Drugs to Avoid in Pregnancy

Question 1

Nitrous Oxide

Answer 1

↑ adrenergic tone which leads to vasoconstriction of uterine vessels and ↓ uterine blood flow.

Question 2

Benzodiazepines

Answer 2

Some concerns that it may cause cleft palate. OK in third trimester

Question 3

Toradol

Answer 3

Premature closure of ductus arteriosus.

Question 4

NMDA Antagonists (Ketamine)

Answer 4

GABA enhancers may cause apoptotic neurodegeneration that leads to persistent memory loss in rats.