Drugs that cause enzyme induction Flashcards
1
Q
Carbamazepine
A
CYP1A2/CYP2B6/CYP2C9/CYP2C19/CYP3A
2
Q
Nicotine
A
CYP1A2
3
Q
Phenobarbital
A
CYP3A
4
Q
Phenytoin
A
CYP1A2/CYP3A
5
Q
Rifabutin
A
CYP3A
6
Q
Rifampin
A
CYP1A2/CYP2C8/CYP2C9/CYP3A
7
Q
Troglitazone
A
not complete
8
Q
Modafanil
A
CYP3A
9
Q
St John’s Wort
A
CYP3A
10
Q
Alcohol
A
not complete
11
Q
Sulfonylureas
A
not complete
12
Q
Griseofulvin
A
not complete
13
Q
Primidone
A
not complete
14
Q
Protease Inhibitors (Nelfinavir/Ritonavir/Indinavir/Saquinavir)
A
CYP3A
15
Q
What is the enzyme inducer pneumonic?
Full and current list of enzyme inducers available at: https://drug-interactions.medicine.iu.edu/Main-Table.aspx
A
S - sulfonylureas C - carbamazepine R - rifampin/rifabutin A - alcohol P - phenytoin . G - griseofulvin P - phenobarbitone/primidone
& protease inhibitors (e.g. ritonavir)
