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Kaplan: Endocrine Pharmacology > Drugs Related to Hypothalamic and Pituitary Hormones > Flashcards

Drugs Related to Hypothalamic and Pituitary Hormones Flashcards

1
Q

Somatrem of somatropin MOA?

A

GH analog

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2
Q

Octreotide MOA?

A

somatostatin analog

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3
Q

Cosyntropin MOA?

A

ACTH analog

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4
Q

Urofollitropin MOA?

A

FSH analog

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5
Q

Placental HCG MOA?

A

LH analog

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6
Q

Menotropins MOA?

A

FSH and LH analogs

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7
Q

Cabergoline MOA?

A

PIH (prolactin inhibiting hormone) (DA) analog

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8
Q

Oxytocin indications?

A

labor induction

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9
Q

Desmopressin MOA?

A

vasopressin analog

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10
Q

Indications for somatropin?

A

pituitary dwarfism, osteoporosis

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11
Q

Indications for octreotide?

A

acromegaly, carcinoid and secretory- GI tumors

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12
Q

Indictions Cosyntropin

A

Infantile spasms

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13
Q

Indications nafarelin?

A

endometriosis, prostate carcinoma (repository form)

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14
Q

Indication Cabergoline?

A

hyperprolactinemia

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15
Q

Indications Desmopressin (V2 selective)?

A
  • neurogenic (pituitary) DI
  • Hemophilia A (inc. factor VIII from liver)
  • von Willebrand disease (inc. vW factor from endothelium)
  • Primary nocturnal enuresis
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16
Q

What are the indications for leuprolide use?

A

endometriosis, prostate carcinoma (repository form)

17
Q

What is the use for placental HCG?

A

hypogonadal states

18
Q

Indications for menotropins?

A

hypogonadal states

19
Q

Indications for urofollitropin?

A

hypogonadal states

20
Q

What are some drugs used to treat SIADH?

A

demeclocyline, tolvaptan, loop diuretics

21
Q

MOA demeclocyline which makes it useful in treating SIADH?

A

V2 receptor blockers in collecting duct

Kaplan: Endocrine Pharmacology (5 decks)

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