Drugs of the day 2 Flashcards

1
Q

Doxycycline

A

B: Vibramycin
C: Tetracycline antibiotic
- DOC for Lyme or RMSI
- 2nd line for Community-acquired Pneumonia
- Used for Chlamydia / STD
- SE: Tooth discoloration, Not for use in <8yo
- Avoid Divalent & Trivalent cations (milk,calcium, magnesium)

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2
Q

Enalaprilat

A

B: Vasotec
C: ACE inhibitor (Only IV agent in the class)
- Used for Hypertension
-Used for Heart Failure
- SE: Cough, Hyperkalemia, angioedema
- Not used in pregnancy

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3
Q

Enoxaparin

A

B: Lovenox
C: Low molecular weight heparin
Use: Tx & Px of DVT, Pulmonary embolism
SE: Bleeding

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4
Q

Epinephrine

A

B: N/A
C: Vasopressor
U: Cardiogenic shock, Anaphylaxis
SE: Headache, Tremors, Restless

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5
Q

Epoetin Alfa

A

B: Epogen or Procrit (SA compared to Arnesep)
C: Colony stimulating factor
U: Anemia due to chemotherapy & chronic renal failure
SE: Hypertension, bone pain
BBW: Increased risk of mortality due to MI, Stroke, VTE

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6
Q

Ertapenem

A

B: Invanz
C: Carbapenem Antibiotic
U: Gram +ve & -ve infections
SE: Cross Sensitivity to Pen, Ceph
Narrow spectrum
Not cover pseudomonas
IV only
Cidal

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7
Q

Erythromycin

A

B: Erythrocin
C: Macrolide Antibiotic
U: Used for its side effects, Gastroparesis ( increase gut motility)
SE: Severe GI effects, QT prolongation
Many drug interactions
Major P450 inhibitor
Static

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8
Q

Esomeprazole

A

B: Nexium
C: PPI
U: GERD, PUD, Prevent Stress Ulcers
SE: Well tolerated
Avoid Plavix and use Pantoprazole instead

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9
Q

Famotidine

A

B: Pepcid
C: H2 histamine antagonist
U: GERD, PUD, Prevent Stress Ulcer
SE: Well tolerated

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10
Q

Fentanyl

A

B: N/A
C: Opioid agonist
U: Moderate - Severe pain, pre & post Operation
SE: Constipation, Hypotension, Bradycardia, Respiratory depression < Morphine

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11
Q

Filgrastim

A

B: Neupogen
C: Colony Stimulating Factor
U: ^ WBC production in (Neutropenia, Chemo/ Other sick patients)
SE: Bone pain, Fever, Thrombocytopenia( low platelets)

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12
Q

Fluconazole

A

B: Diflucan
C: Antifungal
U: Tx Fungal infection by Candida, & (immunocompromised patients)
SE: ^LFTs, Nausea, Vomiting
Lower dose in PT with compromised kidney
P450 Inhibitor = Drug interactions
IV / PO HAVE >90% bioavailability

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13
Q

Fosphenytoin

A

B: Cerebyx
Class: Anticonvulsant
U: status epilepticus
Conc. / Ro are expressed in PE
Levels need to be gotten
SE.Toxic: Nystagmus, ataxia, decrease mental status, Parasthesias
IV ONLY

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14
Q

Furosemide

A

B: Lasix
C:Loop diuretic
U: Edema associated with heart, hepatic, & renal Faliure
SE: Hypokalemia,Hypotension
IV / PO

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15
Q

Gentamycin

A

B: N/A
C: Aminoglycoside antibiotics
U: Tx Gram-ve infection (Pseudomonas)
SE: Ototoxixity, Nephrotox
Must draw peak and trough levels(narrow therapeutic window)
IV

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16
Q

Haloperidol

A

B:Haldol
C:Typical antipsychotic agent
U: Schizophrenia, acute psychosis, aggressive/agitated behavior
SE: Extrapyramidal reactions ( tardive dyskinesia), hypotension, tachycardia, respiratory depression, QT
prolongation
Salt forms: Lactate (IVorIM) Decanoate(IM)

17
Q

Heparin

A

B: N/A
C: Anticoagulant
U: Tx & Px of clot (DVT, PE, IM)
SE: Bleeding HIT (Heparin Induced Thrombocytopenia
Monitor: aPPT, hemoglobin, hemotocrit
Narrow therapeutic window

18
Q

Hydralazine

A

B: N/A
C: Potent Vasodialator Antihypertensive
U: Hypertension, Preeclampsia
SE: Tachycardia, Hypotension, Reflex Tachycardia

