Drugs that weaken the bacterial cell wall Flashcards

1
Q

Which drug is safest on the kidneys?

A

penicillin

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2
Q

common allergic reaction for penicillin

A

rash

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3
Q

adverse effect for penicillin

A

anaphylaxis

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4
Q

if a patient is allergic to pencillin, what med should they NOT take? (contraindicated)
What is the alternative

A

cephalosporin

micins: i.e. gentamicin (aminoglycoside)

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5
Q

what bacteria is resistant to penicillin

A

Staph

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6
Q

type of bacterial infection pencillin is most effective in treating

A

gram neg.

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7
Q

type of pencillin that can only be administered IV

A

G

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8
Q

pencillin should not be COMBINED with what types of drugs?

A

aminoglycosides (gentamicin)

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9
Q

What is the trade name for cephalexin?

A

keflex

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10
Q

what is the ROA for cephalosporin

A

parental (nonoral)

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11
Q

when is cephalsporins most effective?

A

when bacteria is growing and dividing

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12
Q

which generation of cephalosporin is non resistant to beta lactamases (cephalosporinases)

A

1st

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13
Q

what are signs of superinfections to report with cephalosporin?

signs of CDAD (c diff)

A

vaginal itching, loose stool, furry tongue

C diff: diarrhea and blood in mucus

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14
Q

major adverse effects with cephalosporin?

A

steven-johnsons
anaphylaxis
rash

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15
Q

Why would alcohol be dangerous to ingest when taking cephalosporin?

A

causes internal bleeding- dangerous with warfarin (anticoagulant)

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16
Q

What is the #1 choice for treating MRSA?

A

vancomycin

17
Q

What is the major side effect when taking vancomycin?

how to prevent?

A

red man syndrome (red skin)
rash

IV infuse over at least 60 min

18
Q

How to check for signs of renal toxicity?

A

check creatinine and trough levels (before administering next dose) to make sure not administering too much