drugs on CVS Flashcards
which agent is more likely to cause arrhythmias when given with halothane?
adrenaline
what is meant by 1:1000 adrenaline?
1mg/ml
hence in cardiac arrest give 1ml
can also come as 1:10000 = 1mg in 10ml
which are the categories of the classic vaughan- williams classification?
Na channel blockers
B blockers
K channel blockers
CaCB
how many phases of cardiac AP?
5
resting = phase 4
upstroke = phase 0
platau = phase 2
how many phases of pacemaker potential?
3
phase 4
upstroke = phase 0
downstroke = phase 3
what refractory period is at phase 2 of cardiac AP?
absolute
which class of anti-arrhythmics is classed as the membrane stabilising drugs?
class I
which class of antiarrhythmics is each of lidocaine, flecainide and quindine
lidocaine = 1b
flecanide = 1c
quinidine = 1a
which types of arrhythmias do the following typically treat…
a) digoxin
b) amiodarone
c) flecainide
d) lidocaine
e) verapamil
Verapamil and digoxin are used to treat supraventricular tachycardias.
Flecainide, like lidocaine, can be used for ventricular tachycardias but can also be used for junctional re-entry tachyarrhythmias.
amiodarone for ventricular
what is the Sicilian Gambit classification?
anti-arrhythmic classication based on molecular targets
during phase 2 of cardiac AP which channels does calcium enter through?
L type - slow
what are the 3 mechanisms of arrhythmias?
triggered activity - e.g.torsades
enhanced automaticity e.g. sinus tachy.
re-entry - e.g. WPW
which class of anti arrhythmics is sotolol?
class 2 & 3
what does flecanide do to PR?
lengthens
what drugs can contraindicated in WPW?
B blockers
CaCB
digoxin
class Ic