19
Q

Hydrocortisone

A

B: Solu- Cortef
C: Glucocorticosteriod
U: Severe pulmonary disease, Septic shock, Addison disease
SE: Cushing, hyperglycemia, arrhythmia, psychosis
^WBC, Blood Sugar

20
Q

Hydromorphone

A

B: Dilaudid
C: Opiate analgesic
U: Severe Pain
SE: Respiratory Depression, Bradycardia, Hypotension, Sedation
Dilaudid > Morphin

21
Q

Imipenem- Cilastatin

A

B: Primaxin
C: Carbapenem Antibiotic
U: Infection by multidrug resistant organism + Pseudomonas
SE: Seizure, Pen & Ceph Sensitivity,
Cidal

22
Q

Infliximab

A

B: Remicade
C: Monoclonal antibody
U: Rheumatoid A, Crohn, Ulcerative colitis
SE: Headache, HTN, infusion related reactions, increased risk of infection

23
Q

Ketorolac

A

B: Toradol
C: NSAID
U: POST OP Pain
SE: N/V, abdominal pain( Ulcer, PUD)
Not > 5days. Increase risk of MI, STROKE, GI, BLEEDING

23
Q

Labetalol

A

B: N/A
C:Nonselective β blocker with α blocking ability
U:HTN, HTN crisis, angina
SE: Orthostatic hypotension, bradycardia, dizziness

Not for asthmatics & COPD

23
Q

Leucovorin

A

B: N/A
C: Chemotherapy modulating agent
U: rescue agent for methotrexate SE, Megaloblastic anemia due to folate deficiency
SE: Thrombocytosis, allergic reaction

24
Q

Levofloxacin

A

B: Levaquin
C: Fluroquinolone antibiotic
U: Wide range of Gram -ve & +ve, UTI, Community acquired pneumonia
SE: Tendon rupture, impaired cartilage development, QT prolongation, (ELDERLY: HTN, CVD, Aortic aneurysm)
Avoid: <18yo(used in cystic fibrosis), pregnancy, divalent & trivalent cation

CIDAl

25
Q

Levothyroxine

A

B: Synthroid
C: Thyroid hormone
U: Hypothyrodisim
SE: Tachycardia, HTN, arrhythmia, flushing, weightloss, anxiety, feeling hot, hair loss
Takes 6 weeks for result, take on empty stomach

26
Q

Lidocaine

A

B: Xylocaine
C: Local anesthetic ( surgery), Ventricular arrhythmia (V.fib, v.tach)
SE: Drowsiness, dizziness, confusion

27
Q

Linezolid

A

B: Zyvox (non-selective MAOI)
C: Oxazolidinone antibiotic
U: Gram +ve infection, DOC for Vancomycin Resistant Enterococcus(VRE), MRSA
SE: Myelosuppression (>2wk),
DI: Serotonin syndrome when used with SSRI, TCA, Triptan, DEMOROL

28
Q

Lorazepam

A

B: Ativan
C: Benzodiaze4pine
U: Status epilepticus, antiemetic adjunct, anxiety, preanesthetic,
SE: CVD, Resp depressin, drowsiness, dizziness
DI: Opioid

29
Q

Mannitol

A

B: Osmitrol
C: Osmotic diuretic
U: decrease intracranial pressure, TX/PX acute renal faliure
SE: Heart faliure, Hyponatremia, hypokalemia
Stability: Crystal form, so warm in bath & cool B4 administering

30
Q

Meperidine

A

B: Demerol
C: Opiate agonist
U: Post-op shivering, moderate - severe pain
SE: Respiratory& Circulatory depression
Only use for <48hr due to too much normeperidine metabolite(renal faliure)
DI: Serotonin syndrome when used with SSRI, TCA, Triptan, Linezolid

31
Q

Meropenem

A

B: Merrem
C: Carbapenem antibiotic
U: Multi drug resistant infection + Pseudomonas
SE: Pen & Ceph sensitivity

32
Q

Methylprednisone

A

B: Solu-Medrol
C: Glucocorticosteroid
U: Immunosuppressant ( transplant, autoimmune), Anti-inflammatory(pulmonary disease, cerebral edema, spinal cord injury)
SE: Cushing, psychosis, hyperglycemia, osteoporosis(calcium +vitamin D supplement), ^WBC
SUCCINATE(IV)
ACETATE(IM, Depo-medrol)

33
Q

Metoclopramide

A

B: Reglan
C: Prokinetic & Antiemetic (DA receptor Blocker)
U: DM gastroparesis, GERD, CHEMO-Nausea, PX Vomiting
SE: Drowsiness, EPS, Tardive dyskinesia
DI: Anti-psychotic
Avoid in Elderly & those in Renal Inssuficency