GABA is an inhibitory NT. Blocks over-firing of nerve cells in CNS. Both s Increase the Duration of the GABA channel openings.

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12
Q

Imipramine (Tofranil®)- Prototype TCA

A

TCA -Relief of symptoms of depression; enuresis in children older than 6 years, off-label consideration— control of chronic pain.

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13
Q

Amitryptiline (Elavil®)

A

TCA, for depression, Anxiety, Insomnia, Tx. Resistant Depression. Chronic pain: Fibromyalgia, NP Pain, HA, Chronic Back pain. From skyscape.

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14
Q

Nortriptyline (Pamelor®)

A

TCA for Various Depression. Off Label for Chronic Neurogenic Pain.. skyscape.

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15
Q

Isocarboxazid (Marplan)

A

MAOI-Used for patients who do not respond to or cannot take newer, safer antidepressants

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16
Q

Phenelzine (Nardil) Prototype MAOI

A

Used for some patients who do not respond to newer, safer antidepressants

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17
Q

Tranylcypromine (Parnate)

A

MAOI- Used for adult outpatients with reactive depression

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18
Q

Fluoxetine (Prozac®)-Prototype SSRI

A

Tx of depression, bulimia, OCDs, panic disorders, PMDD in adults; also under investigation for Tx of other psychiatric disorders, including obesity, alcoholism, chronic pain, and various neuropathies

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19
Q

Paroxetine (Paxil®)

A

SSRI-Tx of depression, OCDs, PMDD, PTSD reaction, social anxiety disorders, GAD, and various panic disorders in adults; also under investigation for treatment of chronic headache, diabetic neuropathy, and hot flashes

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20
Q

Sertraline (Zoloft®)

A

SSRI-Tx of depression, OCDs, social anxiety disorder, post- traumatic stress disorder, panic disorders, PMDD

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21
Q

Citalopram (Celexa®)

A

SSRI-Tx of depression in adults has also been used to treat panic disorder, premenstrual dysphoric disorder (PMDD), obsessive–compulsive disorders (OCDs), social phobias, trichotillomania, PTSD

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22
Q

Duloxetine (Cymbalta®)

A 
SSRI-Major Depressive Disorder
Diabetic Neuropoathic pain
GAD
Fibromyalgia
Chronic musculoskeletal pain and Stress Urinary incontinence (skyscape)
23
Q

Escitalopram (Lexapro®)

A

SSRI-Tx major depressive disorder, maintenance of patients with major depressive disorder and generalized anxiety disorder

24
Q

Bupropion (Wellbutrin, Zyban)

A

Weakly blocks reuptake of NE, dopamine, 5HT. Treats depression and at lower doses can be used as a smoking cessation agent.

25
Q

Trazodone (Desyrel)

A

Mainly blocks 5HT. Many CNS side effects and dose needs to be high for antidepressant use. Mainly used for sleep aid. Can cause priapism (prolonged erection lasting >4hrs)

26
Q

Venlafaxine (Effexor)

A

Mildly blocks reuptake of NE, 5HT and dopamine. Used for GAD, SAD, decreases addictive behavior. Has fewer CNS side effects than trazodone-available in sustained release.

27
Q

Chlorpromazine (Thorazine®)

A

Typical Antipsychotic-Decrease pre-op restlessness, intermittent porphyria, control N/V, intractable hiccups

28
Q

Haloperidol (Haldol®)

A

Typical Antipsychotic-treats acute psych situations and available IV for use when swallowing difficulties are present

29
Q

Prochlorperazine (Compazine®)

A

Typical Antipsychotic-used to control N/V associated with chemo and surgery. Available oral, parenteral and rectal

30
Q

Methylphenidate (Ritalin ®, Concerta ®)

A

CNS Stimulant Tx of ADD and Narcolepsy

31
Q

Atomoxetine (Strattera ®)

A

CNS Stimulant-Tx of ADD

Modafinil (Provigil ®)-Tx of Narcolepsy

32
Q

Modafinil (Provigil ®)

