Drugs that inhibit bacterial protein synthesis Flashcards

1
Q

tetracycline- cidal or static

A

static

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2
Q

when to take tetracycline

A

on empty stomach

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3
Q

major side effect with tetracycline

A

stains teeth/damage enamel
Steven Johnson
CDAD

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4
Q

who should not take tetracycline

A

preg/breastfeed/child <8 yo

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5
Q

superinfections caused from tetracycline

A

C diff (diarrhea–> dehydration, hypokalemia–> dysrhythmia), candida( yeast infection)

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6
Q

Tetracycline is used to treat what as well?

A

acne

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7
Q

what decreases absorption of tetracycline

A

milke, Mg2+, Fe, Ca 2+, antacids

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8
Q

Tetracycline should not be used with what or else will cause fatal kidney toxicity

A

methoxyflurane

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9
Q

erythromycin is what type of drug

A

macrolide

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10
Q

erythromycin can be used if patient is allergic to what?

A

penicillin

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11
Q

erythromycin used to treat what?

A

whooping cough

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12
Q

adverse effects of eryhomycin?

A

GI, QT prolongation, superinfections, thrombophlebitis (via IV), ototox.

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13
Q

Clindamycin can treat what type of bacteria

A

anaerobic

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14
Q

major side effect of clindamycin

A

can promote CDAD (c diff infection)

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15
Q

What is used as an alternative to penicillin allergy?

A

erythromycin
clindamycin
gentmycin

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16
Q

neosporin is what type of drug

A

gentamycin

17
Q

major adverse effect of gentamycin

A

ototox- hearing loss, tinnitus

18
Q

since gentamycin is toxic to the kidneys, what should we monitor?

A

trough**/peak

19
Q

gentamycin is what type of drug

A

aminoglycoside

20
Q

which drug can be used to treat UTI

A

Bactrim

21
Q

major adverse effects for Bactrim

A

steven johnson-skin blister, can’t regulate body temp, kidney damage
hyperkalamia
birth dfect

22
Q

which drug should not take if have a sulfa allergy

A

bactrim