Drugs that inhibit bacterial protein synthesis Flashcards
tetracycline- cidal or static
static
when to take tetracycline
on empty stomach
major side effect with tetracycline
stains teeth/damage enamel
Steven Johnson
CDAD
who should not take tetracycline
preg/breastfeed/child <8 yo
superinfections caused from tetracycline
C diff (diarrhea–> dehydration, hypokalemia–> dysrhythmia), candida( yeast infection)
Tetracycline is used to treat what as well?
acne
what decreases absorption of tetracycline
milke, Mg2+, Fe, Ca 2+, antacids
Tetracycline should not be used with what or else will cause fatal kidney toxicity
methoxyflurane
erythromycin is what type of drug
macrolide
erythromycin can be used if patient is allergic to what?
penicillin
erythromycin used to treat what?
whooping cough
adverse effects of eryhomycin?
GI, QT prolongation, superinfections, thrombophlebitis (via IV), ototox.
Clindamycin can treat what type of bacteria
anaerobic
major side effect of clindamycin
can promote CDAD (c diff infection)
What is used as an alternative to penicillin allergy?
erythromycin
clindamycin
gentmycin
neosporin is what type of drug
gentamycin
major adverse effect of gentamycin
ototox- hearing loss, tinnitus
since gentamycin is toxic to the kidneys, what should we monitor?
trough**/peak
gentamycin is what type of drug
aminoglycoside
which drug can be used to treat UTI
Bactrim
major adverse effects for Bactrim
steven johnson-skin blister, can’t regulate body temp, kidney damage
hyperkalamia
birth dfect
which drug should not take if have a sulfa allergy
bactrim