A

CNS Stimulant-Tx of Narcolepsy

33
Q

Clozapine (Clozaril®)-

A

Atypical Antipsychotic-Tx schizophrenia Important to monitor WBC count and compliance-only give 1wk supply at a time

34
Q

Olanzapine (Zyprexa®)

A

Atypical Antipsychotic-Txs bipolar and agitation

35
Q

Quetiapine (Seroquel®)

A

Atypical Antipsychotic-short term Tx of acute manic episodes a/w bipolar

36
Q

Risperidone (Risperdal®)

A

Atypical Antipsychotic-Tx irritability and aggression a/w autistic d/o in children and adolescents, as well as for acute manic episodes of bipolar

37
Q

Drugs Used to Treat Mania/Bipolar Disease

A

Lithium salts (Lithane, Lithotabs)
Lamotrigine (Lamictal)
Olanzapine (Zyprexa)
Quetiapine (Seroquel)

38
Q

Normal Lithium serum levels

A

*Normal therapeutic serum level is 0.6-1.2mEq/L

39
Q

Effects for Lithium serum levels > 1.2 but less than 1.5:

A

Effects directly related to the lithium serum level: lethargy, slurred speech, muscle weakness, nausea, and vomiting

40
Q

Levels 1.5 to 2:

A

Effects directly related to the lithium serum level: Intensification of rxn. Plus ECG changes. rxn = lethargy, slurred speech, muscle weakness, nausea, and vomiting

41
Q

Levels 2 to 2.5:

A

Effects directly related to the lithium serum level: ataxia, clonic movements, hyper-reflexia, and seizures

42
Q

Levels greater than 2.5:

A

Effects directly related to the lithium serum level: complex multi-organ toxicity and significant risk of death

43
Q

Buprenorphine (Buprenex)

A

Treats mild to moderate pain

Narcotic Agonists–Antagonists

44
Q

Butorphanol (Stadol, Stadol NS)

A

Preoperative medication
Relieves moderate to severe pain
Narcotic Agonists–Antagonists

45
Q

Nalbuphine (Nubain)

A

Treats moderate to severe pain
Adjunct for general anesthesia
Relieves pain during labor and delivery
Narcotic Agonists–Antagonists

46
Q

Pentazocine (Talwin) prototype med

A

Relief of moderate to severe pain during labor and delivery; treatment of postpartum pain; used as an adjunct to general anesthesia
Preferred drug for patients switched from parenteral to oral forms after surgery or labor
Narcotic Agonists–Antagonists

47
Q

Naloxone (Narcan)

A

Reverses adverse effects of narcotics; diagnoses suspected acute narcotic overdose
Narcotic Antagonist

48
Q

Nalmefene (Revex)

A

Reverses the effects of narcotics; manages known or suspected narcotic overdose
Narcotic Antagonist

49
Q

Naltrexone (ReVia)

A

Used orally in the management of alcohol or narcotic dependence
Narcotic Antagonist

50
Q

Fluoxetine Prototype SSRI

A

Treatment of depression, obsessive– compulsive disorders, bulimia, premenstrual dysphoric disorder, panic disorders; off-label uses include chronic pain, alcoholism, neuropathies, obesity.
*Widely used to tx depression in adolescents. Off label usage for kids as young as 6 months.

51
Q

Phenelzine Prototype MAOI

A

Tx depression pt. who are unresponsive or other antidepressive therapy is contraindicated. *Food interactions-potentially fatal HTN crisis. Tyramine containing foods.

52
Q

Imipramine Prototype TCA

A

Tx depression; enuresis in children 6+ years, off-label consideration— control of chronic pain.

53
Q

Phenobarbital Prototype Barbiturate

A

Sedation, short-term Tx insomnia, long-term Tx tonic–clonic seizures and cortical focal seizures, emergency control of certain acute convulsive episodes, preanesthetic

54
Q

Diazepam Prototype Benzo

A

Mgmt. of anxiety disorders, acute alcohol withdrawal, muscle relaxation, treatment of tetanus, antiepileptic adjunct in status epilepticus, Pre-Op relief of anxiety and tension.

Pharm 3 (7 decks)

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